Sentences with phrase «advanced stage trials»

RISQ Group is in advanced stage trials with several other platforms.

Not exact matches

But a late - stage clinical trial called CheckMate - 026 for the drug failed to meet its primary goal of halting cancer progression in advanced, untreated patients whose tumors consisted of at least 5 % PD - L1.

If you're suffering from advanced stages of cancer the best news your oncologist can deliver, apart from saying you're winning the battle, is that you're eligible for a promising new drug trial.

ZURICH (Reuters)- Roche's Tecentriq immuno - oncology drug failed a late - stage follow - up trial against advanced bladder cancer, the Swiss drugmaker said on Wednesday, raising questions about whether regulators could scale back their approval of the medicine.

This is the basic principle behind the RTS, S vaccine, and while the clinical trial results have been somewhat disappointing, RTS, S is one of the few candidate vaccines to reach such an advanced stage.

Trial participants have advanced disease with geography atrophy — considered a late stage in dry AMD — and very poor visual abilities.

But most large clinical trials of ACEI / ARB exclude patients with the most advanced stage of CKD predialysis, perhaps out of concern that the drugs can cause renal failure and the need for dialysis, so it remains unclear whether that therapy is effective in patients with advanced CKD, according to the study background.

Such a system will enable ethical and more rapid and accurate testing of experimental drugs before the clinical trial stage and advance studies of genetic and environmental causes of central nervous system disorders.

ARandomized, Phase III, Double - Blind Placebo - Controlled Trial of Sunitinib as Maintenance Therapy in Non-Progressing Patients following an Initial Four Cycles of Platinum - Based Combination Chemotherapy in Advanced, Stage IIIB / IV Non-Small Cell Lung Cancer

In this original article on the treatment of advanced stage Hodgkin lymphoma, the German Hodgkin Study Group updated their initial findings on the HD15 trial.

A Phase II Single - Arm Trial to Investigate Tepotinib in advanced (Stage IIIB / IV) Non-Small Cell Lung Cancer with MET Exon 14 (METex14) Skipping Alterations After Failure of at Least One Prior Active Therapy, Including a Platinum - Doublet - Containing Regimen

For more information regarding Bristol - Myers Squibb Clinical Trial participation, please visit www.BMSStudyConnect.com Inclusion Criteria: • Early stage IB - IIIA, operable non-small cell lung cancer, confirmed in tissue • Lung function capacity capable of tolerating the proposed lung surgery • Eastern Cooperative Oncology Group (ECOG) Performance Status of 0 - 1 • Available tissue of primary lung tumor Exclusion Criteria: • Presence of locally advanced, inoperable or metastatic disease • Participants with active, known or suspected autoimmune disease • Prior treatment with any drug that targets T cell co-stimulations pathways (such as checkpoint inhibitors) Other protocol defined inclusion / exclusion criteria could apply

The ultimate goal is to develop new and better approaches for genetic engineering of stem cells to be tested within a clinical trial for the treatment of late stage advanced cancers.

And both immunotherapies are now advancing through early - stage human clinical trials.

Another mouse preclinical screening trial targeted the symptomatic stage (between 9 and 11 months)[44] and a study with a plant extract [99] used 23 - to 24 - month - old mice, but to our knowledge no chemically defined AD drug candidate has been tried at the more pathologically advanced stage used in this study.

Our pipeline is a diversified combination of internal and out - licensed programmes, which vary in their stages of development from discovery to advanced clinical trials.

A pilot phase II trial of hu14.18 K322A (anti-GD-2) ⎯ given in combination with chemotherapy, radiation therapy, and cell transplants ⎯ for children with advanced stage neuroblastoma (NCT01857934).

Escalated BEACOPP Plus Rituximab in Advanced Hodgkin Lymphoma Fails to Improve Outcomes: The results of the phase III HD18 trial by the German Hodgkin Study Group determined that the addition of rituximab to an escalated regimen of BEACOPP did not improve progression - free survival (PFS) in patients with advanced - stage Hodgkin lAdvanced Hodgkin Lymphoma Fails to Improve Outcomes: The results of the phase III HD18 trial by the German Hodgkin Study Group determined that the addition of rituximab to an escalated regimen of BEACOPP did not improve progression - free survival (PFS) in patients with advanced - stage Hodgkin ladvanced - stage Hodgkin lymphoma.

As part of the NCTN, the Kimmel Cancer Center partners on government - funded clinical trials in more advanced stages of development.

MasterKey265 is a combination phase I / III trial that is now open at Roswell Park and 160 other locations throughout the world for patients with advanced melanoma (stage IIIB to IVM1c) who can not be treated with surgery alone.

Both the ovarian and prostate cancer trials could change clinical practice, with more women taking the drug bevacizumab (Avastin) to combat the disease in its advanced stages and more men getting radiation therapy for locally advanced prostate cancer, according to researchers who presented the findings Sunday at the American Society of Clinical Oncology (ASCO) annual meeting in Chicago.

Grape skin and grape seed extracts have been shown to reverse the signs of aging and also to improve brain functions enough to advance resveratrol into the final stages of clinical trials as an Alzheimer drug candidate.

[I] n light of advances in technology allowing greater access to information that can inform a trial court about the past litigation history of venire members, it is appropriate to place a greater burden on the parties to bring such matters to the court's attention at an earlier stage.

At Goodman Law, we have the experience, knowledge and confidence to advance a case through the various stages of the lawsuit and all the way to trial.

In his August 31, 2010 New York Law Journal article, Court Rule Altered to Buttress E-Discovery; I - Filing Advances, Joel Stashenko discusses the amended Uniform Rules of Trial Courts of the State of New York as an effort to insure that lawyers keep «up to speed» regarding their clients» records at the early stages of discovery.