On the contrary, I believe there should be freedom of energy use and selection as long as there are no significant
adverse effects on others.
... one front of mission can not be neglected or denied without
adverse effect on other fronts; and already the domestic agencies of the churches are being afflicted with blight and malnutrition.
While the move has resulted in an increase in production from the Carolina offense, it has had a nearly equally
adverse effect on the other end.
Although this analysis does not consider the possibility that a greater concentration of high - risk students could have
adverse effects on other students, it nonetheless highlights the likely beneficial consequences of giving preference to disadvantaged students in the admissions process for oversubscribed schools.
This is not only because stability indicators have the highest single scores, but also because factors defining stability spread to have
an adverse effect on other categories,» said the report.
The high levels of thyroid hormone can have
adverse effects on other organ systems.
This would then impact negatively on the relationship of the father and child and have
an adverse effect on other areas in which the parents would need to co-operate in the best interests of the child (such as schooling).
Not exact matches
Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses
on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the
effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the
effect of global economic conditions
on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the
effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or
other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our
other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and
other customers, and the risk of nonpayment by such customers; 13) any
adverse impact
on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any
adverse impact
on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or
other security attacks, information technology failures, or
other disruptions; 16) returns
on pension plan assets and the impact of future discount rate changes
on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco
on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and
other aerostructures suppliers; 19) the
effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the
effect of changes in tax law, such as the
effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted
on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the
effect of such changes; 21) any reduction in our credit ratings; 22) our dependence
on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and
other governments
on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest
on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and
other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses,
adverse changes to business relationships and
other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among
other things.
These risks and uncertainties include, among
others: the unfavorable outcome of litigation, including so - called «Paragraph IV» litigation and
other patent litigation, related to any of our products or products using our proprietary technologies, which may lead to competition from generic drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence of efficacy and adequacy of bridging to buprenorphine; clinical development activities may not be completed
on time or at all; the results of our clinical development activities may not be positive, or predictive of real - world results or of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make
adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights of third parties, or have unintended side
effects,
adverse reactions or incidents of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report
on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available
on the SEC's website at www.sec.gov.
The Healthcare Reform Law, including The Patient Protection and Affordable Care Act and The Healthcare and Education Reconciliation Act of 2010, could have a material
adverse effect on Humana's results of operations, including restricting revenue, enrollment and premium growth in certain products and market segments, restricting the company's ability to expand into new markets, increasing the company's medical and operating costs by, among
other things, requiring a minimum benefit ratio
on insured products, lowering the company's Medicare payment rates and increasing the company's expenses associated with a non-deductible health insurance industry fee and
other assessments; the company's financial position, including the company's ability to maintain the value of its goodwill; and the company's cash flows.
These risks and uncertainties include competition and
other economic conditions including fragmentation of the media landscape and competition from
other media alternatives; changes in advertising demand, circulation levels and audience shares; the Company's ability to develop and grow its online businesses; the Company's reliance
on revenue from printing and distributing third - party publications; changes in newsprint prices; macroeconomic trends and conditions; the Company's ability to adapt to technological changes; the Company's ability to realize benefits or synergies from acquisitions or divestitures or to operate its businesses effectively following acquisitions or divestitures; the Company's success in implementing expense mitigation efforts; the Company's reliance
on third - party vendors for various services;
adverse results from litigation, governmental investigations or tax - related proceedings or audits; the Company's ability to attract and retain employees; the Company's ability to satisfy pension and
other postretirement employee benefit obligations; changes in accounting standards; the
effect of labor strikes, lockouts and labor negotiations; regulatory and judicial rulings; the Company's indebtedness and ability to comply with debt covenants applicable to its debt facilities; the Company's ability to satisfy future capital and liquidity requirements; the Company's ability to access the credit and capital markets at the times and in the amounts needed and
on acceptable terms; and
other events beyond the Company's control that may result in unexpected
adverse operating results.
