Sentences with phrase «active study drug»

Effectiveness will be determined by comparing overall survival and disease - free survival between the participants that receive nivolumab and those that receive placebo (dummy treatment, one that looks like nivolumab but contains no active study drug) following surgery.

Not exact matches

Augros, a professor of philosophy at the Center for Higher Studies in Thornwood, New York, pointed to scientific studies that suggested the active drug in Plan B — levonorgestrel — could function not only as a contraceptive, but as an abortifStudies in Thornwood, New York, pointed to scientific studies that suggested the active drug in Plan B — levonorgestrel — could function not only as a contraceptive, but as an abortifstudies that suggested the active drug in Plan B — levonorgestrel — could function not only as a contraceptive, but as an abortifacient.

Potential subjects were accepted into the study if they had none of the following conditions: severe or symptomatic cardiac disease or hypertension; history of bleeding disorders; chronic history of gastric, intestinal, liver, pancreatic, or renal disease; any portion of the stomach or the intestine removed (other than an appendectomy); history of intestinal obstruction, malabsorption, or use of antacid drugs; cancer (active or use of medications for a history of cancer treatment within the past 5 y); history of chronic alcoholism; a convulsive disorder; or abnormal results in screening blood or urine samples.

less than or equal to lamivudine Acquired Immune Deficiency Syndrome Antiretroviral therapy, usually means 1 - 2 drugs, used in early studies Antiretroviral zidovudine (also known as ZDV) Breastfeeding Baby Friendly Hospital Initiative Breastfeeding and HIV International Transmission Study Combined antiretroviral therapy Centers for Disease Control and Prevention Deoxyribonucleic Acid Exclusive Breastfeeding Enzyme Linked Immunosorbent Assay Food and Agrigulture Organization Fixed dose combination ART, e.g., lamividine, stavudine, and nevirapine Highly Active Antiretroviral Therapy, 3 or more drugs for more effective treatment used in later studies Human Immunodeficiency virus International Atomic Energy Agency Infant feeding Infant and young child feeding Lopinavir cubic millimetre Mother - to - Child Transmission of HIV Non-governmental organization Nevirapine Polymerase Chain Reaction People Living with HIV Prevention of Mother - to - Child Transmission Replacement Feeding Ritonavir Ribonucleic acid, one of the three major macromolecules (along with DNA and proteins) that are essential for all known forms of life single dose NVP United Nations Agencies Joint United Nations Programme on HIV / AIDS United Nations Population Fund United Nations Commissioner for Refugees United Nations Children's Fund U.S. Agency for International Development World Alliance for Breastfeeding Action United Nations World Food Programme World Health Assembly WHO 2010 Guidelines on HIV and infant feeding World Health Organization Zidovudine (same drug as AZT)

According to a report from the National Cancer Institute, a study of 30 randomized studies found that THC (the active ingredient in marijuana) extracts outperformed traditional anti-nausea drugs and helped patients gain weight.

The lab has been particularly active in the development and use of novel behavioral assays that provide a unique approach to the study of drug - behavior interactions.

«One criticism of the PARP drugs is they are not active in patients who have developed resistance to other therapies, but we found veliparib appears to be effective in some platinum - resistant patients with recurrent or persistent disease,» said Robert L. Coleman, MD, lead author of the study and professor and vice chair of clinical research at the University of Texas MD Anderson Cancer Center, Houston.

In a new study, published in International Journal of Pharmaceutics, the researchers show that the extremely porous magnesium carbonate Upsalite may provide a great potential for the development of new drug formulations of active pharmaceutical ingredients with poor aqueous solubility.

«These restrictions also are in conflict with new HCV treatment guidelines from the American Association for the Study of Liver Disease (2015), which explicitly state that active injection drug users should be prioritized for treatment in part because of the risk of transmission to susceptible injection partners.»

... Finally, this study draws attention to the need for large controlled clinical trials to determine if a combination of fall prevention strategies and treatment with bone - active drugs might produce additive benefits on fractures, especially in high - risk populations such as those living in nursing homes.

In the days before fast and cheap molecular biology techniques, she and her colleagues conducted receptor - binding studies, analyzing patients» plasma for signs of the drug or an active (receptor - binding) metabolite.

Diana, whose twin sister died from the same disease, says there are multiple reasons she and John decided to participate in the resveratrol study, and they now know he was assigned to take the active drug.

