If Rudenko confirms Clark's PCR tests using
additional gene targets, and if Clark or Rudenko manage to grow Borrelia cultures out of human and lone star tick samples, then even the fiercest skeptics will have to recognize that Southern Lyme strains threaten human health, and that Lyme - like illness deserves Lyme - like treatment.
Not exact matches
Our data demonstrate the feasibility of
targeted gene disruption in multiple rat strains within 4 months time, paving the way to a humanized monoclonal antibody platform and
additional human disease models.
Although the study doesn't point to immediate treatment possibilities, Heitman says that many researchers are studying the mechanisms that allow cells to tolerate the many extra proteins produced by the
additional genes, which might reveal a weakness to
target.
Additional genes included in the database could be the focus of future drug development efforts because they belong to classes of
genes that are thought to make promising drug
targets.
GOMiner — To provide
additional statistical stringency to the identification of potential
targets, we then analyzed the data sets generated by the SAM - RS analysis of the microarray data for hypoxia - associated coregulation of multiple, functionally related
genes.
It may provide an exciting
additional target for further
gene and drug discovery.
This effort, which will enhance deCODE's proprietary
gene and drug
target discovery work and may provide genetic markers for
additional diagnostic development, will leverage Illumina's Sentrix ® HumanHap BeadChips; Infinium ™ assay and LIMS (laboratory information management system); as well as analysis and visualization tools from Illumina's BeadStudio software.
This
gene finding may allow scientists to identify patients with this aggressive form of the cancer and
target them with
additional therapies.
These laboratories are complemented by several
additional laboratories: one that is focused on computational structure prediction and design (Phil Bradley), one that conducts solution - based protein mapping studies of large complexes involved in
gene transcription (Steve Hahn) and a third that conducts drug
target validation and drug screening studies (Julian Simon).
Additional predicted
gene targets were verified to bind Oct4 in situ, and
targets were found to be enriched in several developmental and molecular processes by
gene ontology analysis.
This research includes identifying
additional genes associated with disease incidence in order to identify potential drug
targets.
Unlike the fluid mix of crew and actors - namely American headliners Richard Widmark and
Gene Tierney, plus a fine supporting British cast - the film's music soundtracks and longer /
additional scenes in the British version reflect their
target cultures.