To highlight the potentially important role of 3D culture conditions, the authors compared 2D monolayers of hepatocyte progenitors, fetal liver stromal cells, or
adult bone marrow - derived stromal progenitor cells to their 3D counterparts cultured on liver extracellular matrix (3D - ECM) constructs.
Sphingosine -1-Phosphate Mediates Proliferation Maintaining the Multipotency of Human
Adult Bone Marrow and Adipose Tissue - derived Stem Cells (Retracted article.
Isolation and characterization of mesenchymal
adult bone marrow stem cells (MSC) and hematopoietic stem cells (HSC) from healthy donors and patients with leukemia.
Sphingosine -1-phosphate mediates proliferation maintaining the multipotency of human
adult bone marrow and adipose tissue - derived stem cells.
Sphingosine -1-phosphate mediates proliferation maintaining the multipotency of human
adult bone marrow and adipose tissue - derived stem cells (Retraction of vol 2, pg 199, 2010).
Telomerase activity in candidate stem cells from fetal liver and
adult bone marrow.
Additional data * of immune cells from umbilical cord blood and
adult bone marrow was provided by the Broad Institute of MIT and Harvard.
By the 1970s researchers had recognized another type of progenitor cell in
the adult bone marrow, which they named the mesenchymal stem cell.
Stem cells from
adult bone marrow normally generate bone, muscle, cartilage and fat cellsa limited set compared with embryonic stem cells, which can spawn the full spectrum of adult tissues.
She is one of 16 patients in the first U.S. trial using cells extracted from
adult bone marrow to reverse advanced heart failure.
They showed for the first time how three key molecules interact together to generate the cells, which are later found in
adult bone marrow.
Not exact matches
The company isolates, cultures and processes
adult stem cells from a patient's
bone marrow or synovial fluid.
Wagers was inspired to research
bone marrow stem cells and did her postdoctoral work on
adult stem cells.
This basic fact makes it difficult for researchers to discern the underlying mechanism of the disease: «It's very difficult to figure out what's wrong, because the
bone marrow is nearly empty of these cells,» said Bessler, the director of CHOP's Pediatric and Adult Comprehensive Bone Marrow Failure Cen
bone marrow is nearly empty of these cells,» said Bessler, the director of CHOP's Pediatric and Adult Comprehensive Bone Marrow Failure C
marrow is nearly empty of these cells,» said Bessler, the director of CHOP's Pediatric and
Adult Comprehensive
Bone Marrow Failure Cen
Bone Marrow Failure C
Marrow Failure Center.
They may arise from either embryonic progenitors or
bone marrow cells in
adults.
Hematopoietic stem cells —
bone marrow - derived
adult stem cells that give rise to the wide variety of specialized blood cells — come in two flavors: the reserve force sits quietly waiting to be called upon while the active arm continually proliferates spawning billions of blood cells every day.
The second group received chemotherapy along with
adult stem cells taken from their own
bone marrow.
The stem cells used to treat Paizley, specific to the blood, came from the
bone marrow of a healthy
adult donor.
• A Yale research team led by Diane Krause turned a single stem cell from the
bone marrow of an
adult mouse into lung, liver, intestinal, and skin cells for other mice.
HSCs are a type of
adult stem cell that live in little niches in the
bone marrow.
He adds, however, that if they work as reported, MAPCs are still not very efficient: one
adult blood - forming stem cell replaced as much
bone marrow as a million MAPCs.
Institute director Catherine Verfaille and her team pulled multipotent
adult progenitor cells, referred to as MAPCs (and pronounced map - seas), from the
bone marrow of mice and rats.
Adult stem cell treatments have been used for many years to treat successfully leukemia and related
bone / blood cancers through
bone marrow transplants.
The New York Yankees» Bartolo Colon has emerged as the exception this season after receiving injections of
adult stem cells taken from his own fat and
bone marrow.
