Its drug development expertise is being applied primarily to the fields of pain management, central nervous system disorders,
acute organ injury and metabolic diseases such as nonalcoholic fatty liver disease / nonalcoholic steatohepatitis.
Not exact matches
The new findings suggest that manipulation of NAD could lead to a future therapy for
acute kidney
injury and also raise the possibility that mitochondrial
injury and deficiency in NAD might underlie other types of
organ damage, including damage that can lead to stroke or heart attack.
As a result, Hausenloy said the results suggest the procedure may still be beneficial in other medical settings of
acute ischemia / reperfusion
injury, such as when treating heart attack patients or in
organ transplantation.
The HARP study showed that 80 mg of simvastatin administered acutely to patients with
acute lung
injury showed significant improvements in
organ failure scores, suggesting that statins modulate the systemic inflammation after only a short duration of treatment [17].