Sentences with phrase «affecting human protein»

Darwinian and demographic forces affecting human protein coding genes Nielsen, R., M. J. Hubisz, I. Hellmann, D. Torgerson et al. 2009.

Darwinian and demographic forces affecting human protein coding genes.

Not exact matches

Resistant starch is gaining momentum in the nutrition community due to emerging evidence in animal studies and some limited evidence in human studies suggesting that RS may positively affect body composition, favorably impact blood lipid and blood glucose levels and increase the amount of good bacteria in the colon, and may enhance satiety when consumed with whey protein.

Before this can happen though, Teixeira said that his team will first have to determine whether the Stk11 gene or the other genes and proteins it controls are similarly affected in the human form of BPH.

The vaccine consists of human viral proteins inserted into a similar virus affecting rhesus monkeys.

The newly identified gene affects accumulation of amyloid - beta, a protein believed to be one of the main causes of the damage that underpins this brain disease in humans.

To see whether cancer stem cell renewal involves a chain of events similar to that used by embryonic stem cells, and whether the process was affected by oxygen levels, Semenza and graduate student Chuanzhao Zhang focused their studies on two human breast cancer cell lines that responded to low oxygen by ramping up production of the protein ALKBH5, which removes methyl groups from mRNAs.

Therefore, the research shows that these mutations affecting the signalling route which depends on the ATM protein, as well as the drugs inhibiting the function of this signalling route such as some anti-tumour drugs, could produce infertility problems in humans.

The new Mount Sinai study reveals how loss of a protein called Sirtuin1 (SIRT1) affects the ability of blood stem cells to regenerate normally, at least in mouse models of human disease.

So far, scientists have found that different populations of living humans have inherited the Neandertal version of genes that cause diabetes, lupus, and Crohn's disease; alter immune function; and affect the function of the protein keratin in skin, nails, and hair.

A region of the gene that produces the PACAP38 protein has held nearly constant, even in humans, presumably because the protein plays diverse roles in neuron communication and is essential for normal development of the cerebellum, affecting brain cell migration, for example.

«In addition, many of the proteins involved in secretion are unlike any human proteins, which means we may be able to disable them without adversely affecting important human proteins.»

Her work showed that these proteins are increasingly found to affect diseases of high impact in human health, including autoimmune disorders, cancer and metabolic diseases.

Unlike previously described mutations causing dilated cardiomyopathy that affect structural proteins, this mutation deletes 4,846 bp of the human transcriptional coactivator gene EYA4.

Telomere length predicts both cellular health and disease in rodent models and humans.8 Shorter telomeres predict onset of cardiometabolic diseases of aging.9 Chronic stress is associated with higher inflammation, shorter telomeres, and lower activity levels of telomerase, the cellular enzyme that elongates telomeric DNA.10, 11 Levels of amyloid beta (Aβ) proteins circulating in the blood appear to be stress - related in rodent models12 and may be affected by stress reduction, and greater Aβ42 / Aβ40 ratios are associated with lower risk of dementia.13

By examining the results of genome - wide association studies (GWAS) in conjunction with experiments on mouse and human red blood cells (RBCs), researchers in the lab of Whitehead Institute Founding Member Harvey Lodish have identified the protein cyclin D3 as regulating the number of cell divisions RBC progenitors undergo, which ultimately affects the resulting size and quantity of RBCs.

Research published in the Journal of Biological Chemistry shows that a rare type of glycosylation affects the function of an important protein for human development and cancer progression.

Increased permissivity of monkey cells to human adenovirus multiplication is affected by culturing conditions and correlates with both synthesis of virion fiber protein and altered splicing of its mRNA

Human mutations affecting this subgroup of ADAMTS / ADAMTSL proteins phenocopy all or several aspects of genetic disorders caused by mutations in the fibrillin - 1 gene itself, suggesting a functional relationship.

Complexes of DNA with lipids and proteins provide an alternative to viruses, and researchers are also experimenting with introducing a 47th (artificial human) chromosome to the body that would exist autonomously along side the standard 46 chromosomes, presumably not affecting their functioning or causing any mutations.

Veldhorst MAB, Westerterp KR, van Vught AJAH, Westerterp - Plantenga MS. Presence or absence of carbohydrates and the proportion of fat in a high - protein diet affect appetite suppression but not energy expenditure in normal - weight human subjects fed in energy balance.

Blomstrand, E. and Saltin, B. BCAA intake affects protein metabolism in muscle after but not during exercise in humans.

Fact is, toxicological studies of the effects of algae (primarily spirulina) consumption on humans and animals, including feeding as much as 800mg / kg, and replacing up to 60 % of protein intake with algae sources, have shown no toxic effects, and in contrast, algae intake has actually been found to prevent damage caused by toxins that affect the heart, liver, kidneys, neurons, eyes, ovaries, DNA, and testicles.

Other studies have shown that dogs affected by this syndrome show deposition of amyloid (a protein) in their brains in patterns very similar to the amyloid plaques found in the brains of human Alzheimer's patients.

Other studies have shown that dogs affected by this syndrome show deposition of a protein called amyloid in their brains in patterns similar to the amyloid plaques found in the brains of humans with Alzheimer's disease.