Sentences with word «adduct»

The DNA adducts in her study weren't linked with the other two factors that she measured.

Ellagic acid inhibits mutagenesis and carcinogenesis by forming adducts with DNA, thus masking binding sites to be occupied by the mutagen or carcinogen (Teel).

CDDO - Me reacted with thiol groups as determined by detection of specific adducts by LC - MS (Tables S1 and S2 and Figure S3 in Data S2).

A simple standing twist with a chair and Ardha Matsyendrasana (Half Lord of the Fishes Pose) would be good options for stretching it since they place your leg into flexed / adducted position without the external rotation element, which is milder for piriformis.

I would have this individual stand up, straighten out their arm, internally rotate their shoulder and bring it across the body (horizontally adduct with internal rotation) and press it against an immovable object for about 5 to 10 seconds at about 50 % effort.

Modern human footprints reflect the specialized anatomy and function of the human foot, which is characterized by a fully adducted hallux [big toe in line with the other toes], a large and robust calcaneus [heel] and tarsal region, a pronounced medial longitudinal arch, and short toes.

This repair process, which also occurs in animal cells, fixes one of the most common forms of DNA damage: the bulky adduct, an unwanted chemical modification of DNA typically caused by a toxin or ultraviolet (UV) radiation.

Researchers examined formation of DNA - damaging adducts in liver cells treated with omega 6.

Although the metatarsal robusticity sequence is human - like and the hallux is fully adducted, other intrinsic proportions and pedal features are more ape - like.

Proteins are modified by glycation, oxidation and nitration leading to formation of glycation, oxidation and nitration adducts residues in proteins — including formation of non-disulfide crosslinks.

Damaged proteins undergo proteolysis to form glycated, oxidised and nitrated amino acids or free adducts that are then metabolised or excreted.

As expected, the mutational spectrum was enriched for G - > T and C - > A changes associated with adduct formation on guanine nucleotides induced by benzopyrene, the chemical mutagen found in tobacco smoke.

The pectoralis major muscle adducts your bone, which is basically drawing the arm to the middle of the body.

Moreover, we have developed mass spectrometric methods for measuring protein adducts of the levuglandins, and find that they are increased by 12 fold in the brains of patients who died of Alzheimer's disease.

Characterization of a cyanide — carbon dioxide adduct bolsters its possible role in protecting a plant enzyme from cyanide inhibition.

Even with the big toe adducted into line with the others, the long lateral toes give a hint of the hand - like look of the feet of nonhuman primates.

Here, the researchers discovered that RAPTA - T helps the other drug's ability to form histone adducts by binding on distant histone sites.

Here, we report hominin footprints in two sedimentary layers dated at 1.51 to 1.53 million years ago (Ma) at Ileret, Kenya, providing the oldest evidence of an essentially modern human — like foot anatomy, with a relatively adducted hallux, medial longitudinal arch, and medial weight transfer before push - off.

One of the JACS papers reported growing a polymer from a [4 + 2] cycloaddition adduct using an initiator originating from David Haddleton's University of Warwick team.

Perera and Weinstein detected the benzo [a] pyrene adduct in some of the cancer patients but not in the control group.

The third antioxidant tested, alpha - lipoic acid — found in spinach and broccoli and proven to have anti-cancer properties — had no effect on either of the two adducts studied.

«My group in 1979 showed the molecular structure of the B [a] P adduct.

If the compound is reactive, a thiol - containing adduct will be formed that is detectable using mass spectrometry.

(D) Protein carbonyls were detected at different concentrations (2.5, 5, 10 pM) as (DNP) hydrazone adducts via immunoblots with a DNP antibody.

It should not require a dozen silly movements like those planks where you extend your left arm and right leg and repeat, or squats to overhead presses with dumbbells, or walking lunges while wiggling your wrists and attempting to forcefully adduct your big toe.

4 - OH estrone (4 - OH E1): An estrone metabolite that can be enzymatically oxidized to catechol estrogen quinones, which can damage DNA by forming predominantly depurinating adducts.

In this variation, the upper leg crosses all the way over, thus adducting the femur and stretching the muscle.

Don't want to be coming at you all technical and stuff, but if someone stands with their feet more adducted then all the «changes» seen here can be replicated.

The pectoralis major horizontally adducts the shoulder.

Here's why: When the DNA of a bacterial gene is being transcribed into RNA, and the molecular machinery of transcription gets stuck at a bulky adduct, Mfd appears on the scene, recruits other repair proteins that snip away the damaged section of DNA, and «un-sticks» the transcription machinery so that it can resume its work.

This muscle adducts, extends, and medially rotates the arm.

E2 can be activated by epoxide - forming oxidants resulting in the ability to bind to DNA and form DNA adducts, which can cause mutation leading to carcinogenesis.

In contrast, auranofin is much less prone to form adducts with the histone proteins, unless the two drugs are used together.

To study excision repair in cells, Sancar, Selby and colleagues recently developed a new technique, XR - seq, which allows investigators to isolate and sequence the small lengths of adduct - damaged DNA that are snipped from the genome during the excision repair process.

These adducts may also change the functions of genes that promote or suppress disease, although exactly how they might lead to developmental decrements in fetuses exposed to them is unclear.

The findings in China confirm earlier research indicating that PAH - DNA adducts can serve as a fingerprint of exposure to pollution.

These adducts disrupt the normal function of DNA and cause the cell to die.

When RAPTA - T is given, it forms what are known as «adducts» with the histone proteins that package DNA.

To elucidate the nature of the water adduct of PaO2 +, hydration of PaO2 + and UO2 +, as well as collision - induced dissociation and ligand - exchange of the water adducts of PaO2 + and UO2 +, were studied in an ion trap.

Blood levels of lead predict neurological deficits far better than any DNA adduct or aberrations can predict a cancer.

Individuals differ greatly in the amounts of adducts that their blood and tissues will express in response to an exposure: The range can be 100-fold or more.

«Contrary to our hypothesis,» she replies cheerfully, «the exposures correlated stronger [to the chromosomal aberrations] than the adducts did.

The vitamin promoted the formation of an «adduct,» a structure that links a chemical to DNA, and which may cause mutations.

According to other research, both classes of markers — the adducts and the chromosomal aberrations — are associated with increased risks of all cancers.

One is a type of molecule, called an adduct, in which a hydrocarbon locks onto a part of the DNA.