Sentences with phrase «activation of amp»

Berberine improves insulin signal transduction by stimulating glucose intake via the activation of the AMP - activated protein kinase pathway.

Recent evidence suggested that Aβ42 can trigger activation of AMP - activated Kinase (AMPK) and that AMPK activation is increased in the brain of AD patients.

LKB1 acts as a key regulator of cell polarity as well as energy metabolism partly through the activation of the AMP - activated protein kinase (AMPK), a sensor that adapts energy supply to the nutrient demands of cells facing situations of metabolic stress.

New link between AnxA1 / FPR2 system and activation of AMP - activated protein kinase Thomas Gobbetti (Queen Mary University, London, United Kingdom)

Not exact matches

The mechanism of presynaptic facilitation, therefore, may include activation of one or more serotonergic neurons, which enhance the release of a neurotransmitter by increasing the intracellular concentration of cyclic AMP in the terminals of the sensory neurons.

Activation of cyclic AMP signaling leads to different pathway alterations in lesions of the adrenal cortex caused by germline PRKAR1A defects versus those due to somatic GNAS mutations.

ant Temp Tachometer Trip Odometer And Trip Computer, Engine: 2.4 L Gdi 4 - Cylinder Seats Premium Cloth Seat Upholstery, Bucket Front Seats, Fold Forward Seatback Rear Seats, Rear Seats Center Armrest, Seatback Storage: 2, Front Center Armrest And Rear Center Armrest, 60 - 40 Folding Bench Front Facing Fold Forward Seatback Rear Seat, Front Bucket Seats - Inc: Multi-Adjustable Driver's Seat W / Adjustable Lumbar Support 6 - Way Manual Passenger Seat W / Height Adjust Seatback Pockets And Energy Absorbing Front Seats Doors Remote Power Door Locks, Metal - Look Door Trim, Door Reinforcement: Side - Impact Door Beam, Door Pockets: Driver, Left Rear Passenger Door Type: Conventional, Rear Door Type: Trunk, Right Rear Passenger Door Type: Conventional, 4 Door, Body - Colored Door Handles, Radio: Am / Fm / Siriusxm / Cd / Mp3 Display Audio - Inc: Iphone / Usb And Auxiliary Jacks 7 - Inch Color Touchscreen Apple Car Play Android Auto Hd Radio Technology W / Multicasting Integrated Bluetooth W / Phonebook Transfer And 6 Speakers (2 Front - Door - Mounted 2 Tweeters And 2 Rear), Carpet Floor Trim And Carpet Trunk Lid / Rear Cargo Door Trim, Cloth Door Trim Insert, Instrument Panel Covered Bin Driver / Passenger And Rear Door Bins, Remote Keyless Entry W / Integrated Key Transmitter 2 Door Curb / Courtesy Illuminated Entry Illuminated Ignition Switch And Panic Button, Interior Trim - Inc: Metal - Look Instrument Panel Insert Metal - Look Door Panel Insert And Metal - Look Interior Accents, Power Door Locks W / Autolock Feature Wheels 4 - Wheel Abs Brakes, Wheel Diameter: 16, Wheel Width: 6.5, Tire Pressure Monitoring System: Tire Specific, Steel Spare Wheel Rim, Spare Tire Mount Location: Inside Under Cargo, Tires: Width: 205 Mm, Tires: Profile: 65, Tires: Speed Rating: H, Diameter Of Tires: 16.0, Type Of Tires: As, Tires: Prefix: P, 4 - Wheel Disc Brakes W / 4 - Wheel Abs Front Vented Discs Brake Assist And Hill Hold Control, Front - Wheel Drive, Tire Specific Low Tire Pressure Warning Mirrors Power Remote W / Tilt Down Driver Mirror Adjustment, Heated Driver Mirror, Heated Passenger Mirror, Power Remote W / Tilt Down Passenger Mirror Adjustment, Dual Reverse Tilt Mirrors, Dual Illuminated Vanity Mirrors, Apple Carplay & Android Auto Mirroring, Body - Colored Power W / Tilt Down Heated Side Mirrors W / Convex Spotter And Manual Folding, Day - Night Rearview Mirror, Driver And Passenger Visor Vanity Mirrors W / Driver And Passenger Illumination Air Interior Air Filtration, Manual Front Air Conditioning, Air Filtration, Manual Air Conditioning Trim Urethane Shift Knob Trim, Metal - Look Dash Trim, Chrome Side Windows Trim And Black Front Windshield Trim Steering Cruise Controls On Steering Wheel, Urethane Steering Wheel Trim, Audio Controls On Steering Wheel, Tilt And Telescopic Steering Wheel, Speed - Proportional Electric Power Steering, Manual Tilt / Telescoping Steering Column, Cruise Control W / Steering Wheel Controls, Radio W / Clock Speed Compensated Volume Control Steering Wheel Controls Voice Activation And Radio Data System, Electric Power - Assist Speed - Sensing Steering Entertainment Bluetooth Wireless Phone Connectivity, Digital Audio Input, In - Dash Single Cd