Sentences with phrase «additional mutations not»
In some breeds, such as the French Bulldog, additional mutations not identified may affect eumelanin production.
http://www.animalgenetics.us/ Not exact matches
The authors conclude by raising what they consider to be «a broader ethical problem with OAR,» stating that this procedure amounts to nothing more than human cloning with the additional twist of introducing a genetic mutation» ominously concluding that a «combination of wrongs can not make the end result good.»
The TERT promoter mutation does not generate enough telomerase to immortalize the pre-cancerous cells, but does delay normal cellular aging, Hockemeyer said, allowing more time for additional changes that turns telomerase up.
However, not all dogs with the mutation became affected, prompting the hypothesis that additional genes could modify disease risk.
Velculescu cautions that medical practice may not change much until additional studies validate their findings, and there are ongoing clinical trials studying the removal of fallopian tubes instead of ovaries in women with cancer - causing, hereditary BRCA1 and BRCA2 mutations.
In some patients, the cancer cells carrying the T790 - M mutation acquired an additional EGFR mutation not seen before, labeled C797S, which blocked the AZD9291 from docking to the tumor cells, and causing the disease to advance.
Additional investigation showed that the mutations that squelched steroid family members» ability to bind DNA repressively didn't affect the part of the protein that directly contacts the DNA.
And researchers can not yet easily distinguish between mutations that are driving the cancer process versus those that are essentially artifacts of that process, without doing additional experiments once they have been identified.
«That's why a lot of East Asians can't metabolize alcohol,» Pritchard said, «but mutations in this pathway must have some additional positive effect that has been favored by natural selection.»
Given the possibility that there may be additional JAK2 mutations in AML, we resequenced all coding exons of JAK2 in 93 AML samples and did not identify additional JAK2 mutations.
WEDNESDAY, April 12, 2017 (HealthDay News)-- Close to half of breast cancer patients who chose to have a double mastectomy after genetic testing didn't actually have the gene mutations known to raise the risk of additional cancers, a new survey found.