Sentences with phrase «activated by an enzyme»

Ethionamide in particular is activated by the enzyme EthA, but some resistant forms of tuberculosis have developed mutations in the ethA gene, sparing them from the toxic effects of the transformed ethionamide.

It doesn't degrade as quickly during storage and is released only after it's been activated by enzymes in the guinea pig's digestive system.

Not exact matches

In addition, sprouting boosts their nutritional profile by increasing vitamins and micronutrients and activating digestive enzymes.

Whole foods work synergistically by providing the cofactors and enzymes that many nutrients require to be activated and absorbed.

The researchers believe resveratrol confers its effects by activating the enzyme SIRT1, which is known to play a part in life extension.

This enzyme appears to be distinct from two other adenylate cyclases present in the same tissue, which are activated by dopamine and by 5 - hydroxytryptamine, respectively.

By removing an attached string of amino acids, the enzyme activates hormones such as insulin and two hormones that may play a role in obesity — glucagonlike peptide 1 and melanocortin - stimulating hormone.

The study, «AKR1B1 promotes basal - like breast cancer progression by a positive feedback loop that activates the EMT program,» which has been published in The Journal of Experimental Medicine, suggests that an inhibitor of this enzyme currently used to treat diabetes patients could be an effective therapy for this frequently deadly form of cancer.

In a healthy mother, this enzyme is activated by hormones like insulin and insulin - growth factors (IGFs), kick - starting a relay race within cells which stimulates nutrient uptake and, as a result, normal growth and metabolic function.

They found that KIF1B - β affects the cells» power stations, the mitochondria, by activating an enzyme named calcineurin.

Melittin subversively makes TRPV1 channels open by activating other enzymes that act just like those inflammatory compounds.

CLPX is a gene that controls mitochondrial unfoldase, an enzyme that carries out a balancing step in actively unfolds selected proteins for «protein quality control» during heme biosynthesis by catalytically activating the rate - limiting step enzyme, ALAS, or degrading ALAS protein.

The research team led by Ville Kaila and Michael Groll, Professor of Biochemistry at the Technical University of Munich, have, for the first time, deciphered the mechanism of the enzyme aspoquinolone J (AsqJ), a dioxygenase that activates carbon bonds with oxygen.

In a series of cell - based studies, they showed that it both blocked a family of iron - containing, oxygen - sensing enzymes called hypoxia - inducible factor prolyl - hydroxylases (HIF - PHD) and, critically, protected neurons by activating genes that protect them from oxidative stress.

A potential drug target would have to be found within the cancer - causing pathways activated by Rac1b, since the enzyme is difficult to target because it is involved in many normal biological processes, Dr. Radisky says.

They then used light to turn on a chemical process that activates enzymes that naturally allow yeast to grow and multiply by eating glucose and secreting ethanol.

Current treatments against the tuberculosis - causing bacteria include prodrugs, such as ethionamide, which are activated by a bacterial enzyme.

The signal, which has been known for a long time, involves an enzyme present in every cell of the body, called PKR, which remains silent unless it is activated by a specific RNA structure thought to occur only in RNA made by viruses.

Researchers have linked increased resistance to bacterial pneumonia in female mice to an enzyme activated by the female sex hormone estrogen.

Previous work by Freeman's lab identified another enzyme, a gene called SARM, which was the first shown to activate a process that causes axons to disintegrate when damaged.

Chemically modified inhibitors of the COX - 2 enzyme relieve anxiety behaviors in mice by activating natural «endocannabinoids» without gastrointestinal side effects, Vanderbilt University scientists will report next week.

They also have found that chemically modified inhibitors of the COX - 2 enzyme they developed relieve anxiety behaviors in mice by activating natural «endocannabinoids» without gastrointestinal side effects.

«For example, restoring the lost enzymes in the two metabolic pathways might slow tumor progression and reduce aggressiveness by inactivating oncogenic kinases and activating immune responses,» says Chakravarti, who holds the Max Morehouse Chair in Cancer Research.

«The company produced a pro-drug, which must be activated by a naturally occurring enzyme in human leukocytes before it can become effective.

Now in a study published in the journal Scientific Reports, Alexander Zaika, Ph.D. and coworkers show that DNA damage in the esophageal cells caused by acidic bile reflux (BA / A) activates enzymes called NADPH oxidases in the mitochondria, the cell's power house, to release highly reactive - oxygen species (ROS).

Using biochemical methods, Gack found that an enzyme called TRIM25 activates RIG - I by tagging it with a protein called ubiquitin.

Molecular cloning has demonstrated that dunce codes for the enzyme, cAMP phosphodiesterase; rutabaga codes for adenylyl cyclase; DCO codes for the catalytic subunit of protein kinase A, and CREB a transcription factor that is phosphorylated and activated by protein kinase A.

