Because the mutation takes
longer to
affect female mice, researchers have an opportunity to study how it changes behavior and
brain function over the entire lifespan.
Long - term goal of the project will be to visualize and manipulate tau expression also in a systemic context (organotypic slice preparations, mouse
brain) by
affecting the
function of tau mRNA - containing neuronal granules as a potential drug target for the treatment of neurodegenerative diseases.
Health improvement (allowing to post - pone / escape the diseases and thus live, healthier / disease - free
longer, but not above human MLSP of around 122 years; thus these therapies do not
affect epigenetic aging whatsoever, they are degenerative aging problems not regular healthy aging problem (except OncoSENS - only when you Already Have Cancer - which cancer increases epigenetic aging, but cancer removal thus does not change anything / makes no difference about what happens in the other cells / about what happens in the normal epigenetic «aging» course in Normal non-cancerous healthy cells) Although there is not such thing as «healthy aging» all aging in «unhealthy» (as seen from elders who are «healthy enough» who show much damage), it's just «tolerable / liveable» enough (in terms of damage accumulating) that it does not
affect their quality of life (enough yet), that is «healthy aging»: ApoptoSENS - Clearing Senescent Cells (this will have great impact to reduce diseases, the largest one, since it's all inflammation fueled by the inflammation secretory phenotype (SASP) of these senescent cells) AmyloSENS - Dissolving the Plaques (this will allow humans to evade Alzheimer's, Parkinsons and general
brain degenerescence, allowing quite a boost; making people much more easily reach the big 100 - since the
brain is causal to how
long we live; keeping
brain amyloid - free and keeping our memories / neuron sharp / means
longer LongTerm Potentiation - means
longer brain function means
longer heavy
brain mass (gray matter / white matter retention seen in «sharp - witted» Centenarians who show are younger
brain for their age), and both are correlated to MLSP).
Also called cerebral hypoxia, HAI can
affect brain function in as little as a few minutes — and the
longer the
brain loses oxygen, the more widespread the damage will be.