Not exact matches
When we watch someone else, our
brain is
activated in the same way that the
brain of the person you are observing is
activated, effectively through what is called «mirror
neurons.»
The bacteria, when injected into mice,
activate a set of serotonin - releasing
neurons in the
brain — the same nerves targeted by Prozac.
The team also looked at the mouse
brains to see which
neurons, if any, were
activated after the bacterial injection.
The
brain (specifically, the olfactory bulb and olfactory cortex) then looks at the combination of sensory
neurons activated at any given time and interprets that pattern in the context of previous patterns that have been experienced and other kinds of available information.
The actual
neurons in the
brain, they realized, only become a factor in the organ's overall computational process when they are
activated.
Instead of
activating a small sphere of surrounding
neurons as expected, the electrodes caused sparse strings of
neurons to fire across the
brain.
The finding suggests that
brain surgeons and the designers of neural prosthetics have a much smaller margin of error than previously thought — shifting an electrode even slightly could
activate an entirely different set of
neurons.
Instead of a small number of large, powerful processors working continuously, the
brain contains billions of relatively slow, small processors — its
neurons — which consume power only when
activated.
Previous research has shown that a network of mirror
neurons in the
brain is
activated when we watch people move in familiar ways — we mentally rehearse their actions as if we were performing them ourselves.
As the name implies, the technique involves electrical currents flowing through electrodes in random pulses,
activating neurons in multiple
brain areas.
Potentially explaining why even healthy
brains don't function well with age, Salk researchers have discovered that genes that are switched on early in
brain development to sever connections between
neurons as the
brain fine - tunes, are again
activated in aging neuronal support cells called astrocytes.
«If the sounds of the word had influence in this part of the
brain we would expect to see that they
activate the same or similar
neurons, but this was not the case — «hair» and «hare» looked just as different as «hair» and «soup.»»
Yet the pons, an area of the
brain just above the spinal cord, prevents motor
neurons, the controllers of muscles, from
activating movements.
They analyzed the data to determine exactly what was happening in the ventral sensory motor cortex (vSMC)-- how that area of the
brain region was laid out, and in what order the
neurons activated.
The team of international scientists had discovered that by
activating Nurr1, a class of proteins found in the
brain, it protects the
brain's ability to generate dopamine
neurons.
The inhibitory
neurons they identified appear to control whether touch
activates the excitatory
neurons to send a pain signal to the
brain.
In a famous set of experiments in human subjects in 2005, neuroscientist Rodrigo Quian Quiroga found that pictures of actor Jennifer Aniston
activated a single
brain cell in the hippocampus region — the so - called Jennifer Aniston
neuron.
By recording volume variations in the blood vessels irrigating the different
brain structures, it is therefore possible to determine the location of
activated neurons.
Neuroscientists believe that memory forms when
neurons in these key
brain structures are simultaneously
activated by glutamate and an electrical pulse, a result of everyday sensory experience.
She did so by
activating neurons in a specific region of the hypothalamus, deep in the center of the
brain.
With help from collaborators at the Allen Institute for
Brain Science in Seattle, the team applied a variant of the c - fos method that distinguishes the
neurons activated in two different, successive behavioral encounters.
These results indicated that, surprisingly, many
brain regions surveyed contained separate but intermingled populations of
neurons activated during fighting versus mating, with only a small degree (about 20 percent) of overlap.
Interestingly, these rats were still motivated to drink sugar water, indicating that the researchers had successfully targeted only alcohol -
activated neurons, not the
brain's overall reward system.
Her research suggested that T cells can also send signals that
activate the
brain's resident immune cells, microglia and blood - borne macrophages, telling them to protect the injured
neurons from toxins released by the injury.
In the basal ganglia — a complex system of
neurons in the
brain responsible for, among other things, procedural learning — Bottjer and Achiro were able to isolate two different types of
neurons in young songbirds: ones that were
activated only when the birds heard themselves singing, and others that were
activated only when the birds heard the songs of adult birds that they were trying to imitate.
