He'd never been able to get an adult frog by using nuclear transfer from
an adult cell donor.
Not exact matches
In this process, the nucleus of a
donor adult cell is transferred to an egg whose nucleus, and thus its genetic material, has been removed.
Both involve a technique called nuclear transplantation — replacing the nucleus of a
donor's egg with the DNA from an
adult cell.
Research involving the derivation and use of stem
cells from
adult tissues is permissible, subject to the informed consent of the tissue
donor.
CLL is the most prevalent leukemia in
adults and it is not considered curable without an allogeneic (
donor) stem
cell transplant.
Scientists had suggested that it might one day be possible to circumvent the shortage of
donor eggs from
adult women by developing ways of maturing undeveloped egg
cells from a fetus in the laboratory (This Week, 15 January).
The stem
cells used to treat Paizley, specific to the blood, came from the bone marrow of a healthy
adult donor.
Abatacept, when added to the standard drug regimen used to prevent GvHD, reduced the occurrence of acute, grade III - IV GvHD from 32 to 3 percent in pediatric and
adult patients who underwent mismatched unrelated
donor stem
cell transplants to treat advanced cancer and other blood disorders.
But brain
cells that had been created using the direct conversion technique had different patterns of gene expression depending on whether they were created from young
donors or older
adults.
Prins took human prostate stem
cells from deceased young
adult male organ
donors and implanted the
cells into mice, where they formed human prostate tissue.
A key difference, however, is that Dolly's
donor cell came from
adult udder
cells growing in lab dishes (see ScienceNOW, 24 February), while the
donor cells used to create the monkey clones came from early embryos.
In later stages, the trial will deliver cord blood
cells from
donors to children and
adults with autism.
However, these problems associated with histocompatibility may be solved using autologous
donor adult stem
cells, therapeutic cloning, stem
cell banks or more recently by reprogramming of somatic
cells with defined factors (e.g. induced pluripotent stem
cells).
There is also a different type of stem
cell that can be found in
adults, and obtained without any harm or discomfort to the
donor.
Animal cloning uses a process known as somatic -
cell nuclear transfer, where the nucleus from an
adult (
donor)
cell is transferred into an egg (host)
cell lacking a nucleus.
Human epidermis has been produced in vitro for decades using
adult epidermal stem
cells from
donors to provide
cell therapy.
For the other
adult patients that might still benefit from a cord blood
donor, either two cord blood units are combined for a single transplant, or more recently, there are some exciting new graft engineering technologies that are emerging to expand stem or progenitor
cells in the laboratory before infusion or modify the
cells in some way to make them more potent at the time of transplant.
Isolation and characterization of mesenchymal
adult bone marrow stem
cells (MSC) and hematopoietic stem
cells (HSC) from healthy
donors and patients with leukemia.
Cymerus is a patented stem
cell manufacturing process that avoids the problems often associated with deriving MSCs and primary tissue sources, and has the potential to generate large - scale, low - cost MSCs based on a single blood donation from one
adult donor.
An
adult cell from the mammary gland of a Finn - Dorset ewe acted as the nuclear
donor; it was fused with an enucleated egg from a Scottish Blackface ewe, which acted as the cytoplasmic (or egg)
donor.