Player, Audio System Memory Card Slot, Mp3 Player, Siriusxm Am / Fm / Hd / Satellite Radio, Radio Data System, Speed Sensitive Audio Volume Control, Total Number Of Speakers: 6, Video Monitor Location: Front, Siriusxm Satellite Radio Fuel Fuel Consumption: City: 25 Mpg, Fuel Consumption: Highway: 38 Mpg, Fuel Type: Regular Unleaded, Fuel Capacity: 18.5 Gal., Instrumentation: Low Fuel Level, Remote Releases - Inc: Power Cargo Access And Power Fuel Dimensions Max Cargo Capacity: 16 Cu.Ft., Curb Weight: 3, Gross Vehicle Weight: 4, Overall Length: 191.1, Overall Width: 73.4, Overall Height: 58.1, Wheelbase: 110.4, Front Head Room: 40.4, Rear Head Room: 38.0, Front Leg Room: 45.5, Rear Leg Room: 35.6, Front Shoulder Room: 57.9, Rear Shoulder Room: 56.5, Front Hip Room: 55.3, Rear Hip Room: 56.1, Outboard Front Lap And Shoulder Safety Belts - Inc: Rear Center 3 Point Height Adjusters And Pretensioners Lights Privacy Glass: Light, Daytime Running Lights, Front And Rear Reading Lights, Remote Activated Exterior Entry Lights, Cargo Area Light, Headlights Off Auto Delay, Dusk Sensing Headlights, Halogen Projector Beam Headlights, Light Tinted Glass, Perimeter / Approach Lights, Cargo Space Lights, Front And Rear Map Lights, Fade - To - Off Interior Lighting Airbags 1St And 2Nd Row Curtain Head Airbags, Passenger Airbag, Side Airbag, Driver Knee Airbags, Driver Airbag, Curtain 1St And 2Nd Row Airbags, Airbag Occupancy Sensor, Dual Stage Driver And Passenger Seat - Mounted Side Airbags, Dual Stage Driver And Passenger Front Airbags, Driver Knee Airbag Suspension Suspension Class: Regular, Independent Front Suspension Classification, Strut Front Suspension, Four - Wheel Independent Suspension, Independent Rear Suspension, Multi-Link Rear Suspension, Front And Rear Suspension Stabilizer Bars, Multi-Link Rear Suspension W / Coil Springs, Strut Front Suspension W / Coil Springs Features Power Windows, Cruise Control, Front Ventilated Disc Brakes, Rear Spoiler: Lip, Braking Assist, Abs And Driveline Traction Control, Stability Control, Silver Aluminum Rims, Trip Computer, External Temperature Display, Tachometer, Manufacturer's 0 - 60Mph Acceleration Time (Seconds): 8.1 S, Blue Link, Power Remote Trunk Release, Anti-Theft Alarm System, Rear Bench, Vehicle Emissions: Ulev Ii, Clock: In - Dash, Coil Front Spring, Regular Front Stabilizer Bar, Coil Rear Spring, Rear Stabilizer Bar: Regular, Variable Intermittent Front Wipers, Metal - Look Grille, Center Console: Full With Covered Storage, Overhead Console: Mini With Storage, 252 Lbs., 497 Lbs., Three 12V Dc Power Outlets, Transmission Hill Holder, Seatbelt Pretensioners: Front, Rear Center Seatbelt: 3 - Point Belt, Cupholders: Front And Rear, Passenger And Rear, Body - Colored Bumpers, Window Grid And Roof Mount Antenna, Selective Service Internet Access, Manual Child Safety Locks, Rear View Camera, 1 Usb Port, Lip Spoiler, Trunk Rear Cargo Access, Body - Colored Rear Bumper, Fixed Rear Window W / Defroster, Fully Automatic Projector Beam Halogen Daytime Running Headlamps W / Delay - Off, Speed Sensitive Variable Intermittent Wipers, Fully Galvanized Steel Panels, Clearcoat Paint, Body - Colored Front Bumper, Front Windshield - Inc: Sun Visor Strip, Analog Display, Outside Temp Gauge, Manual Adjustable Front Head Restraints And Manual Adjustable Rear Head Restraints, Valet Function, Perimeter Alarm, Full Carpet Floor Covering, Full Floor Console W / Covered Storage Mini Overhead Console W / Storage And 3 12V Dc Power Outlets, 3 12V Dc Power Outlets, Power Rear Windows, Hvac - Inc: Underseat Ducts, Redundant Digital Speedometer, Systems Monitor, Illuminated Locking Glove Box, Driver Foot Rest, Full Cloth Headliner, Power 1St Row Windows W / Driver 1 - Touch Up / Down, Rear Cupholder, Fob Controls - Inc: Trunk / Hatch / Tailgate, Front Cupholder, Urethane Gear Shift Knob, Delayed Accessory Power, Wireless Streaming, 2.89 Axle Ratio, 80 - Amp / Hr 640Cca Maintenance - Free Battery W / Run Down Protection, 150 Amp Alternator, Transmission W / Driver Selectable Mode, Front And Rear Anti-Roll Bars, Single Stainless Steel Exhaust W / Chrome Tailpipe Finisher, Gas - Pressurized Shock Absorbers, 4497 # Gvwr, Transmission: 6 - Speed Automatic W / Shiftronic - Inc: Od Lock - Up Torque Converter Shift Lock And Shiftronic Manual Shift Mode, Back - Up Camera, Blue Link Emergency S.O.S, Electronic Stability Control (Esc), Rear Child Safety Locks, Side Impact Beams

