Sentences with phrase «activated wild type»
In the study, published in Cell Reports, the University of Kentucky's Vivek Rangnekar and his colleagues activated wild type p53 in normal cells to trigger cell death in the p53 - deficient cancer cells.
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Activated, wild type B cells from female mice tightly localize Xist RNA at their inactive X chromosomes (left), whereas Xist RNA becomes dispersed throughout the entire nucleus when YY1 is deleted (right).
Cellular distribution and functions of wild - type and constitutively activated Dictyostelium PakB.
Interestingly, our data revealed that at a higher dosage (2 μg / well), the wild - type DDX3 and mutant DDX3 / AAA up - regulated the activity of p21waf1 / cip1 promoter ∼ 12-fold whereas the DDX3 / DQAD mutant only activated the p21waf1 / cip1 promoter activity ∼ 5-fold (Supplementary Fig.
«Recent data have described a correlation between the levels of activated Notch1 and poor prognosis in a cohort of NSCLC patients, but only in patients with wild type p53,» a group that they wrote represents about half of all NSCLC patients.