Sentences with phrase «administration of adjuvant»

Conventional standard therapy for canine appendicular OSA includes amputation of the affected limb, and administration of adjuvant chemotherapy.

«In an era of increasing use of minimally invasive surgery that enables administration of adjuvant therapy more reliably,» says Dr. Yendamuri, «the paradigm of routine neoadjuvant therapy for patients with this stage of disease should be reconsidered.»

Not exact matches

As reported in 2015, the study met its primary endpoint after a median follow up of 2.3 years, with ipilimumab significantly improving recurrence - free survival.2 The drug was subsequently approved by the US Food and Drug Administration as adjuvant therapy for stage III melanoma.

Administration of this complex of pathogen and adjuvant via a mucosal surface (e.g. in the nose) serves to inform memory cells in lymph nodes about the nature and location of the supposed infection.

The HZI will develop a vaccination protocol for mucosal administration based on three novel strategies: (i) development and optimization of a vaccination protocol in which parenterally - primed T and B cells are subsequently pulled into the mucosa by the local delivery of the cognate antigen to the requested effector site, (ii) testing the co-administration of antigens with novel mucosal adjuvants using different mucosal immunisation routes and schedules, and (iii) testing various nanoparticles co-administered with different immunomodulators for their ability to generate both systemic and mucosal immune responses following transcutaneous / trans - follicular vaccination.

In the regulatory affairs arena, her group provides the necessary documentation to the U.S. Food and Drug Administration for review and approval of IDRI's vaccine and adjuvant candidates in human clinical trials.

Tater KC, Jackson HA, Paps J, Hammerberg B. Effects of routine prophylactic vaccination or administration of aluminum adjuvant alone on allergen - specific serum IgE and IgG responses in allergic dogs.