* Trailer Tow Group * (originally: $ 795.00) 3.52 final drive ratio; 7 and 4 pin wiring harness; Auxiliary transmission oil cooler; Class III receiver hitch; Full size spare tire; Trailer tow wiring harness; Note: Heavy duty engine cooling is included with 3.2 L V6 24V VVT Engine w / ESS - Engine Oil Cooler - Auxilliary Transmission Cooler: auxiliary transmission fluid cooler - Consumer Generic Feature 0: Towing Hitch - Spare Tire Mount Location: inside - Spare Tire Size: fullsize non-matching - Final Drive Ratio: 3.52 - Trailer Wiring - Trailer Hitch * 3.2 L V6 24V VVT Engine W / ESS * (originally: $ 1745.00) 3.25 final drive ratio; 700 amp maintenance free battery; Dual bright exhaust tips; Engine oil cooler; Stop - start multiple VSM system - Engine Auto Stop / start - Engine Oil Cooler - Consumer Generic Feature 0: Upgraded Engine - Final Drive Ratio: 3.25 * Full Size Spare Tire (Fleet) * (originally: $ 100.00)- Spare Tire Size: fullsize non-matching - Spare Tire Mount Location: inside * 9 - Speed 948TE 4WD Automatic Transmission * (originally: $ 1095.00) Active Drive II badge; Auxiliary transmission oil cooler; Electronic range select; Hill descent control; Jeep Active Drive II; Off road suspension - Suspension Class: heavy duty - Descent Control - Auxilliary Transmission Cooler: auxiliary transmission fluid cooler - Consumer Generic Feature 0: AWD / 4WD - 4wd Type: on demand - Locking Hubs: automatic - Transfer Case: electronic hi - lo gear selection - Driven Wheels: four wheel drive * Uconnect 8.4 AN * (originally: $ 945.00) AM / FM stereo with HD radio; SiriusXM Radio; Hard disc drive; 8.4 touchscreen display; GPS antenna input; GPS navigation; Integrated voice command with Bluetooth; Uconnect Access with 6 month trial (registration required)- Navigation System: navigation with voice activation - Consumer Generic Feature 0: Bluetooth - Consumer Generic Feature 1: Mobile Internet - Consumer Generic Feature 2: Navigation - Satellite Communications: Uconnect Access - Months Of Free Satellite Communications Service: 12 - Mobile Router - Bluetooth - Phone Controls On Steering WheelThis vehicle came with a free satellite radio subscription when it was new.

