The research, published in the current issue of the journal Science, demonstrates that brain cells, known as astrocytes, which play fundamental roles in nearly all aspects of brain function, can be
adjusted by neurons in response to injury and disease.
Not exact matches
By adjusting the opening or closing of channels in cell membranes, opsins can switch
neurons on or turn them off.
In the new study, the team focused on
neurons called amacrine cells and horizontal cells, which have a known role in «preprocessing» — or
adjusting — electrical signals transmitted to the brain from the photoreceptors after they have been stimulated
by light photons.
Published in
Neuron, scientists at Cold Spring Harbor Laboratory (CSHL) report their discovery of a neural circuit in the mouse olfactory bulb that explains how our mammalian cousins (and
by extension, we) are able to
adjust the gain on intense odors.
To cope, the
neurons used methylation and demethylation like a volume knob, constantly
adjusting the signal strength of connected
neurons by turning on or off the genes that make the signal receptors.