Not exact matches
This ability of nerves to modulate their chemical inputs, known as
synaptic plasticity, is especially high in developing brains but tends to become less intense in
adults.
Chronic fluoxetine stimulates maturation and
synaptic plasticity of
adult - born hippocampal granule cells.
We have previously shown ex-vivo its beneficial effect on
synaptic transmission and
plasticity in a mouse model of the OPHN1 loss of function.Here, we report that chronic treatment in
adult mouse with Fasudil, is able to counteract vertical and horizontal hyperactivities, restores recognition memory and limits the brain ventricular dilatation observed in Ophn1 - / y However, deficits in working and spatial memories are partially or not rescued by the treatment.
Neonatal isolation stress alters bidirectional long - term
synaptic plasticity in amygdalo - hippocampal synapses in freely behaving
adult rats