Oral
acute toxicity studies in rats indicated an LD50 greater than 4,640 mg / kg.
Acute toxicity studies showed no oral toxicity of J147 in mice at the maximum testable dose of 2 gm / kg and other safety tests including hERG, CYP450 inhibition and Ames were also negative which further supports the safety of J147.
Not exact matches
The author of the
study, T. Glinsukon, concluded that the
acute toxicity of capsaicinoids as a food additive in mankind was negligible.
The author of the
study, T. Glinsukon, concluded that the
acute toxicity of capsaicinoids as a food additive in mankind was neglible.
In other research published in the Journal of Hazardous Materials («Investigation of
acute effects of graphene oxide on wastewater microbial community: A case
study»), investigators determined that the
toxicity of GO was dose dependent and was toxic in the range of 50 to 300 mg / L.
Acute and subacute
toxicity study of 1,8 - cineole in mice Antimicrobial activity of essential oils and other plant extracts In Vitro Antibacterial Activity of Essential Oils against Streptococcus pyogenes In vitro antibacterial activity of some plant essential oils A near fatal case of high dose peppermint oil ingestion - Lessons learnt National Association for Holistic Aromatherapy Data Safety Sheet for Essential Oils during pregnancy International Association of Professional Aromatherapists Pregnancy Data Sheet (PDF) Robert Tisserand
Further testing is being pursued After passing chronic and
acute toxicity testing in animals, a pilot
study was undertaken with HCV patients.
Argentyn 23 also recently completed a murine
Acute Oral
Toxicity Study (LD50) with Covance Laboratories, Inc., (ref: 24742 -0-800).