For example, the expected timing and likelihood of completion of the proposed merger, including the timing, receipt and terms and conditions of any required governmental and regulatory approvals of the proposed merger that could reduce anticipated benefits or cause the parties to abandon the transaction, the ability to successfully integrate the businesses, the occurrence of any event, change or
other circumstances that could give rise to the termination of the merger agreement, the possibility that Kraft shareholders may not approve the merger agreement, the risk that the parties may not be able to satisfy the conditions to the proposed transaction in a timely manner or at all, risks related to disruption of management time from ongoing business operations due to the proposed transaction, the risk that any announcements relating to the proposed transaction could have
adverse effects on the market price of Kraft's common stock, and the risk that the proposed transaction and its announcement could have an
adverse effect on the ability of Kraft and Heinz to retain customers and retain and hire key personnel and maintain relationships with their suppliers and customers and
on their operating results and businesses generally, problems may arise in successfully integrating the businesses of the companies, which may result in the combined company not operating as effectively and efficiently as expected, the combined company may be unable to achieve cost - cutting synergies or it may take longer than expected to achieve those synergies, and
other factors.
As a result, political instability, labor strikes, natural disasters or
other events resulting in the disruption of trade or transportation from
other countries or the imposition of additional regulations relating to duties upon imports could cause significant delays or interruptions in the supply of our merchandise or increase our costs, either of which could have an
adverse effect on our business.
«Negative publicity or public opinion resulting from these matters may increase the risk of reputational harm to our business, which can impact our ability to keep and attract customers, our ability to attract and retain qualified team members, result in the loss of revenue, or have
other material
adverse effects on our results of operations and financial condition.»
There are
other aspects of the NGP Report that merit further discussion, including its approach to adaptive management (we now have three different JRP reports in as many years that take different views
on the extent to which AM can be relied upon in making a determination as to the likelihood of significant
adverse environmental
effects under CEAA), the precautionary principle, species at risk and Aboriginal consultation.
The Enterprise Compensation Committee discharges the board of directors» responsibilities relating to the compensation of our executives and directors; reviews and discusses with management the Compensation Discussion and Analysis and performs
other reviews and analyses and makes additional disclosures as required of compensation committees by the rules of the SEC or applicable exchange listing requirements; provides general oversight of our compensation structure, including our equity compensation plans and benefits programs, and confirms that these plans and programs do not encourage risk taking that is reasonably likely to have a material
adverse effect on Hewlett Packard Enterprise; reviews and provides guidance
on our human resources programs; and retains and approves the retention terms of the Enterprise Compensation Committee's independent compensation consultants and
other independent compensation experts.
Like
other secured cards, maxing out and missing payments has an
adverse effect on the customer's score.
The
effects on the US share market,
on the
other hand, have been mixed: there have been some benefits from lower interest rates but the profit results of US companies are increasingly showing signs of
adverse impacts from Asian competition.
The problems like these that arise from BC pills, or shots, are far smaller then the
adverse side
effects of almot every
other med
on the market.
In
other parts of the world, he explains, farms use a lot of mechanization and industrialization to produce large quantities of abalone, but this has an
adverse effect on their flavor.
«While Mobil Oil Australia does not accept that its previous subscription, or the subscription of
others, to the Oil PriceWatch service had any
adverse effect on competition n any relevant market in Australia, Mobil Oil Australia has voluntarily and without admission offered to provide this Undertaking to address the concerns raised by the ACCC.»
This of course also does not take in to consideration any of the many possible downsides eg: would Martinez as our centre forward have any
adverse effect on the goalscoring capability of
others like Alexis or Ramsey?
This study and
others like it help to show that there exists in children's lives a whole spectrum of environmental factors that fall short of the traditional definition of trauma but still have an
adverse effect on brain development.
When
adverse effects were found, they were «inconsistent from one study to the
other, always relatively minor, and appear to have no impact
on infant health or mortality.»
In comparison to
other 6 year old children who had similar sleep problems in infancy but were not given such interventions, the sleep - trained children showed no
adverse effects on their emotional and behavioral development or
on their relationship with their parents.
It is thought, however, that levels of these fatty acids at levels greater than those found in human breast milk may have
adverse effects on growth, survival, and neurodevelopment in
other animals.
After they're breathing
on their own (or even if they did from the start), these babies may have continuing breathing problems — because of delayed lung development or
other adverse effects of nicotine.
These findings are all consistent with the growing body of literature
on the impact of
adverse childhood experiences
on neurological, cognitive, emotional and social development, as well as physical health.38 Although some studies have found no relation between physical punishment and negative outcomes, 35 and
others have found the relation to be moderated by
other factors, 12 no study has found physical punishment to have a long - term positive
effect, and most studies have found negative
effects.17
After they are breathing
on their own, or even if they did from the start, these babies may have continuing breathing problems, because of delayed lung development or
other adverse effects of nicotine.
