Format: Website Years Covered: Jan. 2011 - Dec. 2017 Search Strategy: Manually search a dozen registries by keywords Project Focus: any trials of
advanced cell therapy, worldwide
Package of
ALL advanced cell therapy trials registered internationally during 2017 contains 18 parameters for 638 trials and comes with free updates if we find more trials in this time frame.
NEW: This data set provides the sponsor and collaborators, lead investigator (s), and participating hospitals for
all advanced cell therapy trials registered worldwide in 2017.
Monthly updates of 18 parameters for all new trials in
advanced cell therapy.
When I started this project with PGCBF, we decided to use definition of
Advanced Cell Therapy to set inclusion and exclusion criteria for the most comprehensive data capture.
Format: Website Years Covered: Cumulative to 31 October 2017 Search Strategy: Manually search a dozen registries by keywords Project Focus: On - line search portal of all currently recruiting cord blood trials, both
advanced cell therapy and standard hematology / oncology, worldwide
Format: Website Years Covered: currently active UK trials as of June 2017 Search Strategy: Not disclosed Project Focus:
advanced cell therapy, active that year, in the UK only Special Notes: on - line sort by 4 parameters, archives for previous years back to 2012.
NEW: Package of MSC
advanced cell therapy trials registered internationally during 2017 contains 16 parameters for 145 trials.
We define
Advanced Cell Therapy as all therapies in which cells are more than minimally manipulated, and / or their action is not homologous.
This project is presented in the Pioneer
Advanced Cell therapy of the Epidermis (PACE) booklet.
In the last decade
advanced cell therapies are becoming highly commercialized.
Not exact matches
«As a part of the Nohla team, I look forward to
advancing the development of its
cell therapy programs for patients with significant unmet needs.»
His research has spanned hematopoiesis, gene
therapy, stem
cell biology, genomics and cancer, consistently focusing on bringing the very latest research
advances to patients with heretofore incurable diseases.
Using
advances in genomic sequencing, the human microbiome, proteomics, informatics, computing, and
cell therapy technologies, HLI is building the world's most comprehensive database of human genotypes and phenotypes as a basis for a variety of commercialization opportunities to help solve aging related disease and human biological decline.
We are identifying and supporting work on the technologies of the future: in
advanced manufacturing; renewable energy;
cell therapy; interconnected digital; intelligent transport; and next generation computing.
A group of the nation's leading cancer research scientists and their Cuban counterparts are exploring how to
advance cancer
therapy, diagnosis, and prevention, including the use of immunotherapy to harness the body's immune systems to attack and eliminate cancer
cells.
Based on results of the current study described in a report online June 18 in the journal Cancer
Cell, Johns Hopkins researchers say they are planning a phase I clinical trial to test the paclitaxel - fostamatinib combination
therapy in patients with recurrent
advanced ovarian cancer.
Advanced Cell Technology, based in Santa Monica California, is developing embryonic stem cell therapies for macular degeneration and other conditions using cells obtained non-destructively from an early embryo called a blastoc
Cell Technology, based in Santa Monica California, is developing embryonic stem
cell therapies for macular degeneration and other conditions using cells obtained non-destructively from an early embryo called a blastoc
cell therapies for macular degeneration and other conditions using
cells obtained non-destructively from an early embryo called a blastocyst.
The Sartorius & Science Prize for Regenerative Medicine &
Cell Therapy is an annual prize geared toward researchers focused on basic or translational research that advances regenerative medicine and cell ther
Cell Therapy is an annual prize geared toward researchers focused on basic or translational research that advances regenerative medicine and cell t
Therapy is an annual prize geared toward researchers focused on basic or translational research that
advances regenerative medicine and
cell ther
cell therapytherapy.
New products and developments, such as new drugs for cancer, fresh
therapies for rare diseases, progress in medications for HIV / AIDS, and
advances in stem
cell research had the greatest positive impact.
These include the ability to bring new, innovative products to the market; progress in oncology, such as the approval of Genentech's drug Avastin for breast cancer and
advances in the use of gene
therapy, despite some setbacks; continuing progress in research on stem
cells; the emergence of treatments for previously untreated diseases; and solutions for food and fuel shortages, such as biocrops and biofuels.
«The discovery of the novel progenitor represents a fundamental
advance in this field and potentially to the liver regeneration field using
cell therapy,» said the study's senior author, Valerie Gouon - Evans, PharmD, PhD, Assistant Professor, in the Department of Developmental and Regenerative Biology, Black Family Stem Cell Institute, at the Icahn School of Medicine at Mount Si
cell therapy,» said the study's senior author, Valerie Gouon - Evans, PharmD, PhD, Assistant Professor, in the Department of Developmental and Regenerative Biology, Black Family Stem
Cell Institute, at the Icahn School of Medicine at Mount Si
Cell Institute, at the Icahn School of Medicine at Mount Sinai.
For his part, Collins, who has led NIH since 2009 and been kept on by the Trump administration, pointed to an array of promising NIH activities, including the development of new technologies to provide insights into human brain circuitry and function through the Brain Research through
Advancing Innovative Neuroethologies (BRAIN initiative) and the use of the gene - editing tool CRISPR - Cas9 to correct mutations and clear the way to develop and test a «curative
therapy» for the first molecular disease: sickle
cell disease.
