It involves isolation and propagation of
adult epithelial stem cells, prepared from tissue specimens at different early stages of chronic and atrophic gastritis, as well as from the late, premalignant (irreversible) stage of metaplasia.
Using Cultrex ® BME, MimEX ™ Tissue Models System provides a platform for the isolation, expansion, and differentiation of
adult epithelial stem cells into 3 - D ex vivo organ tissue.
MimEX ™ Tissue Models System provides a platform for the isolation, expansion, and differentiation of
adult epithelial stem cells into 3 - D ex vivo organ tissue.
First, the MimEX ™ Cell Plating Procedure is used to maintain a uniform irradiated fibroblast monolayer for the rapid clonal expansion and efficient differentiation of tissue - specific
adult epithelial stem cells.
This distribution helps to maintain the health and rapid proliferation rate of
adult epithelial stem cells using MimEX ™ Tissue Model Systems.
Not exact matches
Three years after publishing a groundbreaking paper in which she isolated
adult retinal pigment
epithelial stem cells, Temple is in preclinical trials with rats.
Xiaowei «George» Xu, MD, PhD, associate professor of Pathology and Laboratory Medicine and Dermatology at the Perelman School of Medicine, University of Pennsylvania, and colleagues published in Nature Communications a method for converting
adult cells into
epithelial stem cells (EpSCs), the first time anyone has achieved this in either humans or mice.
First, a hair follicle contains
epithelial cells — a
cell type that lines the body's vessels and cavities — as well as a specific kind of
adult stem cell called dermal papillae.
Initial reprogramming efforts used
adult mouse limbal progenitors (
epithelial cells which express Sox2, Klf4, and Myc) which the group reprogrammed to iPSCs using embryonic
stem cell CM (ESCM) supplemented with MAPK and GSK3 inhibitors as previously described [4, 5].