Sentences with phrase «activity of genes linked»

At the core of this cell behavior is how the loss of that single gene changes activation levels of dozens of other genes, suppressing genes associated with metastatic disease and increasing activity of genes linked to normal tissue.

Not exact matches

The researchers found: cord plasma increased the activity of several genes linked to neural plasticity and memory; young adult plasma activated a subset of the same genes; and older adult plasma had no effect on gene expression.

This work is part of the ongoing Duke Neurogenetics Study (DNS), a comprehensive study linking genes, brain activity and other biological markers to risk for mental illness in young adults.

The team also recently obtained a grant from the National Medical Research Council in Singapore to pursue a study using the probe to examine the relationship between key Parkinson's disease - linked genes and MAO - B expression and activity to further understand the causes of the disease and illuminate the role of MAO - B in this.

More activity of the neuroligin - 3 gene in high - grade gliomas was linked to shorter survival among patients with these tumors.

The initial results published last year showed that people who scored in the top 15 percent of the U.C.L.A. Loneliness Scale, a self - administered psychiatric questionnaire for measuring the emotion, exhibited increased gene activity linked to inflammation and reduced gene activity associated with antibody production and antiviral responses.

Then, they added estrogen to see if gene activity changed, honing in on TLR8, an X chromosome - linked gene whose expression has already been implicated in the development of lupus.

Stice's group also genotyped these young women to determine whether or not they possessed variant alleles of two genes (DRD2 Taq1A A1 and DRD4 - 7 +) that have been linked with lower dopamine activity and, in some studies, obesity.

«These findings are extremely important,» says political scientist James Fowler at the University of California, San Diego, who has been doing research linking certain gene variations to political activity.

They found a link between MYC overexpression and the activity of spliceosome - related genes.

Varun Warrier added: «We now need to confirm these results using new genetic and brain scan data so as to understand how exactly gene activity and thickness of the cortex are linked in autism.»

The researchers now intend to investigate how the different processes that regulate DNA modifications and gene activity might be linked, and which regions of the genome are initially resistant to reprogramming and why that might be.

On the negative side, the researchers found that many of the genes whose activity is unique to modern humans are linked to diseases like Alzheimer's disease, autism and schizophrenia, suggesting that these recent changes in our brain may underlie some of the psychiatric disorders that are so common in humans today.

Genetic analysis also revealed significant increase in activity in two genes that may be involved in mitochondria function, suggesting that osteoclast activation might be linked to the reaction of mitochondria to microgravity.

The study *, published in the British Journal of Cancer ** today (Wednesday), showed a potential link between the activity of a gene called BCAR4 and the likelihood that a breast cancer tumour will not respond to tamoxifen — widely used to treat women with breast cancer.

They found that the absence of the RASGRF - 2 gene was linked to a significant reduction in alcohol - seeking activity.

Using an array of techniques, including RNA sequencing and targeted gene expression profiling, the researchers searched for links between gene activity and protein production in these tumors and the clinical outcomes of patients.

This was found to be linked to increased activity of a previously unstudied gene named betatrophin in liver and fat tissue.

Therefore, in some cases the process of inserting the healthy gene can increase the activity of cancer - linked genes, leading to tumour formation.

The gene variant produced a telltale pattern of activity linked to production of a key brain messenger chemical.

Genetic variation in HDAC4 among the women was linked to a lower level of HDAC4 gene activity and differences in their ability to respond to and recover from fear, and also differences in «resting state» brain imaging.