Sentences with phrase «affecting synaptic function»

The lipid type, ceramide, also has a functional role in various signaling pathways and affects synaptic function, although its primary role is not in the synapse, but providing structure in cell membranes.

Not exact matches

Maternal alcohol consumption prior to and during pregnancy significantly affects cognitive functions in offspring, which may be related to changes in cyclin - dependent kinase 5 because it is associated with modulation of synaptic plasticity and impaired learning and memory.

We found that an unusually high number of genes affected by these DNA deletions / duplications are associated with the functioning of synaptic transmission between nerve cells.

Astrocytes can regulate neuronal synapses by secreting factors that affect both synapse formation and synaptic function.

''... we hypothesize that repeated stress - related allostatic overload may affect brain function at three basic levels: (a) at the cellular level, it may compromise proteostasis (e.g. tau protein), organelles homeostasis, and induce epigenetic changes in neuronal DNA; (b) at the tissue level it may affect intracellular communication (synaptic contacts), number of cells (reduction of neuronal density), composition of the extracellular matrix (accumulation of amyloid plaques), and neuroinflammation; (c) at the systemic levels it may alter the brain's regulation of behavior (cognitive decline).