Sydney's Chris Maher, who is an author on the exercise and drug studies, suspects that the particular kind of exercise you end up choosing may be much less important to solving the problem than simply finding a way to be more active.

And often, the investigative drug will be offered to both the active and the control arms once the study is completed.

During the study, the participants were observed while on highly active antiretroviral therapy, or HAART, which normally consists of three or more drugs and is currently the most common — and most effective — treatment for HIV - positive adults.

A study published on Feb. 6 in the journal Environmental Health Perspectives found that many prescription and over-the-counter drugs and supplements may use phthalates as in active ingredients, but DEHP was not among them.

The research could help other scientists to use cryo - EM in structure - based drug design studies — in which researchers build the best possible drugs starting from a molecule which already binds to the active site of a target protein.

While second - stage results showed no significant differences between participants continuing to receive weekly doses of the active drug, those receiving biweekly doses and those shifted to placebo, Kimball notes that, since it is typical for the severity of HS symptoms to increase and decrease and because the study protocol required treatment discontinuation for participants whose symptoms stopped responding to the drug, larger scale studies will be required to better define the ideal length and frequency of treatment.

And, if heterosexually active, agree to consistently use highly effective contraception per locally accepted standards in addition to a barrier method starting at Screening and throughout the study period and for 180 days after the final study drug administration.

Data on patients receiving active drug in the trial were consistent with a dose - dependent improvement in some parameters of lung function examined in the study, including methacholine challenge test and peak expiratory flow rates, as well as in a biomarker associated with asthma severity and inflammation.

However, I have to point out that the Sanofi - Aventis drug had original construction with another active gene component and study protocol was primarily addressed to the prevention of major amputation.

The study was randomized, double - blind, placebo - controlled, and enrolled 160 patients divided evenly into four groups, three receiving various doses of active drug and one receiving placebo.

An important upside of an open - label extension is that it rewards the volunteers who took part in the original study by giving them guaranteed access to the active drug.

• Patients must have adequate coagulation (international normalized ratio (INR) or prothrombin time (PT), partial thromboplastin time (PTT) ≤ 1.5 times ULN) • Adequate liver function (total bilirubin ≤ 1.5 times the ULN, alanine aminotransferase (ALT) and aspartate aminotransferase (AST) ≤ 2.5 times ULN Exclusion Criteria: • Presence of active / uncontrolled central nervous system involvement • History of clinically significant cardiac disease; uncontrolled hypertension • Left ventricular ejection fraction (LVEF) < 45 % • Allogeneic stem cell transplant within 100 days before first dose of study drug • Known history of human immunodeficiency virus (HIV) infection • Chronic or active hepatitis B or C, requiring antiviral therapy • Evidence of history of bleeding disorder, dialysis, or coexisting cancer that is distinct in primary site or histology from the cancer evaluated in this study • Serious, uncontrolled infection • Unresolved chronic toxicity > grade 1 from prior therapy • Use of strong CYP3A4 inhibitors or strong inducers within 7 days prior to the start of study treatment and for the duration of the study

The study cohort will be divided evenly into four groups, three receiving various doses of active drug and one receiving placebo.

Unlike clinical trials that compare an active drug to placebo pills, studies like these can't prove that alcohol has a direct effect on long - term health.

In the study, researchers identified 634 hematologist - oncologists who were active on Twitter and looked up whether they received personal payments from drug companies, unrelated to research or grants, in 2014.

In 86 % of cases, the study found, the amount of active ingredient present in the drugs was at least 90 % of the amount indicated on the label.

Treatment uses active chemical components of the The study by women's campaign group Platform 51 found that 48 per cent of women currently using the drugs have taken them for at least five years.

Studies done over the years have come to the conclusion that children who have an active father in their lives are less likely to drop out of school or be involved in crime and drug abuse.

This study (NIDA #R01DA025616) is a randomized clinical trial (RCT) that will compare an experimental treatment (OutPatient Treatment for Adolescents) to an «active placebo» on key indices (drug use; mental health; behavioral, school, peer, and family functioning; and consumer satisfaction) from pre-treatment through 18 months in order to evaluate its efficacy for youth referred to outpatient treatment of co-occurring substance use and internalizing problems.

Leonardson (1991), in evaluating a three - school Active Parenting of Teens pilot study for the Northeastern Drug and Alcohol Prevention Center in South Dakota, reported significant improvement in parent knowledge about effective methods of parenting and information about alcohol and other drugs as compared to a control group.