Not exact matches
These risks and uncertainties include, among others: the unfavorable outcome
of litigation, including so - called «Paragraph IV» litigation and other patent litigation, related to any
of our products or products using our proprietary technologies, which may lead to competition from generic
drug manufacturers; data from clinical trials may be interpreted by the FDA in different ways than we interpret it; the FDA may not agree with our regulatory approval strategies or components
of our filings for our products, including our clinical trial designs, conduct and methodologies and, for ALKS 5461, evidence
of efficacy and adequacy
of bridging to buprenorphine; clinical development activities may not be completed on time or at all; the results
of our clinical development activities may not be positive, or predictive
of real - world results or
of results in subsequent clinical trials; regulatory submissions may not occur or be submitted in a timely manner; the company and its licensees may not be able to continue to successfully commercialize their products; there may be a reduction in payment rate or reimbursement for the company's products or an increase in the company's financial obligations to governmental payers; the FDA or regulatory authorities outside the U.S. may make
adverse decisions regarding the company's products; the company's products may prove difficult to manufacture, be precluded from commercialization by the proprietary rights
of third parties, or have unintended
side effects,
adverse reactions or incidents
of misuse; and those risks and uncertainties described under the heading «Risk Factors» in the company's most recent Annual Report on Form 10 - K and in subsequent filings made by the company with the U.S. Securities and Exchange Commission («SEC»), which are available on the SEC's website at www.sec.gov.
When inflammation strikes, we are conditioned into reaching for a quick fix in the way
of pharmaceutical or prescribed
drugs such as aspirin and ibuprofen, temporary panacea's that come with their own
adverse side effects and with long term use have the potential to create a host
of health problems independently.
Two case reports and two small case series subsequently have provided reassuring evidence regarding the limited amount
of drug transferred to the infant through breast milk and the lack
of adverse side effects noted in infants by nursing mothers.5 — 8
«Since epalrestat is already on the market and has no major
adverse side effects, our study provides a proof
of principle that it could become a valuable targeted
drug for the clinical treatment
of basal - like breast cancer,» Dong says.
Seventy per cent
of the websites provided information on the safe usage
of prescription medications, including potential
side effects or
adverse reactions when combined with other
drugs.
In a final year project, MChem undergraduate student Edward Howe, working in Professor David Smith's research team in the Department
of Chemistry at York looked for a way
of eliminating the
adverse side -
effects associated pain - killing
drugs, particularly in the stomach, and the problems, such as ulceration, this could cause patients.
New findings by UH biomedical engineer Chandra Mohan and his team raise hope for a new class
of drugs to treat lupus that may not include the long list
of adverse risks and
side effects often associated with current treatments.
New findings by a biomedical engineer and his team at the University
of Houston (UH) raise hope for a new class
of drugs to treat lupus that may not include the long list
of adverse risks and
side effects often associated with current treatments for this disease.
Ishmael said even if coibamide A itself can not enter the brain or turns out to have
adverse side effects, knowing its structure and mechanism
of action can help researchers develop new
drugs that mimic coibamide A's
effects.
Although doctors have long incorporated personal information like family history into treatment plans, personalized medicine holds the promise
of revolutionizing medical care by using knowledge
of molecular biology and genetics that will allow more precise diagnoses, better diagnostic tests, greater predictability
of disease course, more successful therapies by targeting the right treatments to the right patients, and improved patient safety by selecting
drugs and their proper dosage to reduce
adverse side effects.
One
of the major parameters was the safety
of these agents in the respiratory airways and lung parenchyma, since several
of these agents are known to cause
adverse effects.23 The main
adverse effects observed were cough, transient fever and transient decrease in the respiratory functions after the aerosol administration.8, 19, 20 Moreover; it has been observed that excessive deposition
of these agents in one site
of the respiratory system can induce non-specific
side effects in the form
of pulmonary edema as observed with many other
drugs.16 These
side effects were milder when a premedication with bronchodilators and inhaled corticosteroids were administered.8, 19, 20 Until now no long term trial (> 9 months) has been performed since all patients included in previous studies had stage IV non-small cell lung cancer (NSCLC).
The objectives
of the guidelines for the rational and responsible use
of antimicrobials are: - Optimal outcome for male and female patients - Optimal use
of antibiotics (range, mode
of administration, dose, duration)- Minimizing
side effects, such as
adverse effects, development
of resistance, nosocomial infections, C. difficile infections and costs The basics
of the guidelines are evidence, international and national guidelines, the epidemiology
of antimicrobial resistance at the USZ and the ex-factory prices
of drugs.
Label the FDA approved label is the official description
of a
drug product which includes indication (what the
drug is used for); who should take it;
adverse events (
side effects); instructions for uses in pregnancy, children, and other populations; and safety information for the patient.
Adverse side effects of the Statin
Drugs include muscle damage, nerve damage, and transient global amnesia.
Sinatra says that statin
drugs can drive down LDL, yet low LDL below 80 is associated with
adverse side effects of increased risk
of cancer, aggression, cerebral bleeding, amnesia, and immune dysfunction.
How many demented nursing home patients will suffer from the
adverse side effects of statin
drugs?
Even though grapefruits alone don't do much, the researchers suggest that people might be more likely to stick with them than cholesterol - lowering
drugs, noting that most people with heart disease stop taking their statin
drugs within a couple years, because
of the
adverse side effects, whereas grapefruit alone don't have any
side effects.
Alternatively, we have plenty
of evidence that statin
drugs cause harmful
adverse side effects, especially considering a child starting a statin
drug is committed to 40 years
of drug treatment.
Exposure to loud noise such as blasts and urban noise,
adverse side effects from some
drugs, stress, deficiency
of certain minerals, etc have also been known to cause tinnitus.
Alternatives to conventional
drug based therapy treatments are becoming increasingly popular due to the inability to find a cure for SLE, along with a growing desire for a treatment plan which carries a lower risk
of adverse side effects.
The spice saffron may not only work as well as SSRI antidepressant
drugs like Prozac, Paxil, and Zoloft without the
side effects; they may be able to even treat the
adverse sexual
side effects that occur in up to 70 %
of people taking them.
Most importantly, it's an all natural approach to healing without the
adverse side effects and complications
of drugs or surgery.
Because we administer lower doses
of each individual
drug, your pet will experience fewer
adverse side effects, more complete pain relief and faster post-operative recovery.
Adverse drug events are undesired
side effects associated with a
drug or a lack
of effect (the
drug doesn't do what it's supposed to do).
Potential
adverse side effects: Bone - marrow suppression leading to reduced numbers
of white blood cells and a risk
of infection, nausea, vomiting, or diarrhea; severe chemical burns if chemotherapy
drugs leak from the vein into surrounding tissues.
A disadvantage in any sulfa
drug is a number
of adverse side -
effects, but I have not had any problems, probably because I do not keep dogs on the medication longer than recommended, and have genetically strong breeding stock.
* Approximately 70 %
of possible
adverse drug events have been in older dogs (many
of these older pets have preexisting disease, underlying milk dehydration, or are taking multiple medications that predispose to renal or gastrointestinal
side effects.)
«In common terms, an
adverse drug experience (ADE) is either an undesired
side effect, or the lack
of a desired
effect.
Because we administer lower doses
of each individual
drug, your pet will experience fewer
adverse side effects, more complete pain relief, and have a faster recovery.
When we administer lower doses
of each individual
drug, your pet will experience fewer
adverse side effects, more complete pain relief and faster post-operative recovery.
Medications can cause
drug interactions or other
adverse reactions when prescribed inappropriately; drugmakers downplay the
side effects of a medication or fail to adequately test a product before it goes to market.