Sentences with phrase «adult epidermis»
Remarkably, the short - term presence of cells with supernumerary centrosomes in PLK4OE / p53cKO mice was sufficient to generate aneuploidy in the adult epidermis and triggered spontaneous skin cancers with complete penetrance.
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Scientists from the Spanish National Cancer Research Centre (CNIO) have discovered that NANOG, an essential gene for embryonic stem cells, also regulates cell division in stratified epithelia — those that form part of the epidermis of the skin or cover the esophagus or the vagina — in adult organisms.
Human epidermis has been produced in vitro for decades using adult epidermal stem cells from donors to provide cell therapy.