For the first time, scientists have shown that a genetic element on one chromosome may direct gene
activity on another chromosome.
Not exact matches
In the illustration, each tissue type is followed by the number of genes whose level of
activity is controlled by nearby genes
on the same
chromosome (cis); those whose
activity is associated with genes
on other
chromosomes (trans); and the number of tissue samples studied.
Then, they added estrogen to see if gene
activity changed, honing in
on TLR8, an X
chromosome - linked gene whose expression has already been implicated in the development of lupus.
Reducing sedentary
activity appears to lengthen telomeres, which sit
on the end of
chromosomes, the DNA storage units in each cell, the findings show.
Genes that are grouped together
on chromosomes in other animals were dispersed in the octopus genome, likely as a result of transposon
activity.
In a paper published by Scientific Reports today, the research team found the
activity of this protein, called PTEN (for Phosphatase and tensin homolog deleted
on chromosome 10), is different between men and women.
Which parent a
chromosome comes from is important because the
activity of some genes varies depending
on whether the genes are
on a
chromosome inherited from the mother or from the father.
Their
activity outside the
chromosomes has been poorly studied; most research has focused
on phages integrated into bacterial
chromosomes.
The study, publishing online January 18 in the American Journal of Epidemiology, found elderly women with less than 40 minutes of moderate - to - vigorous physical
activity per day and who remain sedentary for more than 10 hours per day have shorter telomeres — tiny caps found
on the ends of DNA strands, like the plastic tips of shoelaces, that protect
chromosomes from deterioration and progressively shorten with age.
In
Activity 1, students identify the locations
on chromosomes of genes involved in cancer, using a set of 139 «Cancer Gene Cards» and associated posters.
Adults who had been categorized as behaviorally inhibited at the age of 2 years exhibited a higher amygdala activation in response to unknown vs familiar faces16 compared with adults who were uninhibited as children, consistent with the notion that novel or ambiguous environmental stimuli of potential biological relevance activate the amygdala.17 Turning to genes that can influence the neurobiological bases of the processing of emotions, 2 common alleles, the short (S) and the long (L), in a variable repeat sequence of the serotonin transporter (5 - HTT) promoter polymorphism (5 - HTTLPR)
on human
chromosome 17q11 have been differently associated with greater amygdala
activity in response to angry or fearful faces18 in healthy adults.