The
brain chemical, or neurotransmitter, is glutamate, the most important excitatory neurotransmitter in the
brain, which essentially means it is passed between
neurons to help one
activate the next.
The researchers inserted an optogenetic switch into a group of nerve cells located in the ancient part of the
brain called the medulla, allowing them to
activate or inactivate the
neurons with laser light.
The findings open up new avenues of research into exactly how the
brain controls eating, and suggest that drugs designed to
activate or inhibit
neurons in the DRN could be effective in treating obesity and preventing its related disorders, such as diabetes and hypertension.
When they mutated neuregulin 3 in
neurons that help
activate the
brain — called pyramidal
neurons — the genetically modified mice displayed behavior consistent with schizophrenia.
Previous studies from George's lab had shown that nicotine
activates certain «reward»
neurons in the
brain — giving positive reinforcement to keep smoking.
In an effort to disentangle the roles that different regions of the
brain play in complex problem solving, researchers have traced the networks of
neurons activated in chess players»
brains as they contemplate their next move.
Eating fewer calories may work by depleting a
brain chemical called kynurenic acid, which in turn
activates neurons involved in learning.
These problems are caused by a type of white blood cells called T cells that, after becoming
activated, find their way into the
brain and attack the protective covering — myelin — of
neurons in the
brain and spinal cord, causing inflammation and damage to the central nervous system.
By implanting electrodes into the somatosensory cortex — the
brain region that registers touch — Brecht and his team have identified the
neurons that
activate physical responses to tickling (Science, doi.org/bsxv).
«We wanted to
activate with magnetism a specific set of
neurons in the
brain responsible for pleasure,» Güler said.
Here, in samples of mouse hypothalamus — the
brain center that detects and regulates internal temperature — Kun Song and colleagues identified
neurons that were uniquely
activated in response to warming at temperatures above the physiological set point of 37 °C.
This method allows specific targeting within the
brain and tight control of the timing of
activating or inactivating
neurons.
Memory researchers have previously speculated that somewhere in the
brain network is a population of
neurons that are
activated during the process of acquiring a memory, causing enduring physical or chemical changes.
These hormones, in turn,
activate a host of
neurons in the
brain's hypothalamus — the body's energy control center.
When they shone a light on the
brain, only the
neurons containing the light - sensitive proteins became
activated.
Here, we first demonstrated that Acks signals were detected in the MBs, especially in the Class II KCs of workers at 30 or 60 min after the bee ball formation, and
neurons located in a restricted area between the DLs and the OLs of workers at 60 min whereas they were scarcely detected at 0 min (Figure 4, Figure S3, and Figure S4), strongly suggesting that these
neurons are highly
activated in the
brains of workers involved in forming the hot defensive bee ball.
Optogenetics has taken neuroscience by storm in recent years because the technique allows scientists to study the
brain conveniently in animals,
activating or inhibiting selected groups of
neurons at the flip of a switch. Most often, scientists use a fiber optic cable to deliver light into the
brain.
• Keeping abnormal proteins from building up and potentially shutting down major organs (heart, liver and nervous system, to name a few) • Protecting the
brain's functions of learning and memory against neurotransmitter toxicity •
Activating or increasing the activity of proteins that promote the initial growth, maintenance and survival of
brain neurons • Enhancing the movement of proteins, lipids and other cell parts through the cytoplasm of cell bodies.
In our
brains, glutamate is a signal that
activates, or excites,
neurons that it lands on.
«But we do know that disruption occurs, and the blood proteins we have found in the
brain are able to
activate the
brain's immune cells and damage
neurons.»
Despite ceasing their compulsive drinking, the animals were still motivated to drink sugar water, which means that the researchers were successful at targeting only alcohol -
activated neurons, and not the overall reward system of the
brain.
When a neural stem cell becomes
activated, it begins a process of cell division that ultimately yields new
neurons that connect to existing
brain circuits.
