Researchers from North Carolina State University have developed a high - throughput technique that can determine if a chemical has the potential to
activate key genes in seconds rather than the typical 24 hours or more.
A new technique can determine if a chemical has the potential to
activate key genes in seconds rather than the typical 24 hours or more.
Kriegstein notes that the hunt will likely commence for small molecules capable of
activating the key genes.
Not exact matches
Key proteins, produced and regulated by these important
genes,
activated a cascade of diverse, tissue - specific signals that led to regenerative organ growth.
This caused two
key genes normally
activated solely on the left side of the body to be expressed on the right side, the team reports in the 4 July issue of Nature.
The
gene plays a
key role in cellular proliferation and is
activated in 90 % of all human pancreatic tumors.
But the message receiver can turn on the
key genes and make the colors light up by pressing the nitrocellulose paper into an agar plate containing a chemical trigger that
activates expression of the fluorescent proteins.
Some researchers have argued that endogenised retroviruses may be
key to how species diverge from each other, by
activating different body plans and
gene networks that may give one individual an edge over other members of the species.
Nagahashi M, Takabe K, Liu R, Wang Y, Hait NC, Wang X, Allegood JC, Yamada A, Aoyagi T, Liang J, Pandak WM, Cooper P, Spiegel S, Hylemon PB, and Zhou H. Conjugated Bile Acid
Activated S1P Receptor 2 Is a
Key Regulator of Sphingosine Kinase 2 and Hepatic
Gene Expression.
In 1996, for instance, Semenza demonstrated that HIF - 1
activates the
gene for a
key participant in blood - vessel formation, vascular endothelial growth factor (VEGF).
Curcumin
activates PPAR (peroxisome proliferator - activator receptor) which is a group of
key nuclear proteins that regulate
gene expression and modulate sugar uptake and utilization in the bloodstream.
But they may also
activate the
gene atrogin - 1
gene, which plays a
key role in muscle atrophy.