«New genetic method promises to
advance gene research, control insect pests.»
Not exact matches
Advances in molecular biology and bioinformatics have led to an explosion of
research on the causes of hearing loss and how to fix it with drugs or
gene therapy.
In our tests, the
Gene Knockout Kit gave us greater than 80 percent knock - out rates for seven targets,» shares Shondra Miller, Ph.D., Director, Center for
Advanced Genome Engineering at St. Jude Children's
Research Hospital, on Synthego's web site.
His
research has spanned hematopoiesis,
gene therapy, stem cell biology, genomics and cancer, consistently focusing on bringing the very latest
research advances to patients with heretofore incurable diseases.
Research on a new «gene editing» technology known as CRISPR — which theoretically allows any cell or organism to have its genome altered — is advancing exponentially, with early research ongoing on human embryos created for that
Research on a new «
gene editing» technology known as CRISPR — which theoretically allows any cell or organism to have its genome altered — is
advancing exponentially, with early
research ongoing on human embryos created for that
research ongoing on human embryos created for that purpose.
As
research advances, scientists hope to determine the precise location of a given
gene so they can test entire populations to identify carriers of the disease
gene.
Genes also play a role in menopause, and two
research teams have identified several
gene variants associated with
advancing or delaying menopause by as much as two years.
«Steep funding cuts for the federal health agencies are counterproductive at a time when innovative
research is moving us closer to identifying solutions for rare diseases, new prevention strategies to protect Americans from deadly and costly conditions,
advances in
gene therapy, new technologies for understanding the brain, and treatments that harness the ability of our immune system to fight cancer.»
Next week, the Intelligence
Advanced Research Projects Agency (IARPA), which is part of the Office of the US Director of National Intelligence, will hold a meeting about a planned funding programme for detecting genetically modified organisms that are potentially harmful, including ones that contain
gene drives.
These include the ability to bring new, innovative products to the market; progress in oncology, such as the approval of Genentech's drug Avastin for breast cancer and
advances in the use of
gene therapy, despite some setbacks; continuing progress in
research on stem cells; the emergence of treatments for previously untreated diseases; and solutions for food and fuel shortages, such as biocrops and biofuels.
«The use of a radiofrequency - driven magnetic field is a big
advance in remote
gene expression because it is non-invasive and easily adaptable,» says Dordick, who is Howard P. Isermann Professor of Chemical and Biological Engineering and vice president of
research at Rensselaer.
For his part, Collins, who has led NIH since 2009 and been kept on by the Trump administration, pointed to an array of promising NIH activities, including the development of new technologies to provide insights into human brain circuitry and function through the Brain
Research through
Advancing Innovative Neuroethologies (BRAIN initiative) and the use of the
gene - editing tool CRISPR - Cas9 to correct mutations and clear the way to develop and test a «curative therapy» for the first molecular disease: sickle cell disease.
«We look forward to conducting further
research through the STARTRK - 2 phase II trial and are hopeful that treatment with entrectinib in patients with a range of
advanced or metastatic solid tumors harboring NTRK1 / 2/3, ROS1, or ALK
gene fusions will result in very meaningful benefit.»
«Many
research groups are looking at how
genes are regulated from the perspective of which
genes need to be turned «on» for a cell to
advance to the next stage of development, but now we see that it's just as important to know which
genes need to be turned «off,»» Cook - Andersen said.
The experiments set off a debate about the safest way to do
gene drive experiments in the lab and helped prompt the Defense
Advanced Research Projects Agency and the Bill & Melinda Gates Foundation to support the academies's study.
Its report,
Gene Drives on the Horizon: Advancing Science, Navigating Uncertainty and Aligning Research with Public Values, stresses that although gene drive offers great promise for agriculture, conservation, and public health, neither the science nor the current regulatory system is adequate to address the risks and requirements of gene drive — altered organi
Gene Drives on the Horizon:
Advancing Science, Navigating Uncertainty and Aligning
Research with Public Values, stresses that although
gene drive offers great promise for agriculture, conservation, and public health, neither the science nor the current regulatory system is adequate to address the risks and requirements of gene drive — altered organi
gene drive offers great promise for agriculture, conservation, and public health, neither the science nor the current regulatory system is adequate to address the risks and requirements of
gene drive — altered organi
gene drive — altered organisms.
The
research, the cover story of this month's Science
Advances, builds upon previous studies from Dr. Olson in which CRISPR - Cas9 corrected a single
gene mutation that caused DMD in mice.