* Power Front / Fixed Rear Full Sunroof * (originally: $ 1755.00) CommandView dual pane glass roof with power sliding front glass over 1st row seats, and fixed rear glass over 2nd row seats with power sunshade in rear - Consumer Generic Feature 0: Sunroof / Moonroof - One Touch Power Sunroof: one - touch power sunroof - 2nd Row Sunroof: fixed glass - Sunroof: power glass * 9 Amplified Speakers W / Subwoofer * (originally: $ 595.00) * 3.2 L V6 24V VVT Engine W / ESS * (originally: $ 1745.00) 700 amp maintenance free battery; Dual bright exhaust tips; Engine oil cooler; Stop - start multiple VSM system - Engine Auto Stop / start - Engine Oil Cooler - Consumer Generic Feature 0: Upgraded Engine * Uconnect 8.4 NAV * (originally: $ 1195.00) AM / FM stereo; Uconnect Access with 1 - year trial (registration required); SiriusXM traffic with 5 - years of included service; SiriusXM Travel Link with 5 - years of included service; 8.4 touchscreen display; GPS antenna input; GPS navigation; HD radio; Integrated voice command with Bluetooth; SiriusXM satellite radio - Navigation System: navigation with voice activation - Real Time Traffic - Consumer Generic Feature 0: Bluetooth - Consumer Generic Feature 1: Mobile Internet - Consumer Generic Feature 2: Navigation - Consumer Generic Feature 3: USB Inputs - Consumer Generic Feature 4: Aux Audio Inputs - Satellite Communications: Uconnect Access - Months Of Free Satellite Communications Service: 12 - Mobile Router - Bluetooth - Phone Controls On Steering Wheel * 9 - Speed 948TE 4WD Automatic Transmission * (originally: $ 1205.00) Active Drive II badge; Auxiliary transmission oil cooler; Electronic range select; Hill descent control; Jeep Active Drive II; Off road suspension; Note: 3.52 final drive ratio is included with 3.2 L V6 24V VVT Engine w / ESS - Suspension Class: heavy duty - Descent Control - Auxilliary Transmission Cooler: auxiliary transmission fluid cooler - Consumer Generic Feature 0: AWD / 4WD - Final Drive Ratio: 3.52 - 4wd Type: on demand - Locking Hubs: automatic - Transfer Case: electronic hi - lo gear selection - Driven Wheels: four wheel drive * Trailer Tow Group * (originally: $ 795.00) 3.52 final drive ratio; 7 and 4 pin wiring harness; Auxiliary transmission oil cooler; Class III receiver hitch; Full size spare tire; Trailer tow wiring harness; Note: Heavy duty engine cooling is included with 3.2 L V6 24V VVT Engine w / ESS - Engine Oil Cooler - Auxilliary Transmission Cooler: auxiliary transmission fluid cooler - Consumer Generic Feature 0: Towing Hitch - Spare Tire Mount Location: inside - Spare Tire Size: fullsize non-matching - Final Drive Ratio: 3.52 - Trailer Wiring - Trailer HitchThis vehicle came with a free satellite radio subscription when it was neof included service; SiriusXM Travel Link with 5 - years of included service; 8.4 touchscreen display; GPS antenna input; GPS navigation; HD radio; Integrated voice command with Bluetooth; SiriusXM satellite radio - Navigation System: navigation with voice activation - Real Time Traffic - Consumer Generic Feature 0: Bluetooth - Consumer Generic Feature 1: Mobile Internet - Consumer Generic Feature 2: Navigation - Consumer Generic Feature 3: USB Inputs - Consumer Generic Feature 4: Aux Audio Inputs - Satellite Communications: Uconnect Access - Months Of Free Satellite Communications Service: 12 - Mobile Router - Bluetooth - Phone Controls On Steering Wheel * 9 - Speed 948TE 4WD Automatic Transmission * (originally: $ 1205.00) Active Drive II badge; Auxiliary transmission oil cooler; Electronic range select; Hill descent control; Jeep Active Drive II; Off road suspension; Note: 3.52 final drive ratio is included with 3.2 L V6 24V VVT Engine w / ESS - Suspension Class: heavy duty - Descent Control - Auxilliary Transmission Cooler: auxiliary transmission fluid cooler - Consumer Generic Feature 0: AWD / 4WD - Final Drive Ratio: 3.52 - 4wd Type: on demand - Locking