Sentences with phrase «adaptor protein»
An adaptor protein is a substance that helps in connecting different proteins together, like a bridge. It allows these proteins to interact and work together, enabling different cellular processes to happen efficiently. Full definition
Endocytosis of Frizzled 4 (Fz4) in human embryonic kidney 293 cells was dependent on added Wnt5A protein and was accomplished by the multifunctional adaptor protein β - arrestin 2 (βarr2), which was recruited to Fz4 by binding to phosphorylated Dvl2.
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The protein TRAF6 is a very important adaptor protein that is involved in multiple signaling pathways and its functions are important to maintain the stemness of satellite cells in adults,» Kumar said.
When the signal WOX5 enters the stem cells through pores, it binds at specific DNA sequences, the promoters, of target genes and recruits an enzyme via a so - called adaptor protein.
To initiate endocytosis, adaptor proteins need to recognize specific areas of the membrane to be internalized.
Matsuda and his team found that signal - transducing adaptor protein - 2 (STAP - 2) stabilizes EGFR by inhibiting its c - CBL - mediated ubiquitination.
TLR signaling requires TRIF and MyD88, two critical adaptor proteins for transmitting signals.
The majority of proteins found were identified as adaptor proteins, which serve as scaffolds within the Adherens Junction.
The research, published today in the Journal of Clinical Investigation, describes the role of TNF receptor - associated factor 6 (TRAF6), an adaptor protein and E3 ubiquitin ligase, in ensuring the vitality of stem cells that regenerate muscle tissue.
Using state - of - the - art techniques, researchers of VIB, Ghent University and the Max - Planck - Institute in Potsdam - Golm have now identified an adaptor protein complex which is essential for endocytosis and which only exists in plants.
Cardif is an adaptor protein in the RIG - I antiviral pathway and is targeted by hepatitis C virus.
A protein domain that is found in certain initiator caspases (for example, mammalian caspase - 9) and their adaptor proteins (for example, apoptotic - protease - activating factor 1, APAF1).
Interestingly, the binding site for NSF on the GluA2 C - terminus has been shown to overlap with that for AP - 2, an adaptor protein that is part of the clathrin - coated internalisation mechanism (Lee et al 2002).