Sentences with phrase «adaptive immunity against»
Clustered regularly interspaced short palindromic repeats (CRISPR) / CRISPR - associated (Cas) systems provide bacteria and archaea with adaptive immunity against viruses and plasmids by using CRISPR RNAs (crRNAs) to guide the silencing of invading nucleic acids.
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«Single dose Ebola vaccine is safe, effective in monkeys against outbreak strain: VSV - EBOV appears to trigger innate, adaptive immunity.»
As with innate immunity, the adaptive immune system — the T cells and antibodies produced by B cells that target specific molecules on invading cells — contributes to pathology or may also fight against it.
In 2007, Rodolphe Barrangou, a former Chairman of the Board of Directors of Caribou Biosciences and current scientific advisor, led the group that characterized CRISPR systems as a form of prokaryotic adaptive immunity that provides a critical line of defense against invading phages, plasmids, and environmental nucleic acids.
Dr. Barrangou and colleagues at DuPont established the biological role of CRISPR - Cas systems in adaptive immunity in bacteria, and used CRISPR - based technologies for bacterial genotyping of industrial cultures, and for the vaccination of dairy cultures against bacteriophages.