The pharmaceutical business model has typically focused on health conditions that
affect large populations at the expense of disease states that affect fewer people.
This is particularly prevalent in the upstream, top - down policy approach that can
affect large populations through the preventative mechanism that could affect a wider population.
Unlike the Chernobyl disaster, which mainly affected small, self - subsisting farming villages in the Ukraine, the Fukushima accident could
affect a larger population because Japan is one of the world's leading exporters of goods.
Often called the Third Pole due to how much ice and snow accumulates there, the Himalayas and Tibetan Plateau are the source of major rivers in nearby countries and changes to them can
affect the largest populations in China and India.
Researchers finally discovered what causes deadly skin condition called lethal acrodermatitis (LAD)
affecting a large population of Bull Terrier dogs.
Not exact matches
That is, it is a benefit that doesn't
affect a huge share of the immigrant
population at
large.
«Things that
affect large portions of the [employee]
population really
affect small - and medium - sized businesses more than
large businesses,» says Al Berman, executive director of DRII, The Institute for Continuity Management, a New York City - based organization that certifies businesses in contingency planning.
There is no globalisation of political regulation, state or democratic institutions which provide guarantees and exert control over decisions
affecting the various regions and
populations of the world, in the general interest of the world at
large.
A recent study from researchers at Oxford University published in the medical journal The Lancet looked at how changing weather patterns will
affect the planet's ability to grow enough food to adequately feed the global
population, and the results are terrifying: They predicted that because of
large scale agricultural changes, 247,970 could die in China alone by the year 2050.
The weed species and biomass were similar in the two systems; however, with timely removal they did not form
large populations or
affect the growth of the strawberries.
Given the structural damage caused by the earthquake to water supply systems, there is an additional risk of water borne diseases
affecting large numbers of the urban, rural and displaced
populations.
Meanwhile, rampant political corruption has haunted the country since the fall of communism, and failing public services and generalized poverty
affects a
large part of the
population.
He stressed that his union holds the
largest teacher
population in basic and second cycle schools, «therefore if you want to take any decision that
affects education in Ghana, you can not sidestep us.»
Increased traffic will
affect the rural area, including a
large population of Mennonite people.
Research Fellow, Mette Andersen, who led the study, said, «This is the
largest population - based study to examine whether levothyroxine treatment for patients with subclinical hypothyroidism can
affect their mortality.
Since the
largest portion of individuals
affected by wildfires base their final decision on physical cues, the researchers recommend that communication to this
population should focus on how to appropriately assess physical wildfire cues and the challenges of making an accurate assessment.
Despite countless findings to the contrary, a
large portion of the
population doesn't believe that scientists agree on the existence of human - caused climate change, which
affects their willingness to seek a solution to the problem, according to a 2011 study in Nature Climate Change.
Prompt action is needed most in Asia and Africa where, today,
large parts of the coastal
population are already
affected by storm surge flooding.
A variety of studies, many using long - term medical records from
large populations, have found that certain experiences
affect future descendants» health risks.
Joint hypermobility, which
affects approximately 20 percent of the
population, confers an unusually
large range of motion.
Countries with
large volumes of travellers arriving from Zika virus -
affected areas of the Americas and
large populations at risk include India (67422 travellers arriving per year; 1.2 billion residents in potential Zika transmission areas), China (238415 travellers; 242 million residents), Indonesia (13865 travellers; 197 million residents), the Philippines (35635 travellers; 70 million residents), and Thailand (29241 travellers; 59 million residents).
Many countries across Africa and Asia - Pacific may be vulnerable to Zika virus outbreaks, with India, China, the Philippines, Indonesia, Nigeria, Vietnam, Pakistan, and Bangladesh expected to be at greatest risk of Zika virus transmission due to a combination of high travel volumes from Zika
affected areas in the Americas, local presence of mosquitos capable of transmitting Zika virus, suitable climatic conditions,
large populations and / or limited health resources, according to a new modelling study published in The Lancet Infectious Diseases.
The body colour of Robichon's lab aphids is
affected by environmental conditions, with the cold favouring green aphids, optimal conditions resulting in orange ones and white ones appearing when the
population is
large and faced with limited resources.
«These findings dispute the commonly held notion that the gap in donor supply in certain geographic areas is due to
large populations of racial and ethnic minorities who are less likely to consent for donation, thus
affecting the geography of available organs,» said the study's lead author, David Goldberg, MD, MSCE, an assistant professor in the division of Gastroenterology at Penn..
The International Osteoporosis Foundation (IOF) estimates that by 2050 more than 50 % of all osteoporotic fractures will occur in Asia — and China will be the country which is most
affected due to its
large population of seniors.
«From the scientific perspective, this study suggests that ecosystem and species - level migration processes
affecting population dynamics in marine environments such as the Gulf of Mexico may be operating at a
larger scale than typically appreciated or examined,» Jue said.
