Sentences with phrase «affected by lymphoma»

The lymph nodes are the most common areas affected by lymphoma, but it can grow anywhere in the body.

In cats, lymphoma cells (like lymphocytes) can grow anywhere in the body, but there are certain sites that are more commonly affected by lymphoma than others (such as the GI tract, mediastinum, and lymph nodes).

Not exact matches

This is in accordance with previous reports that decitabine and 5 - azacytidine produce a marked synergistic effect in combination with suberoylanilide hydroxamic acid and romidepsin in T - lymphoma cell lines by modulating cell cycle arrest and apoptosis.26, 27 As a mechanism of action, KMT2D mutations of B - lymphoma cells promote malignant outgrowth by perturbing methylation of H3K4 that affect the JAK - STAT, Toll - like receptor, or B - cell receptor pathway.28, 29 Here our study indicated that dual treatment with chidamide and decitabine enhanced the interaction of KMT2D with the transcription factor PU.1, thereby inactivating the H3K4me - associated signaling pathway MAPK, which is constitutively activated in T - cell lymphoma.13, 30,31 The transcription factor PU.1 is involved in the development of all hematopoietic lineages32 and regulates lymphoid cell growth and transformation.33 Aberrant PU.1 expression promotes acute myeloid leukemia and is related to the pathogenesis of multiple myeloma via the MAPK pathway.34, 35 On the other hand, PU.1 is also shown to interact with chromatin remodeler and DNA methyltransferease to control hematopoiesis and suppress leukemia.36 Our data thus suggested that the combined action of chidamide and decitabine may interfere with the differentiation and / or viability of PTCL - NOS through a PU.1 - dependent gene expression program.

Celiac patients may be susceptible to small bowel cancers or even lymphoma, since immune cells are also affected, thanks to the inflammation caused by celiac disease.

The only way to definitively diagnose lymphoma is by biopsying affected tissues.

Lymphoma is classifed by anatomic area affected.

Many older cats are affected by intestinal neoplasia, often lymphoma or pancreatic cancer to name a couple, but given how long this has been going on, I put it lower on my differential list.

They also are affected by several types of cancer like lymphoma, stomach cancer, and skin cancer.

Diagnosing lymphoma usually starts by obtaining cells of the affected organ with a needle for a clinical pathologist to examine.

For dogs with lymphoma, a small surgical incision is made over one of the lymph nodes affected by the cancer and a small wedge - shaped piece of tissue is removed from the affected lymph node.