Sentences with phrase «additional cell types»

Cembrowski also wants to extend this work across the full extent of the subiculum to see if they can identify additional cell types.

Marcus stresses that SaGA can be applied to additional cell types or environments, or other types of cancer cell behavior such as drug resistance.

Not exact matches

Not that a principled moral objection shouldn't be enough, but, for those sitting on the fence, the additional discoveries of alternative sources of embryonic - type stem cells should be decisive.

Some cells of this type have additional protection at the cable entry such as a glass - to - metal seal.

Setton says the multistep process her lab used to derive NP - type cells from the hiPSCs provides the necessary quality control as scientists seek additional uses for stem cell therapies.

Additional experiments revealed that a class of immune cells, T helper type 2 (Th2) cells, that many consider critical to triggering asthma prompted levels of the chitinase enzyme to soar.

Raquel Oliveira, first author of this study, explains: «Many cancer cells have these type of chromosomal abnormalities and we now show that this can bring additional problems every time a cell divides.»

In an experimental setup that allowed the two types of cells to bathe in the same fluid without coming into physical contact, retinal neurons in a bath with hUTCs formed new connections between neurons called synapses, and they sprouted new «neurites» — tiny branches that lead to additional connections.

Specifically, they found that chemotherapy alone leads to two types of dormant cancer cells that are not killed outright and become resistant to additional chemotherapy, but when combined with immunotherapy, a majority of dormant cells also is destroyed.

He noted that before physicians and scientists begin offering SSC transplantation in patients, additional research will be needed, including whether other types of leukemia cells will also be eliminated in the cell - propagation process.

EPFL scientists have now discovered an additional component: chronic inflammation can cause cells to actually change type — here, eye cells turned into skin.

But additional research presented at the meeting may boost their efficiency: teams from Tokyo University of Science and Notre Dame both revealed new types of dyes that could extend the spectrum of light captured by such cells into the infrared range.

Study authors then further refined the process, identifying additional molecular signaling pathways that drive formation of critical stomach cell types of the fundus.

This causes the body's white blood cells to release type 1 interferon - alpha, a small cytokine protein that acts as a systemic alarm, triggering a cascade of additional immune activity as it binds with receptors in different tissues.

Unlike atomic force microscopy, microfluidics is a high - throughput screening technique, but additional work is required to assess the efficiency of this type of biophysical - based sorting for stem cell enrichment.

Additional CD4 + T cell types have been discovered, including those producing IL - 17 (Th17 cells), that likely participate in the induction of IBD.

While CRISPR / Cas9 is a powerful technique for genome manipulation, two significant challenges remain: obtaining efficient delivery of the Cas9 / sgRNA complex to all cell types, and leaving no additional footprint (i.e., persistent and elevated expression of Cas9 in target cells) that could lead to off - target effects.

The technical evaluation of projects may require the provision of additional data such as information on the genetic modification of your mutant mouse line if applicable (e.g. affected gene, MGI ID of the gene, type of mutation, ES - cell line used, genetic background (e.g. number of backcross generations), safety level, description of DNA modification, vector, remaining non-recipient DNA, donor organism), mutant phenotype (s), special housing or care requirements, current sanitary status, and intellectual property rights (who generated the mouse line, owner of the mouse line)

Recently, Rothman and Südhof described the role of the Rab proteins and the SM (Sec1 / Munc18 - like) proteins in providing additional specificity and control to the process of SNARE scaffold assembly and vesicle docking to membranes in various cell types, thus confirming the general importance of these proteins (Science, vol 323, 23 January 2009).

Partial clinical hold on high dose SGT - 001 resolved, additional information requested on full clinical hold NIH grant will further development of replacement beta cells for type 1 and type 2 diabetes New trial will assess MSCs to improve heart function in heart failure patients ReNeuron wins grant for retinal cell therapy development

The discovery of EPAC as an additional intracellular cAMP receptor [29], the finding that cAMP - induced PKA (but not EPAC) signaling is coupled to the p38 MAPK pathway in some cell types [30], and the observation that SB202190 partially, but not completely, inhibited 8 - Br - cAMP - stimulated Oct4 activity (Figure 4D) led us to ask whether all of the 8 - Br - cAMP response was mediated through PKA / p38 MAPK.

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Additional processing, such as softening bones so they can be sectioned easily, or applying special stains or markers to identify specific types of cells, are occasionally needed.