Dr Andy Grierson, fellow lead investigator, added: «Diseases such as ALS and FTD are commonly associated with large protein clumps that accumulate in
affected nerve cells.
For the first time, scientists found that in spinal muscular atrophy (SMA),
the affected nerve cells that control muscle movement, or motor neurons, have defects in their mitochondria, which generate energy used by the cell.
«It was crucial to establish a cellular system with similar characteristics of
the affected nerve cells in the patients,» Prigione says.
Does
this affect these nerve cells?»
ALS, or amyotrophic lateral sclerosis, is a progressive neurodegenerative disease that
affects nerve cells in the brain and the spinal cord.
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that
affects nerve cells in the brain and the spinal cord.
Likewise, high blood sugar can also
affect nerve cells in the ear and cause impaired hearing.
Eliminate the artificial sweetener aspartame which contains excitotoxins known to
affect nerve cells, triggering migraines.
Parkinson's disease is a neurodegenerative disorder that
affects the nerve cells in the brain responsible for producing dopamine.
Carole Brody Fleet learned firsthand how financially devastating a spouse's death can be when her husband died of amyotrophic lateral sclerosis (ALS), a disease often referred to as Lou Gehrig's disease,
that affects nerve cells in the brain and spinal cord.
According to the ALS Association, ALS or amyotrophic lateral sclerosis, is a progressive neurodegenerative disease that
affects nerve cells in the brain and spinal cord.
Not exact matches
This damages some of the
nerve cells in the brain, and
affects my dad's memory, decision - making and personality.
A growing body of research indicates that the B2M - MHC I complex, which is present in all
cells in the body except red blood
cells and plasma
cells, can act in the brain in ways not obviously related to immunity — guiding brain development, shaping
nerve cell communication, and even
affecting behavior.
It establishes a lifelong infection that leads to sores in
affected tissues when active and hides in
nerve cells during its latent phase.
But the enzyme has other jobs in the brain, such as potentially
affecting the ability of
nerve cells to communicate properly.
Nerve cells have a particularly high energy demands, therefore defects in the
cell's energy generators will crucially
affect their survival.
The research is also the first to demonstrate beneficial effects of UDCA on dopaminergic neurons, the
nerve cells affected in Parkinson's disease, in a fly model of Parkinson's disease which carries the same genetic change as some patients with the condition.
Blood from people
affected by the 2014 Zika outbreak in French Polynesia provides the first evidence that the virus can make the immune system attack
nerve cells
These conditions are distinguished by the different types of brain
nerve cells that are first
affected and by the symptoms that first appear.
«In that case, we will also have to ask how such changes
affected the functions and connectivity of the
nerve cells involved.»
Scientists are studying how oscillations generated by
nerve cells affect brain function.
When the optic
nerve is injured, there are tears and swelling in the
affected area that causes the
nerve cells to die.
The disease is known to
affect motor neurons —
nerve cells that control muscles — in the brain, brainstem and spinal cord.
But this came from work in my laboratory and others that suggested that
nerve cells in
affected regions of the Alzheimer brain looked like they were trying to divide.
It is clear, however, that volatile anesthetics, which are more soluble in lipids than in water, primarily
affect the function of ion channel and neurotransmitter receptor proteins in the membranes of
nerve cells, which are lipid environments.
Researchers from universities in the UK and Australia found that that neurotransmitter (a chemical compound that sends impulses between
nerve cells and
affects everything from sleep to aggression in humans) spurs a cascade of Dr. Jekyll - to - Mr.
Huntington's disease is a genetic disorder that
affects around 1 in every 10,000 people and damages
nerve cells in the brain.
A major challenge has been to find a way to better understand the way the disease
affects human
nerve cells.
MG
affects the transmission of signals between the peripheral motoric
nerve cells and muscles, resulting in muscular fatigue in the patient,» Dr Harbo explains.
«A number of tests demonstrated that these artificially created
cells had all of the properties of the
affected nerves, including the calcium imbalance and reduced energy production observed in patients.
«This study suggests that amyloid deposition in the gray matter
affects the associated white matter connections, which are essential for conducting messages across the billions of
nerve cells in the brain, allowing for all aspects of mental function.»
As a result, they are too broad: They
affect more than one type of receptor, on more than one kind of
nerve cell, in more than one part of the brain.
In other neurodegenerative diseases, such as Parkinson's — which primarily
affects a person's motor abilities — scientists know that
nerve cells begin to die long before symptoms appear.
The social environment seems to
affect the receptors on
nerve cells that respond to neurotransmitters like serotonin, which in turn changes how alcohol
affects nerves.
To see how courting is
affected when neurons are hyperactivated, they used flies with a version of a gene that was stuck in the «on» state in clumps of
nerve cells.
It may, for example, partly account for the differences in brain structure and behavior between identical twins, and could even
affect thought processes by subtly influencing the changes in
nerve cell connections that occur with experience.
Neurotrophic factors
affect the survival and growth of
nerve cells.
The mutation, which has been found in people with ADHD, autism and bipolar disorder,
affects the function of DAT, a protein that regulates the brain's supply of the neurotransmitter by removing excess dopamine from the synapse, or the space between
nerve cells.
A fraction of the FTD patients show symptoms consistent with ALS, a disease in which the
nerve cells that control the muscles, in the brain and spinal cord, are
affected.
«Since cholesterol is required by neurons to form synapses (connections) with other
cells, this decrease in cholesterol could
affect how
nerves function for appetite regulation, behavior, memory and even pain and motor activity,» says Dr. Kahn, who is also Mary K. Iacocca Professor of Medicine at Harvard Medical School.
There is a significant decrease in the level of calcium when
nerve cells are
affected by Parkinson's disease.
Specifically, Gibson's team wanted to know how jet lag would
affect the production of neurons, or
nerve cells.
Macrophage depletion alters the blood —
nerve barrier without
affecting Schwann
cell function after neural injury.
We found that an unusually high number of genes
affected by these DNA deletions / duplications are associated with the functioning of synaptic transmission between
nerve cells.
«Even if the
nerve cells have been
affected over a long term, gastric bypass still improves toward normal function.»
This visualization shows tightly - packed DNA in a mouse
cell's nucleus at different stages of development, seen here in a semi-triangular form as a mature
nerve cell; in a roundish shape as a multipotent stem
cell; in a more oval form as a neuronal progenitor; and as a more fragmented structure that shows how removing a specialized binding protein (HP1β knockout)
affects the structure of the DNA - packing material, called heterochromatin, in a mature neuron.
Despite behavioral and neurological concerns, brain areas normally
affected by HD, the striatum and cortex, did not contain damaged
nerve cells.
A medical procedure, ECT uses brief, low - energy electrical pulses to stimulate
nerve -
cell activity in the area of the brain that
affects mood.
A U-M alumna who sought to avoid passing a deadly disease to her son has given scientists a gift that could help many more families
affected by the same disease: an embryo that has allowed U-M researchers to produce stem
cells and
nerve cells that contain the crucial disease - causing genetic defect.
Stress can
affect hormone levels in the body and reduces the density of
nerve cells in the brain, the study authors said at the time.