Treatment for
advanced melanoma has seen success with targeted
therapies — drugs that interfere with division and growth of cancer
cells by targeting key molecules — especially when multiple drugs are used in combination.
With a history of public blunders, can
Advanced Cell Technology make embryonic stem - cell therapies a real
Cell Technology make embryonic stem -
cell therapies a real
cell therapies a reality?
The technical
advances emerging from gene
therapy have fueled the larger fields of
cell and immune
therapy, where DNA, immune molecules, and viruses are all elements to be manipulated, in concert or one at a time.
While the disease can take many forms, recent
advances have better characterized how lymphoma
cells proliferate and interact with other
cells and tissues, leading to the development of powerful, targeted
therapies with fewer side effects than traditional approaches.
The journal's home page explains that translational medicine «builds on basic research
advances — studies of biological processes using
cell cultures, for example, or animal models — and uses them to develop new
therapies or medical procedures.»
The new study shows that a «constitutively active» signaling circuit can trigger
cells to grow into tumors and drive
therapy resistance in
advanced prostate cancer.
Advances in understanding the
cells and molecules that transmit pain signals are providing new targets for drugs that could relieve various kinds of pain — including those poorly controlled by existing
therapies
Hematopoietic stem
cell transplantation (HSCT), once considered an effective yet risky alternative to drug
therapy for blood cancer, has become more accessible and successful in a wide range of patients as a result of major
advances in transplant strategies and technologies.
Results from a clinical trial investigating a new T
cell receptor (TCR)
therapy that uses a person's own immune system to recognize and destroy cancer
cells demonstrated a clinical response in 80 percent of multiple myeloma patients with
advanced disease after undergoing autologous stem
cell transplants (ASCT).
«Because of relatively low survival rates and their
advancing age, these patients tend to be poor candidates for aggressive
therapies, like a bone marrow transplant,» said senior author Catriona Jamieson, MD, PhD, professor of medicine, chief of the Division of Regenerative Medicine at UC San Diego School of Medicine and director of the Stem
Cell Research Program at Moores Cancer Center.
This technological
advance will provide investigators with a new tool for comprehensive mapping of
cell -
cell communication, which is important in all aspects of cancer development, maintenance, and response to
therapy.
While neural stem
cell therapies are already
advancing to clinical trials, this research raises cautionary notes about moving to human
therapy too quickly, said Tuszynski.
In recent clinical trials, CAR T
cell therapy has dramatically improved the outcomes of blood cancer patients with
advanced, otherwise untreatable forms of leukemia and lymphoma.
Discovery of a novel,
advanced technique to identify the rare
cells where human immunodeficiency virus (HIV) hides in patients taking antiretroviral
therapy (ART).
«Stem
cell transplants may
advance ALS treatment by repair of blood - spinal cord barrier: ALS mice improved with stem
cell therapy; first step for science in finding better treatment.»
NRG Oncology researchers recently developed and validated a nomogram that can predict 2 - year and 5 - year overall survival (OS) and progression - free survival (PFS) for patients with local - regionally
advanced oropharyngeal squamous
cell carcinoma (OPSCC) treated primarily with radiation - based
therapy.
So for 17 patients with
advanced melanoma who didn't have tumor - fighting T
cells and had failed existing treatments, Rosenberg's team tried gene
therapy.
That's the question raised by some perplexing new studies, providing another complication for researchers who are trying to develop
advanced therapies based on neurons grown from stem
cells.
Recent
advances have raised expectations that diseases of the CNS may be improved by the use of stem
cell therapies.
Researchers enrolled 102 patients in with
advanced non-small
cell lung cancer in the phase 1b study to evaluate the durvalumab and tremelimumab combination
therapy.
The ability to make expand the number of iNKT
cells is expected to
advance cancer
therapies.
But there's reason for optimism - recent
advances in screening and treatment, such as CAR T
cell therapy, mean patient outcomes and quality of life are continuing to improve.
The Okyanos Center for Regenerative Medicine was founded in 2011 to offer patients the most
advanced and safe medical treatments in regenerative medicine, and to partner with leading universities and research labs in collecting data that
advances the field of stem
cell therapy.
ARandomized, Phase III, Double - Blind Placebo - Controlled Trial of Sunitinib as Maintenance
Therapy in Non-Progressing Patients following an Initial Four Cycles of Platinum - Based Combination Chemotherapy in
Advanced, Stage IIIB / IV Non-Small
Cell Lung Cancer
The NSU
Cell Therapy Institute is housed in the university's newly opened $ 100 million, Center for Collaborative Research (CCR), which is one of the largest (215,000 square feet) and most
advanced research facilities in Florida.
Besides being a potentially important
advance for the patients with the greatest needs, PEC - Direct is also considered a stepping stone to
cell therapy for all insulin requiring patients.
Housed in NSU's Center for Collaborative Research, the NSU
Cell Therapy Institute focuses on
advancing new approaches to cancer immunotherapy and regenerative medicine