A novel strategy to screen pregnant women for malaria with rapid diagnostic tests and treat the test - positive women with effective antimalarials does not lower the risk
of adverse pregnancy outcomes compared with treating all pregnant women with the malaria preventive sulfadoxine - pyrimethamine (SP) in sub-Saharan Africa, according to an open label randomized trial published this week in PLOS Medicine by Feiko ter Kuile, of the Liverpool School of Tropical Medicine, and colleagues.
Trial 2 showed that MQ recipients had less parasitemia than placebo recipients, no difference
in adverse pregnancy outcomes or in low birth weight between the two groups, and poorer tolerability in the MQ group than the placebo group.
Women with a severe form of morning sickness who take antihistamines to help them sleep through their debilitating nausea are significantly more likely to
experience adverse pregnancy outcomes, including low birth weight babies and premature births, a UCLA study has found.
In brief, the HAPO study was a 15 - center multicultural study designed to examine the association between maternal hyperglycemia and
adverse pregnancy outcomes among women with singleton pregnancies whose OGTT results were below the thresholds that have traditionally defined gestational diabetes.
There's no evidence of an effect by Chernobyl on fertility, birth malformations, or infant mortality; nor for causing an increase
in adverse pregnancy outcomes or still births; nor for any genetic effects.
Called
the Adverse Pregnancy Outcomes Reporting System, it dispatches nurses to the babies» homes to monitor their growth and development, for up to two years if necessary.
Kangatharan C, Labram S, Bhattacharya S. Interpregnancy interval following miscarriage and
adverse pregnancy outcomes: systematic review and meta - analysis.
This was a systematic review of cohort and case - control studies that compared rates of
any adverse pregnancy outcome (such as miscarriages, preterm delivery, intrauterine growth restriction, major congenital malformations and long - term developmental outcomes) between women who experienced NVP and women who did not.
CONCLUSIONS: Our study provides biological evidence linking maternal MTHFR and dietary folate deficiencies to
adverse pregnancy outcomes in mice.
The findings, the first to link antihistamine use to
adverse pregnancy outcomes, are important because babies born before 37 weeks often are hospitalized longer than full term babies, can experience problems breathing and feeding, are more prone to infection and can suffer from developmental problems.
Research has indicated that women with periodontal disease may be at risk of
adverse pregnancy outcomes, such giving birth to a pre-term or low - birth weight baby, reports the AAP and EFP.
Interferon signaling, and a fetus's ability to detect and respond to infection, could be tied to
adverse pregnancy outcomes in humans, the researchers speculated.
«We believe such changes in the pelvic and uterine environment could influence implantation and development of placenta, predisposing them to
adverse pregnancy outcomes,» she said.
In women with a previous diagnosis of endometriosis the risks of
adverse pregnancy outcomes, including ante - and postpartum haemorrhage and preterm birth, was also significantly increased.
This database will serve as a basis for a future larger study to identify susceptible subpopulations at higher risk of
adverse pregnancy outcomes.
Because caffeine appears to increase the risk of
adverse pregnancy outcomes, including miscarriages, preterm delivery, stillbirth, and childhood leukemia (and possibly birth defects) and inhibits fetal growth, women who are pregnant or may become pregnant should avoid caffeine.
Environmental exposures and
adverse pregnancy outcomes: a review of the science.
The Hyperglycemia and
Adverse Pregnancy Outcome (HAPO) study identified a strong association between maternal glycemia and anthropometry - derived adiposity in newborn infants (7).