Not exact matches
When
patients with
advanced ovarian cancer become resistant to one drug, clinicians usually prescribe a new drug.
Based on results of the current study described in a report online June 18 in the journal
Cancer Cell, Johns Hopkins researchers say they are planning a phase I clinical trial to test the paclitaxel - fostamatinib combination therapy in patients with recurrent advanced ovarian c
Cancer Cell, Johns Hopkins researchers say they are planning a phase I clinical trial to test the paclitaxel - fostamatinib combination therapy in
patients with recurrent
advanced ovarian cancercancer.
Paclitaxel and another chemotherapy drug, carboplatin, are considered standard, first - line treatments for
advanced ovarian cancer, experts say, and most
patients respond to the drugs initially.
«Personalized tumor vaccine shows promise in pilot trial: Vaccine against
patients» own tumors triggers a broad response, and induced five - year remission in one
patient with
advanced ovarian cancer.»
Technology developed at Western University and Lawson Health Research Institute can provide a new window into whether or not
patients are responding to treatment for
advanced ovarian cancer.
The study was done on 10
patients in
advanced stages of
ovarian cancer.
«One in five women with
ovarian cancer does not undergo surgery, study reveals: Results show survival benefit of surgery for
patients regardless of age or
advanced disease, and point to barriers to
cancer care delivery.»
• Diagnostic laparoscopy for all surgically fit
patients with suspected
advanced - stage
ovarian cancer.
Though smaller in number, some
patients with
advanced disease and carrying a BRCA mutation may benefit from the same targeted therapy being used today in the clinic to successfully treat some
ovarian cancer patients.»
The drugs are already approved for treatment of
patients with
advanced breast
cancer as well as
ovarian, pancreatic and certain lung
cancers.
The poor survival in
advanced ovarian cancer is due both to late diagnosis, as well as to the lack of effective second - line therapy for
patients who relapse.
Despite
advances in surgery and chemotherapy over the past 20 years, only modest progress has been made in improving overall survival in
patients with
ovarian cancer.
Most
patients diagnosed with
advanced ovarian cancer develop platinum resistant / refractory disease.
The LION trial randomized 650
patients with
advanced epithelial
ovarian cancer and macroscopic complete resection to either systematic pelvic and para-aortic LNE (323
patients in intention - to - treat cohort), or no LNE (324
patients in intention - to - treat cohort).
Systematic lymphadenectomy in
patients with
advanced ovarian cancer and complete resection does not improve progression - free or overall survival, and should be omitted, according to results of a new study.
«Upfront surgery aiming at macroscopic complete resection is the goal in
patients with primary
advanced ovarian cancer,» said Philipp Harter, MD, PhD, of the Kliniken Essen - Mitte in Germany, during his presentation of the LION study (abstract 5500) at the 2017 American Society of Clinical Oncology (ASCO) Annual Meeting.
Systematic lymphadenectomy (LNE) in
patients with
advanced ovarian cancer and complete resection does not improve progression - free or overall survival (OS), and should be omitted, according to results of a new study.
JCO retracted paper «An Integrated Genomic - Based Approach to Individualized Treatment of
Patients With
Advanced - Stage
Ovarian Cancer» — statistician: Mike West
New Standard of Care A 50 - year - old method for delivering chemotherapy directly into the abdomen was reevaluated for
patients with
ovarian cancer after a seven - year study of more than 400
patients revealed increased survival rates in
patients with
advanced ovarian cancer.
We have made progress in the safe use of
advanced surgical procedures and can now combine surgery with heated intraperitoneal chemotherapy for selected
patients with
ovarian cancer.
May 20, 2015 Study adds diabetes drug with anti-
cancer effect to
ovarian cancer treatment Several recent studies have suggested that metformin, an established drug developed to treat
patients with type II diabetes, may provide significant benefits, including increased survival, to
patients being treated for
advanced cancers.