The researchers support restoration of
large - reef predators as a way to achieve better balance and biodiversity, but they are not optimistic that this would
affect the burgeoning lionfish
population.
«This can
affect conservation plans because if snow leopards are eating more
large ungulates, we need to make sure we're maintaining those
large ungulate
populations.
But this is the first
large population study to look at how a new diagnosis of depression might
affect people with coronary heart disease, according to researchers.
In a paper published in Nature in September 2013, we describe results of the
largest study to date integrating RNA and genome sequencing data from multiple human
populations, and provide a comprehensive map of how genetic variation
affects the transcriptome.
Thus, introgression seems not only to
affect a
large portion of the genome but frequently occurs through the entire range of parental
populations.
By analyzing genome sequence data from human
populations, including 1269 individuals from sub-Saharan Africa, we identify a diverse array of
large copy number variants
affecting the host invasion receptor genes GYPA and GYPB We find that a nearby association with severe malaria is explained by a complex structural rearrangement involving the loss of GYPB and gain of two GYPB - A hybrid genes, which encode a serologically distinct blood group antigen known as Dantu.
Food allergies are known to
affect quite a
large number of our
population, with estimates that about three percent of adults and up to eight percent of our children are
affected.
Conversely, within non-diabetic
populations, periods of IER (75 - 85 % ER on restricted days) do not typically
affect fasting glucose levels 37, 41, 45, 48 or HbA1c 41, 48; results of which can often be replicated by short term CER studies.62 - 65These findings are unsurprising given that frank hyperglycaemia within the T2DM diagnostic range is effectively a late - stage manifestation of IR, which along with compensatory increases insulin secretion, can precede the onset of T2DM by many years.66, 67 Findings from one
large scale prospective cohort study, Whitehall II, reveal a sharp increase in the trajectory towards fasting hyperglycaemia which is only detectable three years prior to diagnosis with T2DM.67 Consequently, it can be argued that changes in circulating insulin concentrations, fasting (hepatic) insulin sensitivity and glucose uptake / clearance are more sensitive markers of deteriorating glucose control than fasting glycaemia in non - diabetics.68 - 70
The researchers found that «1) ingestion of a
large number of calories at one time (binge eating) impacts metabolic parameters even when total calories and macronutrients are appropriate for weight; 2) the timing of energy intake is an independent determinant of the diurnal rhythm of leptin secretion, indicating a relatively acute
affect of energy balance on leptin dynamics; 3) the mechanism of exaggerated insulin secretion after a binge meal remains to be determined, but may be related to the altered diurnal pattern of leptin secretion; and 4) as most binge eating episodes in the
population are associated with the ingestion of excess calories, it is hypothesized that binge eating behavior is associated with even greater metabolic dysfunction than that described herein.»
And, like many other public health issues,
affected populations tend to be concentrated in low - income areas home to
large numbers of minorities.
Affected populations tend to be concentrated in low - income areas home to
large numbers of minorities.
The concern expressed by states with
large undocumented immigrant
populations is that asking about citizenship will scare people off, forms won't get filled out and the count won't be accurate,
affecting federal funding and the number of congressional seats.
Schools with
large minority
populations would be
affected disproportionately if future tests lead to similar performance gaps.
As with the national data, we should be mindful that demographic changes can
affect achievement trends, especially as Hispanic students make up an ever -
larger proportion of our
population.
Moreover, these economic struggles have not
affected all
populations equally, contributing to
large gaps among black, white, and Hispanic youth.
Although a
large number of consumers and buyers had opted for offers with locked mortgage rates, according to the Canadian Association of Accredited Mortgage Professionals, there is still a
large population, constituting almost 31 percent of all mortgages, who will be directly
affected by any sudden hike in the interest rate.
In the same way that inbreeding among human
populations can increase the frequency of normally rare genes that cause diseases, the selective breeding that created the hundreds of modern dog breeds has put purebred dogs at risk for a
large number of health problems,
affecting both body and behavior.
In consequence, a
large number of carriers and
affected dogs must be present in the Old English sheepdogs»
population.
Without
large - scale restoration of degraded habitats to make them capable of supporting
larger fish and shellfish
populations there will be fewer fish in the future and without healthy growing corals there will be fewer beaches or tourism income,
affecting all business owners on the island.
ITINERANT at Queens Museum will present a selection of Performance Art works by local and international artists whose works reflect on issues
affecting diverse
populations living in Queens, and NYC at
large.
For example, urban heat islands may be
affecting a
large fraction of the world's
population (perhaps as much as 50 %, the reported fraction of the
population living in cities today)-- so is that a global effect, or a local one?
Several
large cities (
population 100,000 — 500,000) are in the
affected area.
As glaciers recede and disappear entirely,
large populations of people who rely on the melt water will be adversely
affected.
While most global regions are
affected,
populations residing in
large cities in poor countries appear to be the worst hit, data released by the World Health Organization (WHO) on Thursday revealed.