HDAC - induced chromatin remodeling appears to be very important in regulating the anxiety - like behavior that appears during alcohol withdrawal, or
the adolescent alcohol exposure - induced anxiety and drinking behavior at adulthood.
«Anxiety disorder is highly comorbid with alcoholism,» he said, «and
adolescent alcohol exposure can lead to the development of high anxiety and alcohol intake in adulthood.»
«More specifically, our data indicate that the enzymes histone deacetylases and demethylases — which are responsible for the regulation of histone acetylation and methylation — are altered in adulthood due to previous
adolescent alcohol exposure.
Not exact matches
Mice in booze camp In the new study, performed on
adolescent male mice, ethanol
alcohol exposure seemed to enhance synaptic plasticity in the ventral tegmental area (VTA), a part of the brain that plays a critical role in the reward pathway.
With repeated
exposure to the caffeinated
alcohol, those
adolescent mice became increasingly more active, much like mice given cocaine.
«Our results indicate that specific types of HDACs are altered by chronic
alcohol exposure; both in the adult brain and in the
adolescent brain.
Type 2 Neural Progenitor Cell Activation Drives Reactive Neurogenesis after Binge - Like
Alcohol Exposure in
Adolescent Male Rats
Specifically analyzes the connection between
adolescent risk factors and early
exposure to
alcohol, tobacco, and marijuana use.
Adolescents seek independence but can find themselves alone and struggling with peer relationships, pressures to succeed, and
exposure to drugs and
alcohol.
This study investigated associations of contextual variables of risk (stressful events and
exposure to community violence), variables of protection (family environment, connectivity to the school and community perceptions) and demographic variables (gender and age) with indicators of psychosocial adjustment (self - esteem, involvement in illegal activities and
alcohol use in past month) among
adolescents.