Sentences with phrase «adjuvant ipilimumab»
«Adjuvant Ipilimumab effects survival after high risk lymph node and melanoma resection.»
https://www.sciencedaily.com/ Not exact matches
Indeed, the authors point out that Ipilimumab might better effect recurrence - free survival than adjuvant interferon and should be considered as an option by oncologists in this field considering its activity across subgroups including those with high tumor burden.
Ipilimumab as adjuvant therapy significantly improves overall survival in patients with high risk stage III melanoma, according to the EORTC 18071 phase III trial results presented for the first time at the ESMO 2016 Congress in Copenhagen.
«Ipilimumab as adjuvant therapy improves overall survival in high risk stage III melanoma.»
The EORTC 18071 phase III trial evaluated ipilimumab as adjuvant therapy for patients with high risk stage III melanoma.
As reported in 2015, the study met its primary endpoint after a median follow up of 2.3 years, with ipilimumab significantly improving recurrence - free survival.2 The drug was subsequently approved by the US Food and Drug Administration as adjuvant therapy for stage III melanoma.
Our intention with this study was to assess Ipilimumab as an adjuvant treatment for patients with completely resected stage III melanoma at high risk of recurrence.
Currently, lymphadenectomy is an eligibility requirement for cutting - edge adjuvant therapy trials such as Southwest Oncology Group (SWOG) 1404 (ClinicalTrials.gov identifier: NCT02506153), which randomizes stage III melanoma patients to an anti — programmed death 1 antibody or standard - of - care adjuvant therapy (high - dose interferon or high - dose ipilimumab).
«They show for the first time that an anti — PD - 1 drug is superior in the adjuvant setting and because of its lower toxicity nivolumab is much easier to give than ipilimumab.»
As a single agent, ipilimumab is approved as a second - line treatment, as well as adjuvant therapy for patients with completely resected melanoma.
A recent study, she said, looked at adjuvant nivolumab vs ipilimumab in patients with resected stage III or IV melanoma.