Abbreviations: Aβ, amyloid β - peptide; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; Ambra1,
activating molecule in Beclin -1-regulated autophagy; AMPK, AMP -
activated protein kinase; APP, amyloid precursor protein; AR, androgen receptor; Atg, autophagy - related; AV, autophagic vacuole; Bcl, B - cell lymphoma; BH3, Bcl - 2 homology 3; CaMKKβ, Ca2 + - dependent protein kinase kinase β; CHMP2B, charged multivesicular body protein 2B; CMA, chaperone - mediated autophagy; 2 ′ 5 ′ ddA, 2 ′, 5 ′ - dideoxyadenosine; deptor, DEP - domain containing mTOR - interacting protein; DRPLA, dentatorubral pallidoluysian atrophy; 4E - BP1, translation initiation factor 4E - binding protein - 1; Epac, exchange protein directly
activated by cAMP; ER, endoplasmic reticulum; ERK1 / 2, extracellular - signal - regulated kinase 1/2; ESCRT, endosomal sorting complex required for transport; FAD, familial AD; FDA, U.S. Food and Drug Administration; FIP200, focal adhesion kinase family - interacting protein of 200 kDa; FoxO3, forkhead box O3; FTD, frontotemporal dementia; FTD3, FTD linked to chromosome 3; GAP, GTPase -
activating protein; GR, guanidine retinoid; GSK3, glycogen synthase kinase 3; HD, Huntington's disease; hiPSC, human induced pluripotent stem cell; hVps, mammalian vacuolar protein sorting homologue; IKK, inhibitor of nuclear factor κB kinase; IMPase, inositol monophosphatase; IP3R, Ins (1,4,5) P3 receptor; I1R, imidazoline - 1 receptor; JNK1, c - Jun N - terminal kinase 1; LC3, light chain 3; LD, Lafora disease; L - NAME, NG - nitro - L - arginine methyl ester; LRRK2, leucine - rich repeat kinase 2; MIPS, myo - inositol -1-phosphate synthase; mLST8, mammalian lethal with SEC13 protein 8; MND, motor
neuron disease; mTOR, mammalian target of rapamycin; mTORC, mTOR complex; MVB, multivesicular body; NAC, N - acetylcysteine; NBR1, neighbour of BRCA1 gene 1; NOS, nitric oxide synthase; p70S6K, ribosomal protein S6 kinase - 1; PD, Parkinson's disease; PDK1, phosphoinositide - dependent kinase 1; PE, phosphatidylethanolamine; PI3K, phosphoinositide 3 - kinase; PI3KC1a, class Ia PI3K; PI3KC3, class III PI3K; PI3KK, PI3K - related protein kinase; PINK1, PTEN - induced kinase 1; PKA, protein kinase A; PLC, phospholipase C; polyQ, polyglutamine; PS, presenilin; PTEN, phosphatase and tensin homologue deleted from chromosome 10; Rag, Ras - related GTP - binding protein; raptor, regulatory - associated protein of mTOR; Rheb, Ras homologue enriched in
brain; rictor, rapamycin - insensitive companion of mTOR; SBMA, spinobulbar muscular atrophy; SCA, spinocerebellar ataxia; SLC, solute carrier; SMER, small - molecule enhancer of rapamycin; SMIR, small - molecule inhibitor of rapamycin; SNARE, N - ethylmaleimide - sensitive factor - attachment protein receptor; SOD1, copper / zinc superoxide dismutase 1; TFEB, transcription factor EB; TOR, target of rapamycin; TSC, tuberous sclerosis complex; ULK1, UNC -51-like kinase 1; UVRAG, UV irradiation resistance - associated gene; VAMP, vesicle - associated membrane protein; v - ATPase, vacuolar H + - ATPase; Vps, vacuolar protein sorting
Using lasers and computers, the tool can precisely target and
activate certain
neurons in the thorax and
brain of the fruit fly Drosophila melanogaster raising its temperature and stirring up its courtship behaviors.
Xiang and Han believe these nanoparticles, tuned to emit blue light, can be inserted into the
brain and used as a substitute for traditional fiber optics to wirelessly
activate neurons in animals.