Sentences with phrase «activated optogenetic»

«Engineers create most efficient red light - activated optogenetic switch for mammalian cells.»

Not exact matches

Using the new science of optogenetics, scientists can activate or shut down neural pathways, altering behavior and heralding a true cure for psychiatric disease.

Once they had identified the «love» circuit, the researchers devised a way to activate it themselves in female voles using a technique called optogenetics.

Discovered by Peter Hegemann in green algae, channelrhodopsin - 2 is the central light - activated channel protein in optogenetics.

This is the most efficient so - called «optogenetic switch» activated by red and far - red light that has been successfully designed and tested in animal cells — and it doesn't require the addition of sensing molecules from outside the cells.

Controlling intracellular membranes, such as vesicles, is a seemingly impossible proposition, but researchers at the Center for Cognition and Sociality within the Institute for Basic Science (IBS) have created an optogenetic process, called «light - activated reversible inhibition by assembled trap of intracellular membranes» (IM - LARIAT) that allows for the observation and control membranes that populate our cells.

Optogenetics has been able to activate single neurons in living animals in milliseconds and reverse the intervention just as rapidly.

The work is part of a growing field called optogenetics, and used light - activated proteins from photosynthetic algae to switch nerve cells on and off.

To test this, they used optogenetic light stimulation over several days to selectively activate the cMPOA neurons that project to the BSTrh in virgin males.

The researchers inserted an optogenetic switch into a group of nerve cells located in the ancient part of the brain called the medulla, allowing them to activate or inactivate the neurons with laser light.

Electrical and chemical activities in the neurons could then be activated or switched off by pulses of light delivered via a fiber - optic cable implanted in each mouse's skull, a technique known as optogenetics.

These manipulations, belonging to optogenetics — a technique extensively studied in Yizhar's lab — enabled the researchers to activate only those amygdala neurons that interact with the cortex, and then to map out the cortical neurons that receive input from these light - sensitive neurons.

To find out if these chemical changes do indeed take place, the researchers first identified a group of engram cells in the hippocampus that, when activated using optogenetic tools, were able to express a memory.

Optogenetics has taken neuroscience by storm in recent years because the technique allows scientists to study the brain conveniently in animals, activating or inhibiting selected groups of neurons at the flip of a switch. Most often, scientists use a fiber optic cable to deliver light into the brain.

The researchers used optogenetics, a means of engineering specific neurons to fire upon light stimulation, to isolate and selectively activate each set of neurons.

The scientists used optogenetics — an innovative research tool that uses light to activate or inhibit select cells in the brain — to stimulate either the go or the stop pathway in mice that were running on a tiny treadmill, while recording neural activity in the brainstem.

Yang Xiang, PhD, assistant professor of neurobiology at University of Massachusetts Medical School, has received a three - year, $ 900,000 grant from the Human Frontiers Science Program to lead an international team of scientists, including Gang Han, PhD, assistant professor of biochemistry & molecular pharmacology, in the development and implementation of a new optogenetic platform that can remotely activate neurons inside a free - moving organism.

March 12, 2015 Optogenetics without the genetics Light can be used to activate normal, non-genetically modified neurons through the use of targeted gold nanoparticles, report scientists from the University of Chicago and the University of Illinois at Chicago.