Among
other things, residents are worried about the health impacts of adding Cortland County's trash to the incinerator, suggesting dioxins coming from the plant have already had
adverse health
effects on residents.
Seventy per cent of the websites provided information
on the safe usage of prescription medications, including potential side
effects or
adverse reactions when combined with
other drugs.
«Our research shows that trade extends the distance between cause and
effect by separating consumers in one region and people who suffer
adverse health impacts, who are often
on the
other side of the world.»
We also forced motor neurons to express
other Hox genes and exposed them to retinoic acid, both of which had a dramatically
adverse effect on their differentiation.
We know from
other research that the period between early adolescence and young adulthood is a sensitive period for weight gain that has
adverse effects on cardiovascular health later in life.»
Application is an environmental issue in industrialized countries like the United States because of high energy input, increased greenhouse gas emissions, water pollution and
other adverse effects on ecosystems and human health.
«There is a growing consensus in the scientific community that small doses of pesticides and
other chemicals can have
adverse effects on health, especially during vulnerable periods such as fetal development and childhood,» reports author and physician Andrew Weil, a leading voice for so - called integrative medicine combining conventional and alternative medical practices.
ASH is alarmed about the opioid crisis; however, it is concerned about potential
adverse effects that policy changes could have
on the administration of necessary and appropriate pain medicine for patients with hematologic conditions such as sickle cell disease (SCD), blood cancers, and
other bleeding disorders.
Further research is needed to determine whether
other variables of ultrasound exposure also have
adverse effects on the developing fetus.
With the microRNA signatures of mitochondrial function and dysfunction in RPE cells in hand, combined with a detailed mechanistic understanding of how these microRNAs are transferred from cell to cell, we can use small interfering RNAs to target specific microRNAs and block their
adverse effects on mitochondria function and their transfer to
other RPE cells.
Dr. Pope's research
on the
adverse effects of anabolic - androgenic steroids (AAS) and
other performance - enhancing drugs addresses psychiatric
effects of AAS use and ASS withdrawal, the cardiac toxicity of AAS (which is emerging as a serious public health problem), and cognitive deficits in AAS users.
«The evidence for
adverse reproductive outcomes (infertility, cancers, malformations) from exposure to endocrine - disrupting chemicals is strong, and there is mounting evidence for
effects on other endocrine systems, including thyroid, neuroendocrine, obesity and metabolism, and insulin and glucose homeostasis.»
These findings jibe with two
other large - scale studies that have suggested acetaminophen may have an
adverse effect on a baby's brain during pregnancy, said Dr. Andrew Adesman.
So if you are a serious bodybuilder, you do not want to get involved in alcohol consumption as it has many
adverse effects on not just muscle gain, but
other body functions as well.
OTHER ADVERSE EFFECTS OF GOVERNMENT DIETARY GUIDELINES
ON HEALTH Decades of effort by government officials to reduce salt intake by the U.S. population have met with limited success due to the natural salt cravings that kick in when salt intake is not adequate.
The typical dosage of NAC given as an oral supplement in clinical trials is 600 mg b.i.d., although 200 mg t.i.d. has been shown to provide benefit in just 8 weeks.27
On the
other hand, doses as high as 1 gram t.i.d. have been used in cystic fibrosis patients for 4 - 12 weeks with no
adverse effects, and in AIDs patients, oral NAC doses up to 8 grams / day did not cause clinically significant
adverse reactions.42 43 44 45 46 47
OTHER RECENT ARTICLES
ON ADVERSE EFFECTS OF LOW SALT INTAKE A 2006 study showed that sodium restriction increases the risk of heart failure, death and hospitalization.
On the
other hand, healthy aging and longevity may be related to reduced levels of inflammation and / or strong protective mechanisms that guard against its
adverse effects.
I really don't believe that this monster was created
on purpose to hurt people, but the astounding collection of
adverse effects, all packed into one food, pushed
on us by the U.S. government and
other «official» health agencies, explains why this one thing has exerted more harm than any foreign terrorist group can inflict
on us.
This is the first study to show
adverse effects of low to moderate consumption of fructose - glucose -, and sucrose - containing beverages over a period of only 3 wk
on LDL size and
other parameters of lipid and glucose metabolism as well as
on inflammatory response in healthy young men.
There are also
other foods that may be used as alternatives or supplements to medications (which often have
adverse effects on skin health).