Sentences with phrase «activates immune receptor»

Not exact matches

When ICZ binds to and activates the Aryl hydrocarbon receptor (AHR) in the intestinal lining, it aids in maintaining a healthy balance in the gut flora and immune surveillance, and enhances host barrier function, according to the researchers.

These immune receptors are essential for eliciting inflammatory and anti-microbial responses and for activating an adaptive immune response.

When the researchers added a little of this bacterial byproduct to the mix, Fel d 1 activated a specific immune receptor on cells, called Toll - like receptor 4 (TLR4).

«What we think happens is that the bacteria activate immune cells, which release chemicals called cytokines that then act on receptors on the sensory nerves to increase their activity,» he says.

THC activated two types of cannabinoid receptor on immune cells, called CB1 and CB2.

Current thinking regarding type III hypersensitivity is that immune cells within tissues sense the presence of these immune complexes (ICs) through specific receptor molecules and release inflammatory factors called cytokines that activate the endothelial cells lining adjacent blood vessels to promote the recruitment of neutrophils.

Bruce Beutler of the Scripps Research Institute in San Diego, California, completed the puzzle by showing how the Toll - like receptors activate the innate immune system.

The nanoparticle, the vector for IL - 2, carries the substance to the receptors in cancer cells, then saturates them and kills them, besides generating an immune T cells bridge (in charge of activating the immune response of the organism).

The researchers posit the explanation that kynurenic acid activated the cell receptor GPR35, which is found in both fat cells and immune cells.

These receptors recognize constituent substances of bacteria such as surface proteins and then activate the immune system.

Microbes that cause diseases like HIV, malaria, and hepatitis C exploit and often activate the same checkpoint pathways — cell surface receptors such as CTLA4 and PD - 1 — to slow immune cells and prevent their elimination by the host.

Candidates for lipid - metabolite sensors of inflammatory status are members of the family of the peroxisome proliferator - activated receptors (PPARs), which are expressed in many immune cells.

These results suggest that immune complex - triggered inflammation is initiated by cell bound Fc receptors and is then amplified by cellular mediators and activated complement.

Beutler and Hoffmann discovered receptor proteins that can recognize microorganisms and activate innate immunity, the first step in the body's immune response.

PD - 1 is a receptor present on activated T cells, which mediates immunosuppression primarily in peripheral tissues, where PD - 1 ligands, PD - L1 and PD - L2 share an immunosuppressive activity and may be produced by either tumor cells or stromal / tumor - infiltrating immune cells.

In 2008, several CRI investigators were part of a multi-institutional preclinical study showing that treatment with the immune activating molecule interleukin 15 (IL - 15), when complexed with its receptor, could trigger rapid regression of established pancreatic cancers and significantly prolong survival.

Now, a drug that activates CB2 receptors on immune cells has been shown to improve symptoms and survival in HD mice - with interesting implications for the immune system as a target for HD therapies.

He is looking to find whether activating the receptor — transient receptor potential vanilloid - 1, or TRPV1 — on the immune cells that rush to the ailing brain, can reduce the lingering inflammation associated with problems like poor cognition and depression in the aftermath of a TBI.

There is a receptor in our intestines activated by phytonutrients in cruciferous vegetables that boosts immune function (the aryl hydrocarbon [Ah] receptor).