Sentences with phrase «activated killer cells»

Observations on the systemic administration of autologous lymphokine - activated killer cells and recombinant interleukin - 2 to patients with metastatic cancer.

Not exact matches

In December, SQZ partnered with global pharma firm and cancer treatment leader F. Hoffmann - La Roche in a deal that could be worth $ 500 million or more — a large undisclosed upfront payment, and additional sums when SQZ meets certain milestones — to speed up the development of its technology specifically to inject a person's immune cells with a protein to activate a «killer T» cell response to fight off cancer.

The activating receptor NKp46 is important for keeping the responses of natural killer cells in check.

Next, the HIV - binding end of the protein latches onto those pieces of virus while the CD3 - binding end attaches to a killer T cell, activating it and bringing it close to the helper T cell.

4) Activated killer T cell destroys HIV - infected helper T cell.

3) Protein binds to HIV fragment on helper T cell and CD3 receptor on killer T cell, activating the killer T cell and bringing the two cells close together.

Then you activate the killer T cells with the dendritic - cell vaccine, so now you've got all your smart bombs and your cruise missiles coming in from outside.

Now, the bispecific antibody grabs a killer T cell that has a CD3 receptor and, with its second arm, finds a recently activated cell that has HIV proteins on its surface.

Invariant natural killer T (iNKT) cells are rare helper immune cells that activate these cytotoxic cells when cancers go into hiding.

Sun thinks these particular cytokines may activate killer T cells, which poison tumor cells, as well as macrophages, which gobble them up.

helper T cells (CD4)- a group of T cells that help produce antibodies, activate killer T cells (CD8), and make sure the immune system works smoothly.

killer T cells (CD8)- a group of T cells that is activated by helper T cells (CD4) and have the ability to destroy cells infected by foreign invaders (such as viruses).

Klas Kärre, with Rolf Kiessling, reports on experiments suggesting that natural killer cells are inhibited, not activated, by interacting with MHC class I.

David Raulet and Lewis Lanier, separately, show that tumor cells expressing ligands for the natural killer cell activating receptor NKG2D are destroyed by natural killer cells in vivo, establishing a new mechanism for how natural killer cells recognize tumor cells.

David Raulet and colleagues show that the DNA damage response, a kinase cascade induced in early stage cancer cells, induces tumor cells to display ligands that activate natural killer cells and induce tumor cell killing.

Inhibitory signaling blocks activating receptor clustering and induces cytoskeletal retraction in natural killer cells.

Rasmusson I, Ringden O, Sundberg B, Le Blanc K. Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytes or natural killer cells.

25: Radaeva S, Sun R, Jaruga B, Nguyen VT, Tian Z, Gao B. Natural killer cells ameliorate liver fibrosis by killing activated stellate cells in NKG2D - dependent and tumor necrosis factor - related apoptosis - inducing ligand - dependent manners.

In the vacation subnetwork MME is linked to NFIL3, a gene found on activated T cells, natural killer cells and mast cells.

(24 - 28) Dr. Judith Campisi, in fact, has found that activating NKG2D receptors on natural killer (NK) cells engage MHC class I chain - related protein A and B (MICA / B) ligands on senescent cells, leading to their NK - induced apopotsis and subsequent clearance.

The Dotiwala laboratory uses cellular, molecular, biochemical and omics approaches, as well as sophisticated in vivo imaging, to dissect the mechanism by which cell - based immunity (neutrophils, macrophages and killer lymphocytes) is activated in the presence of different pathogenic bacteria, such as intra - and extracellular bacteria, fungi and protozoa.

The IRF3 team will repeat these studies and, for the first time, safeguard the new killer cells from being attacked by HIV when «activated» by removing the CCR5 protein.

This is often enough to halt the infection but the second part of the immune response is adaptive immunity, when dendritic cells activate T lymphocytes and trigger a cascade of immune reactions, such as the formation of antibodies and killer cells that clear the infection from the body and form a memory of the invading pathogen.

Probiotic supplementation has been shown to strengthen the activity of many cytokines — increasing interleukin (IL)-1 β and IL - 18 activates IFN - γ production from T, B, and Natural Killer Cells, which enhances phagocytosis (destruction) of pathogens.

With astragalus root extract and mushroom (reishi & maitake) extracts, it activates your natural killer cells to get rid of any invaders before they have a chance to take root.

, an immune booster that helps activate killer T cells while boosting energy with an adaptogen, is my first lifesaver.

Reishi has been shown to activate several types of human immune cells such as macrophages and natural killer cells.

It does this by activating two important immune cells: macrophages and natural killer (NK) cells.