Hubs: automatic - Transfer Case: electronic hi - lo gear selection - Driven Wheels: four wheel drive * Trailer Tow Group * (originally: $ 795.00) 3.52 final drive ratio; 7 and 4 pin wiring harness; Auxiliary transmission oil cooler; Class III receiver hitch; Full size spare tire; Trailer tow wiring harness; Note: Heavy duty engine cooling is included with 3.2 L V6 24V VVT Engine w / ESS - Engine Oil Cooler - Auxilliary Transmission Cooler: auxiliary transmission fluid cooler - Consumer Generic Feature 0: Towing Hitch - Spare Tire Mount Location: inside - Spare Tire Size: fullsize non-matching - Final Drive Ratio: 3.52 - Trailer Wiring - Trailer HitchThis vehicle came with a free satellite radio subscription when it was neof included service; 8.4 touchscreen display; GPS antenna input; GPS navigation; HD radio; Integrated voice command with Bluetooth; SiriusXM satellite radio - Navigation System: navigation with voice activation - Real Time Traffic - Consumer Generic Feature 0: Bluetooth - Consumer Generic Feature 1: Mobile Internet - Consumer Generic Feature 2: Navigation - Consumer Generic Feature 3: USB Inputs - Consumer Generic Feature 4: Aux Audio Inputs - Satellite Communications: Uconnect Access - Months Of Free Satellite Communications Service: 12 - Mobile Router - Bluetooth - Phone Controls On Steering Wheel * 9 - Speed 948TE 4WD Automatic Transmission * (originally: $ 1205.00) Active Drive II badge; Auxiliary transmission oil cooler; Electronic range select; Hill descent control; Jeep Active Drive II; Off road suspension; Note: 3.52 final drive ratio is included with 3.2 L V6 24V VVT Engine w / ESS - Suspension Class: heavy duty - Descent Control - Auxilliary Transmission Cooler: auxiliary transmission fluid cooler - Consumer Generic Feature 0: AWD / 4WD - Final Drive Ratio: 3.52 - 4wd Type: on demand - Locking Hubs: automatic - Transfer Case: electronic hi - lo gear selection - Driven Wheels: four wheel drive * Trailer Tow Group * (originally: $ 795.00) 3.52 final drive ratio; 7 and 4 pin wiring harness; Auxiliary transmission oil cooler; Class III receiver hitch; Full size spare tire; Trailer tow wiring harness; Note: Heavy duty engine cooling is included with 3.2 L V6 24V VVT Engine w / ESS - Engine Oil Cooler - Auxilliary Transmission Cooler: auxiliary transmission fluid cooler - Consumer Generic Feature 0: Towing Hitch - Spare Tire Mount Location: inside - Spare Tire Size: fullsize non-matching - Final Drive Ratio: 3.52 - Trailer Wiring - Trailer HitchThis vehicle came with a free satellite radio subscription when it was neOf Free Satellite Communications Service: 12 - Mobile Router - Bluetooth - Phone Controls On Steering Wheel * 9 - Speed 948TE 4WD Automatic Transmission * (originally: $ 1205.00) Active Drive II badge; Auxiliary transmission oil cooler; Electronic range select; Hill descent control; Jeep Active Drive II; Off road suspension; Note: 3.52 final drive ratio is included with 3.2 L V6 24V VVT Engine w / ESS - Suspension Class: heavy duty - Descent Control - Auxilliary Transmission Cooler: auxiliary transmission fluid cooler - Consumer Generic Feature 0: AWD / 4WD - Final Drive Ratio: 3.52 - 4wd Type: on demand - Locking Hubs: automatic - Transfer Case: electronic hi - lo gear selection - Driven Wheels: four wheel drive * Trailer Tow Group * (originally: $ 795.00) 3.52 final drive ratio; 7 and 4 pin wiring harness; Auxiliary transmission oil cooler; Class III receiver hitch; Full size spare tire; Trailer tow wiring harness; Note: Heavy duty engine cooling is included with 3.2 L V6 24V VVT Engine w / ESS - Engine Oil Cooler - Auxilliary Transmission Cooler: auxiliary transmission fluid cooler - Consumer Generic Feature 0: Towing Hitch - Spare Tire Mount Location: inside - Spare Tire Size: fullsize non-matching - Final Drive Ratio: 3.52 - Trailer Wiring - Trailer HitchThis vehicle came with a free satellite radio subscription when it was new.

