Sentences with phrase «advancing genetic studies»

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A degree of kinship between human beings and the rest of physical creation has always been clear to an extent, but the depth and detail of our interrelationship with the rest of life on the planet is being confirmed over and over again in breathtaking detail by new scientific advances such as genetic studies and molecular biology.

The field had a rocky start after companies overhyped its potential, but with advances in genetic sequencing, and a slew of new studies, the concept is in for a reboot.

In this way, Warner said, the study advances the goal of personalized medicine, to diagnose conditions earlier and provide the most effective treatment based on patients» genetic and phenotypic characteristics.

«This study provides a new example of how genetic analysis can be a valuable and powerful tool to advance our knowledge of human history.»

Even as advances in ancient - DNA technology have made it possible to probe population mixing and large - scale migrations that occurred thousands of years ago, researchers have had trouble studying the genetic history of the Near East because the region's warm climate has degraded much of the DNA in unearthed bones.

He mentioned mouse studies by Chris Fiorillo, now at the Korea Advanced Institute of Science and Technology (KAIST), who inserted genetic sequences that code for a light - sensitive protein called channelrhodopsin - 2 into dopamine - producing neurons of mice.

The first big advance occurred in the early 1990s, when epidemiological studies revealed that 90 to 95 percent of individuals with the disorder carry a genetic marker associated with autoimmune disease — self - inflicted damage that occurs when the body mistakes its own tissues for a foreign invader and attacks them.

Uncovering the genetic pathogenesis of Alzheimer's disease has been a target of great interest over the past few years, and genome - wide mapping studies focusing on risk genes have led to significant advances in the field.

«In the space of just five years, reasonably affordable studies using DNA sequencing have advanced from using only a handful of genetic markers to more than 2,000 — an unbelievable amount of DNA,» adds Simison.

Advances in morphological and genetic studies have since revealed two species of orang - utan, however, on the islands of Borneo and Sumatra.

Such a system will enable ethical and more rapid and accurate testing of experimental drugs before the clinical trial stage and advance studies of genetic and environmental causes of central nervous system disorders.

Of the 22 patients whose tumors successfully grafted, six died before data from the mice were available, but in 13 of the remaining 16 cases, there was a positive correlation between mouse and human results.2 In a second study, performed in collaboration with Manuel Hidalgo of the Spanish National Cancer Research Center, the team found that 6 of 13 patients with advanced solid tumors who were treated based on results from personalized PDX mice had partial tumor remissions, even in cases where genetic sequencing of the tumor showed no actionable mutations.3

The JCVI GCID aims to study pathogens and the genetic determinants of their virulence, drug - resistance, immune evasion and interactions with the host, and host microbiome to advance research in pathogenicity, drug - resistance, disease transmission and vaccine development.

Dr. Jos Jonkers» research group studies the genetic basis of human breast cancer, using advanced mouse models for p53 - induced breast cancer, BRCA1 - and BRCA2 - associated hereditary breast cancer, and E-cadherin mutated invasive lobular carcinoma.

Studies to improve the knowledge of genetic diseases include the natural history study for MLD, advanced diagnosis and natural history of primary immunodeficiencies and immunedysregulatory disorder, and immune reconstitution after hematopoietic stem cell transplantation for genetic disorders.

Diversity in Genomics Research Cohorts The lack of diversity within participant cohorts in genetics and genomics research limits our ability to study variation across the human genome and the genetic factors that influence health and disease, as well as our ability to ensure that every segment of the population is able to benefit from advances stemming from the research.

Important reports from the Weiner lab include the first DNA vaccine studied for HIV as well as for cancer immune therapy of cutaneous T cell lymphoma, the early development of DNA encoded genetic adjuvants, including IL - 12, advances in gene optimization, and advances in electroporation technologies resulting in improved gene delivery.

ASHG 2008: Advancing Our Understanding of Genetic Disease: New Findings from Genome - Wide Association Studies ASHG Press Release - November 12, 2008

The aim of the Deciphering Developmental Disorders (DDD) Study is to advance clinical genetic practice for children with developmental disorders by the systematic application of the latest microarray and sequencing methods while addressing the new ethical challenges raised.

«This study has a relatively simple message: those with advanced prostate cancer should consider genetic testing both to help their own treatment and also so family members can take preventive action,» says Dr. Kenneth Offit, chief of clinical genetics at Memorial Sloan Kettering Cancer Center (MSKCC) and a co-author of the study.

The purpose of this study was to characterize this disease with advanced imaging techniques and identify the genetic components.

The study, published in Journal of the American Veterinary Medical Association, provides a better understanding of the prevalence and source of such disorders, and could advance efforts to prevent and treat genetic disorders in both dogs and humans, the researchers say.

Genetic resources have a critical role to play in feeding the world — especially as climate change advances faster than expected — and much more needs to be done to study, preserve and utilize the biological diversity that underpins world food production, according to a new book released by FAO today.