Moreover, disease - causing variants in DNA often do not act directly, but by
activating nearby genes.
The problem is that they insert genes at random locations in the genome, as well as inserting regulatory sequences that can sometimes
activate nearby genes and trigger cancer.
Not exact matches
Cells growing into the wound had 12
genes that were
activated much more or much less than
nearby cells sitting idly on the sidelines.
Then p300 modifies
nearby chromatin with a chemical tag called acetylation, somehow releasing the inhibitory chromatin structure to
activate a
gene.