, Map pocket, front seatback, driver and front passenger, Mirror, inside rearview manual day / night, Power outlets, 4 auxiliary with covers, 12 - volt includes 1 front of console, 1 in console, 1 in back of console and 1 in cargo area, Rear Vision Camera, Remote Keyless Entry with 2 transmitters, panic button, content theft alarm activation verification and illuminated entry, Seat adjuster front driver power lumbar and power height adjuster, Seat, rear, 2 - way fore / aft adjustment with 60/40 split seatback and 3 - way recline, Seats, Deluxe front bucket, Steering column, tilt and telescopic, Steering wheel controls, mounted audio controls, Steering wheel, comfort grip vinyl with mounted cruise and audio controls,Theft - deterrent system, anti-theft alarm and engine immobilizer, Visors, driver and front passenger illuminated vanity mirrors, Windows, power with Express - Down on all 4 doors, Alternator, 120 amps, Axle, 3.53 final drive ratio (Requires 1LK26 model and (LEA) 2.4 L DOHC 4 - cylinder SIDI engine.)

, LT Interior, Premium Cloth, Map pocket, front seatback, driver and front passenger, Mirror, inside rearview self - dimming, Power outlets, 4 auxiliary with covers, 12 - volt includes 1 front of console, 1 in console, 1 in back of console and 1 in cargo area., Rear Vision Camera, Remote Keyless Entry with 2 transmitters, panic button, content theft alarm activation verification and illuminated entry, Remote vehicle starter system, Seat adjuster front, driver 8 - way power with power lumbar, Seat, rear, 2 - way fore / aft adjustment with 60/40 split seatback and 3 - way recline, Seats, Deluxe front bucket, Seats, heated driver and front passenger, Steering column, tilt and telescopic, Steering wheel controls, mounted audio controls, Steering wheel, leather - wrapped with audio and cruise controls,Theft - deterrent system, anti-theft alarm and engine immobilizer., Visors, driver and front passenger illuminated vanity mirrors, Windows, power with Express - Down on all 4 doors, Alternator, 120 amps, Axle, 3.53 final drive ratio (Requires 1LK26 model and (LEA) 2.4 L DOHC 4 - cylinder SIDI engine.)