Conduct clinical trials in a petri dish using the actual
affected human cell types — from patients rather than from surrogate models (e.g. animals).
Not exact matches
Since pseudouridine modifications may
affect various RNA molecules in different
types of normal and malignant
cells, «our discoveries pave the way for future avenues of research aimed at exploring the role of pseudouridine in
human development disease,» concludes Cristian Bellodi.
In their latest study, they tested compounds against
cells from nine different
types of
human cancer, including common
types affecting blood, colon, breast, prostate, ovaries, kidneys, and lungs.
Scientists can now reprogram
human skin
cells to make working
cells that resemble «medium spiny neurons», the
type of brain
cell that is most
affected early in Huntington's disease.
Tseng Laboratory scientists are interested in learning more about the function of
human brown fat
cells, including whether
humans have two
types of BAT, and understanding how BMP and related factors
affect human brown fat production.
mTOR - dependent proliferation defect in
human ES - derived neural stem
cells affected by myotonic dystrophy
type 1.
Genome editing of a
human embryo would
affect every
cell in the embryo's resulting fetus, as opposed to altering the DNA of a select
type of
cells — such as the stem
cells that produce blood
cells.
The researchers then successfully prodded what they call keratinocyte - derived iPS
cells or KiPS
cells to distinguish them from fibroblast - derived iPS
cells into becoming all the
cell types in the
human body, including heart muscle
cells and dopamine - producing neurons, which are
affected by Parkinson's disease.