When the researchers mimicked the process outside of a live animal, moreover, they verified the hormonal
activity of the osteocalcin that was released.
Not exact matches
Kandel showed — through a series
of tests in mice — that it was almost certainly
osteocalcin, which is secreted by cells in the bone, that regulated the gene's
activity.
It is unclear whether the absolute amount
of undercarboxylated
osteocalcin or its ratio to total
osteocalcin would be the best measure
of its hormonal
activity because no one to my knowledge has determined whether the carboxylated form interferes with the hormonal
activity of the undercarboxylated form.
Vitamin K2 activates the calcium - binding
activity of two proteins called Matrix gla protein and
osteocalcin, which help to build and maintain bones (13, 14).