«Umbilical cord blood contains an enriched population of
bone marrow stem cells,» says Daniel Weisdorf, director of the Adult Blood and Marrow Transplant Program at the unive
marrow stem cells,» says Daniel Weisdorf, director of the
Adult Blood and
Marrow Transplant Program at the unive
Marrow Transplant Program at the university.
The study enrolled 61 older
adults from the University of Michigan and Washington University in St. Louis who were undergoing a reduced - intensity
bone marrow transplant with cells donated from a relative.
Researchers at the Whitehead Institute in Cambridge, Massachusetts, US, have now found that
adult stem cells in
bone marrow gradually lose their ability to regenerate without their normal complement of membrane - bound prions.
Basel, Switzerland (Scicasts)-- Stable joint cartilage can be produced from
adult stem cells originating from
bone marrow.
Over the years, Dr. Nimer has conducted extensive clinical and basic science research into the treatment and genetic basis of
adult leukemia and
bone marrow failure states, defining the regulatory mechanisms that control the production of blood cells and exploring ways to improve the treatment of blood based cancers.
Comparison of human
adult stem cells from adipose tissue and
bone marrow in the treatment of experimental autoimmune encephalomyelitis.
Adult stem cells known as mesenchymal stem cells (MSCs) are repair cells that are found in many tissues of the body and have been studied for many years in
bone marrow.
(
Bone marrow transplants use
adult stem cells, a treatment that has been used for decades.)
A number of
adult stem cell therapies already exist, particularly
bone marrow transplants that are used to treat leukemia.
Near the time of birth, stem cells from the liver populate the
bone marrow, which then becomes the major site of blood formation throughout
adult life.
Differentiation, cell fusion, and nuclear fusion during ex vivo repair of epithelium by human
adult stem cells from
bone marrow stroma.
There are many different types of
adult stem cells: umbilical cord blood stem cells,
bone marrow stem cells, mesenchymal stem cells, endothelial stem cells, cardiac stem cells, muscle stem cells, and others.
It's a bit like a computer back up; by banking your stem cells, you have a «backup» to help restore the
bone marrow and a compromised immune system through
adult stem cell therapyif ever needed.
Adult stem / progenitor cells are present in many organs and tissues, e.g.,
bone marrow, teeth, heart, gut, kidney and liver, and remain quiescent for long period of time until activated by a disease or injury trigger.
The largest number of
adult stem cells is present in the umbilical cord blood and in
bone marrow and they have been used effectively for decades to treat cancers, blood and immune disorders.
The history of the first
bone marrow transplant Jovana Drinjakovic of the Signals blog wrote a wonderful story about the first
bone marrow transplant cases in
adults:
By studying how the rat body accepts or rejects transplanted pancreas, skin, heart, kidney, or
bone marrow, scientists have helped medical doctors successfully perform life - saving transplants in human
adults and children.
Researchers previously reported promising results in adolescents and young
adults with XSCID who were treated with the St. Jude vector and low - dose chemotherapy after
bone marrow transplantation failed to restore adequate immune protection.
Adult stem cells mainly reside in the
bone marrow.
Bone marrow also contains a second type of
adult stem cell known as a stromal or mesenchymal stem cell.
In contrast,
adult stem cells are derived from mature tissue, typically from
bone marrow, but increasingly from most organs.
In 2004 she transferred to the NIDCR and heads the
Adult Stem Cell Section to study the biology of
bone marrow derived stem cells.
Early and accurate diagnosis of
bone marrow failure or MDS allows optimal medical management and treatment to improve the health of children, adolescents, and young
adults with these disorders.
Certain mesenchymal stem / stromal cells from the
bone marrow of
adults are considered extremely promising for skeletal tissue regeneration.
Our initial studies were on characterization of different
adult neural stem cell types from murine and human brain and human
bone marrow.
The data set, one of the largest of its kind, includes primary data and associated metadata from nearly 530,000 immune cells from umbilical cord blood of newborns and
bone marrow of
adults.