To understand the genetic control of postembryonic development, we performed a dominant screen for phenotypes affecting
the adult zebrafish.
In randomized experimental and data analysis protocols, MSI - 1346 has been shown to regenerate heart, connective, nerve, skin, bone and vascular tissues in
adult zebrafish.
Stem cells in
the adult zebrafish cerebellum: initiation and maintenance of a novel stem cell niche.
Molecular mechanisms of stem cell plasticity and regenerative neurogenesis in
adult zebrafish brain
A novel 3D method of locomotor analysis in
adult zebrafish: implications for automated detection of CNS drug - evoked phenotypes.
Julia Ganz (Brand, TUD)-- «Subdivisions and molecular characteristics if the neurogenic niches in
the adult zebrafish telecephalon» (2009)
A novel 3D method of locomotor analysis in
adult zebrafish: Implications for automated detection of CNS drug - evoked phenotypes, Journal of Neuroscience Methods 255 (30), 66 - 74.
Dorian Freudenreich (Brand, TUD)-- «Genetic cell lineage tracing and transcriptome analysis of neuronal progenitor cells during neurogenesis and regeneration of
the adult zebrafish telencephalon» (2010)
Sarah Hochmann (Brand, TUD)-- «The role of Fgf signaling in photoreceptor maintenance and degeneration in
the adult zebrafish retina» (2011)
To identify the molecular mechanisms of neural stem cell plasticity in
adult zebrafish brain after various types of tissue damage or physiological stimulations
Robust regeneration of
adult zebrafish lateral line hair cells reflects continued precursor pool maintenance.
Even the heart of
an adult zebrafish can regenerate after injury.
This is an image of
an adult zebrafish brain showing fluorescent granular perithelial cells (green) atop blood vessels (green).
Adult zebrafish are capable of regenerating their spinal cords after a complete severing injury.
Here Dr. Reimer and his team asked the question, «what happens to mature oligodendrocytes after a spinal cord injury in
adult zebrafish?».
These results placed the resident OPC population in the focus of interest: what are the signals that control and enable the activation of these precursor cells in
the adult zebrafish spinal cord?
Mark T. Keating and his colleagues at Harvard Medical School wounded the hearts of
adult zebrafishes by surgically removing 20 percent of the muscle from the lower chamber.
Not exact matches
Baier's experiments used
adult fish, whereas most
zebrafish screens use larvae.
Baier plans to use larval stages but he admits it is not clear yet whether the larval
zebrafish will react in the same way as the
adult mutants.
Research in the laboratory of Rebecca Wingert, the Gallagher Family Associate Professor of
Adult Stem Cell Research in the Department of Biological Sciences at the University of Notre Dame, has confirmed the key role of a certain small molecule in the development of kidney structures in
zebrafish, a widely used model for human kidneys.
Using gene therapy to insert the gene, they expressed the synthetic gene in
adult mice or in
zebrafish embryos, and witnessed remote activation of neurons the presence of a magnetic field through the altered behavior of the animals.
To investigate, microbiologist John Rawls and colleagues in Jeffrey Gordon's lab at Washington University School of Medicine in St. Louis, Missouri, turned to the
zebrafish, which remains transparent until it reaches an
adult length of about 1 to 2 centimeters.
The study, led by Yadong Wang, the William Kepler Whiteford Professor in Bioengineering in the Swanson School of Engineering and the principal investigator of the Biomaterials Foundry at Pitt, found that a single administration of extracellular matrices (ECM) from
zebrafish hearts restored the function of the heart and regenerated
adult mouse heart tissues after acute myocardial infarction.
Using gene therapy to insert the gene, they expressed the synthetic gene in
adult mice or in
zebrafish embryos, and witnessed remote activation of neurons in the presence of a magnetic field through the altered behavior of the animals.
To learn from
zebrafish how to enable the
adult brains to better cope with neurodegenerative disease and regenerate
My laboratory uses the
zebrafish to elucidate the genetic circuitry that controls regeneration of two organ systems in response to injury: the
adult heart and the caudal fin appendage.
Knowing that blastema formation is a key part of limb regeneration in animals with this capability as
adults, researchers Benjamin L King and Voot P Yin looked at three regenerative species — the
zebrafish, axolotl and the bichir — with the aim of finding out what genes control this event.
To do that we will activate the pathway in
adults of this
zebrafish model using gene manipulation techniques, then test the health of eye cells.
High - throughput imaging of
adult fluorescent
zebrafish with an LED fluorescence macroscope.
Developmental exposure of
zebrafish (Danio rerio) to bisphenol - S impairs subsequent reproduction potential and hormonal balance in
adults.