In the past year, biologists have been using the natural form of GFP to track the production of individual proteins or
the activity of particular genes in living cells.
In many cases,
the activity of particular genes was tied to a single genetic variant, with strong differences in frequency between European and African populations.
In June, he and his colleague Thaddeus Stappenbeck argued in Nature that all mouse studies should use littermate controls: When studying
the activity of a particular gene, breed mice with and without that gene by starting with heterozygous parents.
Not exact matches
Epigenetics (literally «above the
gene») is a recent scientific development that examines how
particular mechanisms can influence whether certain
genes are turned off, turned on, or modify a
gene's level
of activity.
The team found that humans are equipped with tiny differences in a
particular regulator
of gene activity, dubbed HARE5, that when introduced into a mouse embryo, led to a 12 % bigger brain than in the embryos treated with the HARE5 sequence from chimpanzees.
When produced in excess during times
of adversity, these
particular miRNAs trigger epigenetic changes, which alter
gene activity to cope with these environmental hardships.
It is now widely accepted among weight researchers that a person's
particular complement
of genes determines what
activities make him or her susceptible to weight gain as well as how strong that susceptibility is.
For example, some people have a
particular variant
of the ADH1B
gene that causes an amino acid change in this enzyme, which leads to faster enzyme
activity so individuals with this variant metabolize alcohol more rapidly which means that acetaldehyde levels are temporarily increased.
They sent soil samples for DNA testing, looking for matches with
particular genes known to be found in microbes and fungi; they tried to stimulate microbial growth on a wide variety
of substances and then count the cells produced; and they used highly sensitive radiorespiration
activity assays, which involve feeding the soil microorganisms a food source which has been labelled with radioactive carbon, which can then be used to detect if the microorganisms are active.
In research published this week in the Journal
of Neuroscience, University at Buffalo scientists and colleagues focused on a
particular protein, called a transcription factor, that regulates
gene activity necessary for the development
of one type
of retinal neuron, the horizontal cells.