«This is the first indication that DISC1 regulates
the activity of a large number of genes, many of which are related to synapses,» Ming says.
Ikaros's function is to bind DNA and regulate
the activity of a large number of genes in cells.
Not exact matches
«Our new data is scientifically important because ataluren restores
activity to
genes inactivated by nonsense mutations, and as a result, it has the potential to do so much for a
large number of very complex genetic disorders,» Jacobson said.
«When we compared the
gene signature
activity of glioblastoma cells from around 60 patients we found that a
large number of patients could be divided into subgroups that showed a correlation between
gene activity, tumor cell characteristics and cell
of origin similar to the one we had seen in the mouse study.