Sentences with phrase «additional cell lines»

Both reviewers consider that since the functional studies were only tested in 2 basal and 2 luminal breast cancer cell lines, the sample set was too small, and testing additional cell lines for their dependency on MELK should further strengthen the authors conclusions.

The same pattern was seen in an extended panel of 6 additional cell lines representing the same subtypes of breast cancer (Supplementary Fig.

The 78 stem cell lines in existence would qualify for government - financed research, he said, but no additional money would be provided for additional cell lines.

Not exact matches

Entrepreneurs can often find money and additional profits by simply putting out for bid line items such as commercial loans, cell phone contracts and insurance premiums.

Memphis Meats acknowledges it used FBS to start its cell lines but says, «We have validated a production method that does not require the use of any serum, and we are developing additional methods as we speak.»

Collections include CIRM which is the California Institute for Regenerative Medicine, cell lined developed at Cellular Dynamics, and additional sources which will be added in a continuing basis.

While a monthly option is hosted, members are encouraged to use the on - line platform to create small cell groups for additional interest and geographic activities.

In yesterday's order, Lamberth wrote that they did not: «The prior [Bush Administration] guidelines, of course, allowed research only on existing stem cell lines, foreclosing additional destruction of embryos.»

Professor Ali Tavassoli, who led the study with colleague Dr. Ishna Mistry, explains: «In an effort to better understand the role of HIF - 1 in cancer, and to demonstrate the potential for inhibiting this protein in cancer therapy, we engineered a human cell line with an additional genetic circuit that produces the HIF - 1 inhibiting molecule when placed in a hypoxic environment.

The causes of such unpredictable results, Harris said, can include bad ingredients in the lab, including contaminated and misidentified cell lines; poor research design, including insufficient numbers of mice in animal studies; statistical error and overreach, including «HARKing» (hypothesizing after the results are known), a push beyond the limits of the data; and funding pressures, which can lead scientists to hype or exaggerate their results to remain competitive for additional grant money.

Much of the money went into infrastructure that will enable the creation of additional clinical - grade cell lines, he says.

We also examined several of the cell lines for the presence of additional receptors that are generally considered characteristic of the microvascular phenotype.

Indeed, we found that in cell lines maintained at the nonpermissive temperature (37 °C) for two to three additional passages, cells began to assume characteristics associated with a senescent phenotype (formation of giant cells, absence of cell division).

During the next five years, KOMP2 will transform the knockout mouse embryonic stem (ES) cells into adult mice for 2,500 lines of well - characterized knockout mice strains, and IMPC will create about 2,500 additional knockout mouse strains.

When President Bush became the first president ever to fund embryonic stem - cell research, he set a clear moral line: the government would not be complicit in encouraging additional embryo destruction.

We then isolated and exposed this novel subpopulation to additional cycles of hypoxia / reoxygenation and established a distinct subpopulation of cells from these two breast cancer cell lines.

Since then, additional hESC lines have been created (a «line» consists of all the cells grown from one given blastocyst).

The technical evaluation of projects may require the provision of additional data such as information on the genetic modification of your mutant mouse line if applicable (e.g. affected gene, MGI ID of the gene, type of mutation, ES - cell line used, genetic background (e.g. number of backcross generations), safety level, description of DNA modification, vector, remaining non-recipient DNA, donor organism), mutant phenotype (s), special housing or care requirements, current sanitary status, and intellectual property rights (who generated the mouse line, owner of the mouse line)

See Requesting MMRRC Strains and Cell Lines for additional information.

As an additional control we also tested the effect of amiodarone HCl on an immortal cell line 2102Ep cells [13].

The MMRRC currently holds 24 mouse models and several ES cell lines from this collection and the MMRRC at UC Davis will generate an additional group of mouse models for this collection from the supplied ES cells.