A study
of Asian vegetarians with incomplete amino acid intake showed reduced clearing
of xenobiotics.47 Low levels
of hydrochloric acid have an
adverse impact on the availability
of dietary amino acids, even in a higher protein
diet, so stimulating the pancreas using lacto - fermented foods is crucial.
Most traditional
diets which rely on high glycemic index starches, like white rice or corn tortillas, use them in a way which minimizes their
impact on blood glucose: they are always eaten together with plenty
of vegetables, herbs and spices which provide fiber, acidity and phytonutrients slowing down the digestion
of the starches and counteracting the
adverse effects
of high blood glucose.
Rather, in the face
of a
diet such as the TWT
diet, which carries a very small glycemic load, the body's production
of glycogen through protein metabolism has a negligible
impact on blood sugar (and essentially no
adverse impact in insulin response).
The therapeutic dotential
of dietary precursor modulation by a fish - oil - supplemented
diet (n - 3 fatty acids), such as eicosapentaenoic acid (C20: 5,n - 3) and docosahexaenoic acid (C22: 6,n - 3) in the therapy
of ulcerative colitis has been shown to result in a 35 % to 50 % decrease in neutrophil production
of LTB4.28 Significant improvement in symptoms and histologic appearance
of the rectal mucosa has been observed in several small series
of patients with Crohn's disease and ulcerative colitis given fish oil at 3 to 4 g daily for 2 to 6 months in uncontrolled studies.29 However, a larger, randomized, double - blind trial comprising 96 patients with ulcerative colitis failed to reveal any benefit in remission maintenance or treatment
of relapse on 4.5 g
of eicosapentaenoic acid daily, despite a significant reduction in LTB4 synthesis by blood peripheral polymorphonuclear cells.30 It should be emphasized, however, that the anti-inflammatory actions
of the fish oils, in addition to inhibition
of LTB4, include suppression
of IL - 1 and platelet activating factor synthesis and scavenging
of free oxygen radicals.30 The
impact of increased lipid peroxidation after fish oil supplementation should be considered when altering the n - 6: n - 3 fatty acid ratio.31 Antioxidant supplementation may be able to counteract the potentially
adverse effects
of n - 3 fatty acids.