«This is the strongest evidence to date for lateral
gene transfer,» says molecular evolutionist Ford Doolittle of the Canadian Institute for
Advanced Research in Halifax, Nova Scotia.
One group of small, non-coding RNA molecules could serve as a marker to improve cancer staging and may also be able to convert some
advanced tumors to more treatable stages, report a University of Chicago - based
research team in the April 1, 2008, issue of the journal
Genes & Development.
While
advancing this target discovery work, deCODE will also bring to the alliance its Clinical Genome Miner ™ system in order to validate and prioritize targets emerging from Merck's substantial
research programs in mice and
gene - expression.
«Under this grant, we will utilize Lexicon's proprietary
gene knockout technology to study
genes that may impact the function of motor neurons to
advance treatments for spinal muscular atrophy,» said Brian P. Zambrowicz, Ph.D., executive vice president of
research at Lexicon.
He was awarded a European
Research Council
Advanced Investigator Grant (ERC) in 2009, the Outstanding Achievement Award from the American Society of
Gene and Cell Therapy (ASGCT) in 2014 and from ESGCT in 2015, an Honorary doctorate from the Vrije University, Brussel, in 2015, the Jimenez Diaz Prize in 2016, and the Beutler Prize from the American Society of Hematology (ASH) in 2017.
In 1999, with his PhD in hand, Dr. Malik took the postdoc track to Seattle, Washington, for a position at the Fred Hutchinson Cancer
Research Center, where he began work with investigator Steven Henikoff on centromeres (repetitive sequences of DNA that do not code for proteins),
advancing his hypotheses on evolutionary
gene conflict.
From the development of insulin and transplant surgery to modern day
advances, including
gene therapies and cancer treatments; animals — from mice to monkeys — continue to play a crucial role in both basic and applied
research.
Research on the most tractable models, such as Drosophila, is greatly
advancing our understanding of what specific
genes do, including many directly relevant to human biology and medicine.
Study using disabled form of HIV in
gene therapy wins highest award from Clinical
Research Forum; others cited for
advances revealing damage caused by long - term cortisone shots to treat arthritic knees; and
gene replacement therapy for infants with deadly neuromuscular disease
Taking advantage of
research progress and
advanced gene sequencing technology, Brown University will join a consortium of European researchers for a three - year, $ 2.9 - million study of how fertilization has evolved in flowering plants.
Review: The role of operating parameters and oxidative damage mechanisms of
Advanced Chemical Oxidation Processes in the combat against antibiotic - resistant bacteria and resistance
genes present in urban wastewater — I. Michael - Kordatou — Water
Research
Cenix BioScience is a contract
research organization focused on the discovery and pre-clinical development of novel therapeutics, specializing in
advanced applications of RNA interference (RNAi)
gene silencing combined with high content phenotyping in cultured cells in vitro and in animals in vivo.
The focus of Dr. Smoller's
research interests has been 1) understanding the genetic and environmental determinants of psychiatric disorders across the lifespan; 2) integrating genomics and neuroscience to unravel how
genes affect brain structure and function; and 3) using «big data», including electronic health records and genomics, to
advance precision medicine.
The team received a total of 12 million hours on two of DOE's
Advanced Scientific Computing
Research's supercomputers: the Cray XTs at Oak Ridge National Laboratory and the IBM Blue
Gene / P at Argonne National Laboratory.
University of Pennsylvania immunotherapy researcher Dr. Carl June, who led the development of an experimental therapy for
advanced childhood leukemia that is expected to become the first CAR T - cell therapy to win U.S. Food and Drug Administration approval, will give the keynote talk today at the Conference on Cell &
Gene Therapy for HIV Cure at Fred Hutchinson Cancer
Research Center.
This latest development in
gene therapy is the result of more than two decades of painstaking genetic
research by Jean Bennett, MD, PhD, and Albert M. Maguire, M.D., both Professors of Ophthalmology and Co-directors of the Center for
Advanced Retinal and Ocular Therapeutics at Penn Medicine.
Tags: Dr Vincent Chung, Dr Yuman Fong, Liver cancer, cancer
research advances,
gene therapy, immunotherapy, viral
gene therapy
The CRISPR - Cas9 system and later
advances, also developed by Zhang, are easy to execute with almost endless possibility for new
research enabling scientists to change, delete, and replace any
genes of any animal.
Advances in Culture and Diversity in Prevention Science Award
Gene Brody, PhD (see photo and bio) Director The Center for Family
Research The University of Georgia