Giulia Pontarollo and colleagues at the University of Padua provide new support for this hypothesis in their report in the Journal of Biological Chemistry that subtilisin, a serine protease secreted by Bacillus subtilis, is able to activate the human coagulation - promoting enzyme thrombin through a different mechanism than that used by human cells to activate it.

«We figured that if there were going to be mutations that constitutively activated these enzymes, and that would thus be targetable by drugs, the kinase domains would be the ones to go for,» said Vogelstein.

Aug. 5, 2013 — Chemically modified inhibitors of the COX - 2 enzyme relieve anxiety behaviors in mice by activating natural «endocannabinoids» without gastrointestinal side effects, Vanderbilt University scientists will report next week.

Kinases are important enzymes that activate other proteins by adding a phosphate group to them.

Ginger activates an enzyme which is responsible for improved use of cholesterol by our bodies, effectively reducing the levels of bad cholesterol in our body.

Furthermore, the amounts of eNOS in tissue of the heart, and nitrosothiols and nitrite within the blood and also heart tissue, remained high for 7 days after exercise stopped, as opposed to other heart enzymes activated by exercise.

Enzymes are activated by magnesium.

Enzyme Nutrition Multi-Vitamins by Enzymedica are more than a 100 % whole food multi-vitamin: it's Enzyme - Activated Nutrients.

First, there is evidence from human studies that enzyme systems in our cells required for detoxification of cancer - causing substances can be activated by compounds made from glucosinolates found in Brussels sprouts.

In order for this activation to take place, the enzyme methionine adenosyltransferase (MAT, also known as S - adenosyl methionine synthetase) breaks apart ATP to harvest from it a molecule of adenosine and then activates methionine by sticking adenosine onto it.

They do this partly by activating enzymes.

By combining the beta - glucuronidase enzyme with Lyme antigens, the LDI diminishes the abnormally activated TH2 immune system, which is the major cause of symptoms in chronic Lyme disease, but allows the TH1 to take over and effectively attack the Lyme bacteria in the cells.

By activating special detoxifying enzymes, anthocyanins help to metabolize carcinogens.

Four years ago, my acupuncturist put me on a copper - zinc balancing program, but it was only about a year ago that I learned about pyroluria from the Resource Tool Kit in The Mood Cure by Julia Ross, MA.29 Those of us with this condition, affecting 11 percent of the population, produce excessive amounts of a metabolic toxin called pyrroles, which requires vitamin B6 and zinc for detoxification.30 Significantly, this condition is found disproportionately in those with alcoholism, 31 schizophrenia32 and mood disorders.33 It can also produce baffling physical symptoms due to heightened deficiency of these two nutrients, as well as manganese, 34 a nutrient that is crucially needed to activate arginase, 35 the enzyme that converts ammonia to urea for excretion from the body.

The important thing to understand is that LLLT works by activating a very important enzyme known as «cytochrome c oxidase»... which plays a crucial role in healthy metabolism and energy production.

In several clinical trials, berberine effectively stabilized blood sugar by activating a regluatory enzyme known as adenosine monophosphate - activated protein kinase, or AMPK.

And again, that sulphatase enzyme in the gut made by healthy bacteria, really helps to activate, that thyroid hormone really helps to upregulate those D2, D3 enzymes to get your T4 to T3.

It also helps activate enzymes that you need to maintain your metabolism and works as an antioxidant, protecting your cells from damage by harmful free radicals.

-RCB- elevated sodium level within kidneys, either as a result of pathological bottleneck such as reduced number of nephrons, or simply due to heightened intake - or both - may activate pro-inflammatory cytokines and chemokines in proximal tubular cells, may cause oxidative stress by activating ROS - producing NADH oxidase enzymes, or blood vessel constriction by inhibiting kidney arginine transport and nitric oxide synthesis; elevated renal inflammation, oxidative stress and restricted blood flow all can impair the efficacy of sodium excretion, more so combined (if extensive, it can also result in post-natal reduction of nephron units)

Proteolytic enzymes such as papain, bromelain, trypsin and chymotrypsin promote healing by supporting the production of cytokines, activating immune system proteins such as alpha -2-macroglobulins, breaking down fibrinogen and slowing the clotting mechanism (30).

That's the, you know, when your adrenal glands get stimulated by adrenal rush, that little spidey tingly sense you get, that's your sympathetic nervous system and if that response is activated prolonged, it really shuts down digestion, enzyme production, and hydrochloric acid secretion.

HCL (Hydrochloric acid) activates pepsinogen into the enzyme pepsin, which then helps digestion by breaking the bonds linking amino acids, a process known as proteolysis.

A key enzyme in cholesterol biosynthesis is 3 - hydroxy -3-methylglutaryl — CoA reductase (the target for statins), which is activated by insulin, which means that an increase in blood glucose and consequently of insulin levels will lead to increased endogenous cholesterol synthesis.